Gerben Vader

Mechanisms of Meiosis


Phone:+49 (231) 133 - 2130
Fax:+49 (231) 133 - 2199

Vader G, Musacchio A. (2017). The greatest kinetochore show on earth. EMBO Rep 14(2):e1002369


Subramanian VV, MacQueen AJ, Vader G, Shinohara M, Sanchez A, Borde V, Shinohara A, Hochwagen A (2016). Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair. PLoS Biology 14(2):e1002369


Vincenten N, Kuhl LM, Lam I, Oke A, Kerr ARW, Hochwagen A, Fung J, Keeney S, Vader G*, Marston AL* (2015). The kinetochore prevents centromere-proximal crossover recombination during meiosis eLife 4.
doi: 10.7554/eLife.10850.

Vader G. (2015). Pch2TRIP13: controlling cell division through regulation of HORMA domains. Chromosoma
doi: 10.1007/s00412-015-0516-y


Vader G, Musacchio A (2014). HORMA Domains at the Heart of Meiotic Chromosome Dynamics. Dev Cell 31(4):389-91


Vader G, Blitzblau HG, Tame MA, Falk JE, Curtin L, Hochwagen A (2011). Protection of repetitive DNA borders from self-induced meiotic instability.  Nature 477(7362):115-9, highlighted in Nature Structural & Molecular Biology,  18, 970 (2011)                   

before 2011

Vader G, Lens SM (2010). Chromosome segregation: taking the passenger seat. Current Biology 20(20):879-8  

Liu D, Vader G, Vromans MJ, Lampson MA, Lens SM (2009). Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science 323(5919): 1350-1353
doi: 10.1126/science.1167000

Chen SY, Tsubouchi T, Rockmill B, Sandler JS, Richards DR, Vader G, Hochwagen A, Roeder GS, Fung JC (2008). Global analysis of the meiotic crossover landscape. Dev Cell 15(3): 401-415

Vader G, Lens SM (2008). The Aurora kinase family in cell division and cancer. Biochim Biophys Acta 1786(1): 60-72

Vader G, Maia AF, Lens SM (2008). The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond. Cell Div 3: 10  
doi: 10.1186/1747-1028-3-10

Vader G, Cruijsen CW, van Harn T, Vromans MJ, Medema RH, Lens SM (2007). The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions. Mol Biol Cell 18(11): 4553-4564
doi:  10.1091/mbc.E07-04-0328

Lens SM, Vader G, Medema RH (2006). The case for Survivin as mitotic regulator. Curr Opin Cell Biol 18(6): 616-622

Vader G, Medema RH, Lens SM (2006). The chromosomal passenger complex: guiding Aurora-B through mitosis. J Cell Biol 173(6): 833-837  
doi: 10.1083/jcb.200604032

Rodriguez JA, Lens SM, Span SW, Vader G, Medema RH, Kruyt FA, Giaccone G (2006). Subcellular localization and nucleocytoplasmic transport of the chromosomal passenger proteins before nuclear envelope breakdown. Oncogene 25(35): 4867-4879  

Lens SM, Rodriguez JA, Vader G, Span SW, Giaccone G, Medema RH (2006). Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres. Mol Biol Cell 17(4): 1897-1909  
doi:  10.1091/mbc.E05-08-0727

Vader G, Kauw JJ, Medema RH, Lens SM (2006). Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody. EMBO Rep 7(1): 85-92
doi: 10.1038/sj.embor.7400562

van Vugt MA, van de Weerdt BC, Vader G, Janssen H, Calafat J, Klompmaker R, Wolthuis RM, Medema RH (2004). Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis. J Biol Chem 279(35): 36841-36854
doi: 10.1074/jbc.M313681200

Go to Editor View
loading content