Suchergebnisse

Goebel, L.; Kirschner, T.; Koska, S.; Rai, A.; Janning, P.; Maffini, S.; Vatheuer, H.; Czodrowski, P.; Goody, R. S.; Müller, M. et al.; Rauh, D.: Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife (2023)

d'Amico, E.; Ud Din Ahmad, M.; Cmentowski, V.; Girbig, M.; Müller, F.; Wohlgemuth, S.; Brockmeyer, A.; Maffini, S.; Vetter, I. R.; Carter, A. P. et al.; Perrakis, A.; Musacchio, A.: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. The Journal of Cell Biology: JCB 221 (2022)

Raisch, T.; Ciossani, G.; d'Amico, E.; Cmentowski, V.; Carmignani, S.; Maffini, S.; Merino, F.; Wohlgemuth, S.; Vetter, I. R.; Raunser, S. et al.; Musacchio, A.: Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. The EMBO Journal, e110411, S. 1 - 22 (2022)

Kucher, S.; Elsner, C.; Safonova, M.; Maffini, S.; Bordignon, E.: In-Cell Double Electron-Electron Resonance at Nanomolar Protein Concentrations. The Journal of Physical Chemistry Letters 12 (14), S. 3679 - 3684 (2021)

Piano, V.; Alex, A.; Stege, P.; Maffini, S.; Stoppiello, G. A.; Huis in´t Veld, P. J.; Vetter, I. R.; Musacchio, A.: CDC20 assists its catalytic incorporation in the mitotic checkpoint complex. Science 371 (6524), S. 67 - 71 (2021)

Burigotto, M.; Mattivi, A.; Migliorati, D.; Magnani, G.; Valentini, C.; Roccuzzo, M.; Offterdinger, M.; Pizzato, M.; Schmidt, A.; Villunger, A. et al.; Maffini, S.; Fava, L. L.: Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26. The EMBO Journal 40 (4), e104844, S. 1 - 22 (2020)

Singh, P.; Pesenti, M.; Maffini, S.; Carmignani, S.; Hedtfeld, M.; Petrovic, A.; Srinivasamani, A.; Bange, T.; Musacchio, A.: BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis. Molecular Cell 81 (1), S. 67 - 87 (2020)

Alex, A.; Piano, V.; Polley, S.; Stuiver, M.; Voss, S.; Ciossani, G.; Overlack, K.; Voss, B.; Wohlgemuth, S.; Petrovic, A. et al.; Wu, Y.-W.; Selenko, P.; Musacchio, A.; Maffini, S.: Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology. eLife 8, e48287, S. 1 - 50 (2019)

Corno, A.; Chiroli, E.; Gross, F.; Vernieri, C.; Matafora, V.; Maffini, S.; Cosentino Lagomarsino, M.; Bachi, A.; Ciliberto, A.: Cellular response upon proliferation in the presence of an active mitotic checkpoint. Life Science Alliance 2 (3), e201900380, S. 1 - 16 (2019)

Pesenti, M.; Prumbaum, D.; Auckland, P.; Smith, C.; Faesen, A. C.; Petrovic, A.; Erent, M.; Maffini, S.; Pentakota, S.; Weir, J. R. et al.; Lin, Y.-C.; Raunser, S.; McAinsh, A. D.; Musacchio, A.: Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80. Molecular Cell 71 (6), e10, S. 923 - 939 (2018)

Ciossani, G.; Overlack, K.; Petrovic, A.; Huis in´t Veld, P. J.; Koerner, C.; Wohlgemuth, S.; Maffini, S.; Musacchio, A.: The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases. The Journal of Biological Chemistry 293 (26), S. 10084 - 10101 (2018)

Pentakota, S.; Zhou, K.; Smith, C.; Maffini, S.; Petrovic, A.; Morgan, G. P.; Weir, J. R.; Vetter, I. R.; Musacchio, A.; Luger, K.: Decoding the centromeric nucleosome through CENP-N. eLife, 6:e33442, S. e33442:1 - e33442:25 (2017)

Kösling, S. K.; Fansa, E. K.; Maffini, S.; Wittinghofer, A.: Mechanism and dynamics of INPP5E transport into and inside the ciliary compartment. Biological Chemistry 399 (3), S. 277 - 292 (2017)

Overlack, K.; Bange, T.; Weissmann, F.; Faesen, A. C.; Maffini, S.; Primorac, I.; Müller, F.; Peters, J.-M.; Musacchio, A.: BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling. Current Biology 27 (19), S. 2915 - 2927 (2017)

Mosalaganti, S.; Keller, J.; Altenfeld, A.; Winzker, M.; Rombaut, P.; Saur, M.; Petrovic, A.; Wehenkel, A.; Wohlgemuth, S.; Müller, F. et al.; Maffini, S.; Bange, T.; Herzog, F.; Waldmann, H.; Raunser, S.; Musacchio, A.: Structure of the RZZ complex and molecular basis of its interaction with Spindly. The Journal of Cell Biology: JCB 216 (4), S. 961 - 981 (2017)

Faesen, A. C.; Thanasoula, M.; Maffini, S.; Breit, C.; Müller, F.; Van Gerwen, S.; Bange, T.; Musacchio, A.: Basis of catalytic assembly of the mitotic checkpoint complex. Nature 542 (7642), S. 498 - 502 (2017)

Isokane, M.; Walter, T.; Mahen, R.; Nijmeijer, B.; Hériché, J.-K.; Miura, K.; Maffini, S.; Ivanov, M. P.; Kitajima, T. S.; Peters, J.-M. et al.; Ellenberg, J.: ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores. The Journal of Cell Biology: JCB 212 (6), S. 647 - 659 (2016)

O’Connor, A.; Maffini, S.; Rainey, M. D.; Kaczmarczyk, A.; Gaboriau, D.; Musacchio, A.; Santocanale, C.: Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biology Open 5 (1), S. 11 - 19 (2015)

Overlack, K.; Primorac, I.; Vleugel, M.; Krenn, V.; Maffini, S.; Hoffmann, I.; Kops, G. J. P. L.; Musacchio, A.: A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint. eLife, S. 05269:1 - 05269:52 (2015)

Basilico, F.; Maffini, S.; Weir, J.; Prumbaum, D.; Rojas, A. M.; Zimniak, T.; De Antoni, A.; Jeganathan, S.; Voss, B.; Van Gerwen, S. et al.; Krenn, V.; Massimiliano, L.; Valencia, A.; Vetter, I. R.; Herzog, F.; Raunser, S.; Pasqualato, S.; Musacchio, A.: The pseudo GTPase CENP-M drives human kinetochore assembly. eLife 3, S. e02978-1 - e02978-28 (2014)