February 20, 2017
The MPI of Molecular Physiology is part of the DivIDE Network, a Marie Skłodowska-Curie actions training network funded by the European Commission’s H2020 Programme. Andrea Musacchio is leading a project on “Spindle checkpoint silencing by the Dynein-Dynactin complex” and supervising a second project on the “Regulation of dynein function”.
The aim of DivIDE is to investigate the principles of cell division and the underlying mechanisms, also by reproducing cell division in vitro by using synthetic approaches. DivIDE wants to support the mutual exchange among physicists, chemists, biochemists, structural biologists and cell biologists to train a new generation of molecular engineers thinking in an interdisciplinary way.
The first annual meeting with all supervisors and students of the DiviDE network took place at the MPI of Molecular Physiology from the 11th to the 13th February 2017. The students were introduced to protein biochemistry, chemical kinetics, and protein labelling in a five-day workshop. They were taking part in a journal club where they could discuss recently published papers at the MPI with the first-authors. A practical part involved the practice of methods to measure protein-protein interactions like fluorescence polarization or Isothermal Titration Calorimetry. Furthermore, the students got insights into biochemical and cellular assays, high throughput screening, rational drug design and pharmacological profiling.
The first DivIDE meeting was judged a total success by the students. Especially the intense exchange with the other scientist was of great value.