Alex Bird

The function and regulation of microtubule networks 


Contact

Phone: +49 (231) 133-2156  
Fax: +49 (231) 133-2299

       www.bird-lab.org

Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP (2017). Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell 169(7):1303-1314.e18.
doi: 10.1016/j.cell.2017.05.025.

CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading (2017). Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair. eLife 14(2):e1002369
doi: 10.7554/eLife.23352.


2016

Bendre S , Hall C, Rondelet A, Wöstehoff N., Lin Y-C, Brouhard GJ, and Bird AW (2016). GTSE1 tunes microtubule dynamics for chromosome alignment and segregation through MCAK inhibition. J Cell Biol 215(5):631-647.
doi: 10.1083/jcb.201606081

2014

El-Labban A, Zisserman A, Toyoda Y, Bird AW, Hyman AA (2014). Temporal models for mitotic phase labelling. Medical Image Analysis 18, 977-988
http://dx.doi.org/10.1016/j.media.2014.05.003 .

2012

Ross K, Sedello AK, Todd GP, Paszkowski-Rogacz M, Bird AW, Ding L, Grinenko T, Behrens K, Hubner N, Mann M, Waskow C, Stocking C, Buchholz F (2012). Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells. Blood 119(18):4152-61.
doi: 10.1182/blood-2011-09-382390.

Aguirre-Portolés C, Bird AW, Hyman A, Cañamero M, Pérez de Castro I, Malumbres M (2012). Tpx2 controls spindle integrity, genome stability, and tumor development. Cancer Res 72(6):1518-28.
doi: 10.1158/0008-5472.CAN-11-1971.

Scolz M, Widlund PO, Piazza S, Bublik DR, Reber S, Peche LY, Ciani Y, Hubner N, Isokane M, Monte M, Ellenberg J, Hyman AA, Schneider C, Bird AW (2012). GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. PLoS One e51259.
doi: 10.1371/journal.pone.0051259.

2011

Dückert H, Pries V, Khedkar V, Menninger S, Bruss H, Bird AW, Maliga Z, Brockmeyer A, Janning P, Hyman A, Grimme S, Schürmann M, Preut H, Hübel K, Ziegler S, Kumar K, Waldmann H (2011). Natural product-inspired cascade synthesis yields modulators of centrosome integrity. Nat Chem Biol 8(2):179-84.
doi: 10.1038/nchembio.758.

Bird AW, Erler A, Fu J, Hériché JK, Maresca M, Zhang Y, Hyman AA, Stewart AF (2011). High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes. Nat Methods 9(1):103-9.
doi: 10.1038/nmeth.1803.


Before 2011

Hubner NC, Bird AW, Cox J, Splettstoesser B, Bandilla P, Poser I, Hyman A, Mann M (2010). Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions. J Cell Biol 189(4):739-54.
doi: 10.1083/jcb.200911091.

Bird AW, Hyman AA (2008). Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A. J Cell Biol 182(2):289-300.
doi: 10.1083/jcb.200802005.

Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA (2008). BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods 409-15. Erratum in: Nat Methods. 2008 Aug;5(8):748.
doi: 10.1038/nmeth.1199.

Bird AW, Yu DY, Pray-Grant MG, Qiu Q, Harmon KE, Megee PC, Grant PA, Smith MM, Christman MF (2002). Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. Nature 419(6905):411-5.
doi: 10.1038/nature01035.

 
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