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  Welcome  

Welcome to the Max Planck Institute of Molecular Physiology

We are an international team of cell biologists, structural biologists and chemists engaged in a young, future-oriented research field: systems biology.

The goal of our work is not to investigate individual elements of cells or tissues, but rather to obtain an integrated picture of all processes which regulate the metabolism, growth and proliferation of living organisms.

The reason: Genes and proteins are not static building blocks of life. Rather, they are more like capricious divas: How they behave depends to a great extent on their surroundings and their respective contacts. And it is precisely this social behavior of the molecules which determines whether a cell stays healthy or not.

To unravel these networks, researchers from different disciplines are venturing together into the nanocosmos and are exploring at the atomic level. This includes elucidating the structure of individual molecules, live imaging of the cell interior, and even the synthesis of chemical substances, which can influence the dynamics of specific molecules.

Our focus is on basic research – with a clear objective: We are striving to understand the collective behavior of the involved molecules, because this is crucial to understanding complex diseases like cancer.

 

Prof. a.D. Roger S. Goody

Managing Director
Max Planck Institute of Molecular Physiology




    News

Latest Publications

Oesterlin, L. K., R. S. Goody and A. Itzen:
Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor.
Proceedings of the National Academy of Sciences of the USA 109, 5, 5621-5626 (2012).

Das, D., Z. Tnimov, U. T. T. Nguyen, G. Thimmaiah, H. Lo, D. Abankwa, Y. Wu, R. S. Goody, H. Waldmann and K. Alexandrov:
Flexible and General Synthesis of Functionalized Phosphoisoprenoids for the Study of Prenylation in vivo and in vitro.
ChemBioChem 13, 5, 674-683 (2012).

Dittmann, M., M. Sadek, R. Seidel and M. Engelhard:
Native chemical ligation in dimethylformamide can be performed chemoselectively without racemization
Journal of Peptide Science 18, 5, 312-316 (2012).

Potowski, M., M. Schürmann, H. Preut, A. P. Antonchick and H. Waldmann:
Programmable enantioselective one-pot synthesis of molecules with eight stereocenters
Nature Chemical Biology 8, 428-430 (2012).




Events and Seminars

Lecture on Friday, May 18th 2012 at 11.00 a.m., lecture hall

Speaker: Dr. Eric Griffis,
Wellcome Trust Centre for Gene Regulation and Expression College of Life Sciences, University of Dundee, UK

Title: "Spindly: a protein essential for chromosome alignment and SAC activity"


Lecture on Monday, May 21st 2012 at 5.00 p.m., lecture hall

Speaker: Prof. Dr. Jawdat Al-Bassam,
Assistant Professor, University of California Davis, USA

Title: "Mechanisms of Microtubule Dynamics Regulation by TOG domain proteins, XMAP215/Dis1 and CLASP;


Lecture on Wednesday, May 30th 2012 at 11.00 a.m., lecture hall

Speaker: Dr. Sabine Petry,
Howard Hughes Medical Institute, University of California, San Francisco, USA

Title: "Role and Mechanism of Microtubule Nucleation within the Mitotic Spindle"




Job Oppertunities

The latest Job Oppertunities can be foundText Link Internhere and on the homepage of the Text Link ExternMax Planck Society.

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© 2012, Max Planck Institute of Molecular Physiology, Dortmund