Researchers who seek to elucidate the complex processes of life rely on a broad spectrum of scientific methods, perspectives and ideas. We – an international team of chemists, cell biologists, biochemists and physicists – cooperate in many of our projects across research fields and thus link the expertise of our various disciplines. The aim of our research is to gain a holistic picture of how key proteins mediate vital processes and how networks of proteins regulate the behavior of living cells.
We analyze which molecular mechanisms strictly control and regulate the process of cell division to prevent faulty chromosome distribution and the resulting damage.
We investigate which signaling pathways cells use to respond to external disturbances and which errors in the collective behavior of the molecules lead to the emergence of diseases such as cancer.
We determine the spatial structure of proteins to learn how these complex molecular machines function in detail.
We develop active substances based on models from nature to target and intervene into biological processes and to investigate the interaction of molecules. We also seek to discover substances that will correct or halt the pathogenic, derailed processes.