Publikationen von Andrea Musacchio

Mapelli, M.; Musacchio, A.: MAD contortions: conformational dimerization boosts spindle checkpoint signaling. CURRENT OPINION IN STRUCTURAL BIOLOGY 17 (6), S. 716 - 725 (2007)

Musacchio, A.; Salmon, E. D.: The spindle-assembly checkpoint in space and time. NATURE REVIEWS MOLECULAR CELL BIOLOGY 8 (5), S. 379 - 393 (2007)

Plyte, S.; Musacchio, A.: PLK1 inhibitors: Setting the mitotic death trap. CURRENT BIOLOGY 17 (8), S. R280 - R283 (2007)

DeLuca, J. G.; Gall, W. E.; Ciferri, C.; Cimini, D.; Musacchio, A.; Salmon, E. D.: Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. CELL 127 (5), S. 969 - 982 (2006)

Mapelli, M.; Filipp, F. V.; Rancati, G.; Massimiliano, L.; Nezi, L.; Stier, G.; Hagan, R. S.; Confalonieri, S.; Piatti, S.; Sattler, M. et al.; Musacchio, A.: Determinants of conformational dimerization of Mad2 and its inhibition by p31^comet. EMBO JOURNAL 25 (6), S. 1273 - 1284 (2006)

Nezi, L.; Rancati, G.; De Antoni, A.; Pasqualato, S.; Piatti, S.; Musacchio, A.: Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae. JOURNAL OF CELL BIOLOGY 174 (1), S. 39 - 51 (2006)

Penengo, L.; Mapelli, M.; Murachelli, A. G.; Confalonieri, S.; Magri, L.; Musacchio, A.; Di Fiore, P. P.; Polo, S.; Schneider, T. R.: Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. CELL 124 (6), S. 1183 - 1195 (2006)

Vink, M.; Simonetta, M.; Transidico, P.; Ferrari, K.; Mapelli, M.; De Antoni, A.; Massimiliano, L.; Ciliberto, A.; Faretta, M.; Salmon, E. D. et al.; Musacchio, A.: In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics. CURRENT BIOLOGY 16 (8), S. 755 - 766 (2006)

Ciferri, C.; De Luca, J.; Monzani, S.; Ferrari, K. J.; Ristic, D.; Wyman, C.; Stark, H.; Kilmartin, J.; Salmon, E. D.; Musacchio, A.: Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore. JOURNAL OF BIOLOGICAL CHEMISTRY 280 (32), S. 29088 - 29095 (2005)

De Antoni, A.; Pearson, C. G.; Cimini, D.; Canman, J. C.; Sala, V.; Nezi, L.; Mapelli, M.; Sironi, L.; Faretta, M.; Salmon, E. D. et al.; Musacchio, A.: The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. CURRENT BIOLOGY 15 (3), S. 214 - 225 (2005)

DeAntoni, A.; Sala, V.; Musacchio, A.: Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 360 (1455), S. 637 - 647 (2005)

Sessa, F.; Mapelli, M.; Ciferri, C.; Tarricone, C.; Areces, L. B.; Schneider, T. R.; Stukenberg, P. T.; Musacchio, A.: Mechanism of Aurora B activation by INCENP and inhibition by Hesperadin. MOLECULAR CELL 18 (3), S. 379 - 391 (2005)

Mapelli, M.; Musacchio, A.: The structural perspective on CDK5. NEUROSIGNALS 12 (4-5), S. 164 - 172 (2003)

Musacchio, A.; Hardwick, K. G.: The spindle checkpoint: Structural insights into dynamic signalling. NATURE REVIEWS MOLECULAR CELL BIOLOGY 3 (10), S. 731 - 741 (2002)

Sironi, L.; Mapelli, M.; Knapp, S.; De Antoni, A.; Jeang, K.-T.; Musacchio, A.: Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of 'safety belt' binding mechanism for the spindle checkpoint. EMBO JOURNAL 21 (10), S. 2496 - 2506 (2002)

Fraschini, R.; Beretta, A.; Sironi, L.; Musacchio, A.; Lucchini, G.; Piatti, S.: Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO JOURNAL 20 (23), S. 6648 - 6659 (2001)

Sironi, L.; Melixetian, M.; Faretta, M.; Prosperini, E.; Helin, K.; Musacchio, A.: Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for spindle checkpoint. EMBO JOURNAL 20 (22), S. 6371 - 6382 (2001)

Tarricone, C.; Dhavan, R.; Peng, J.; Areces, L. B.; Tsai, L.-H.; Musacchio, A.: Structure and regulation of the CDK5-p25^nck5a complex. MOLECULAR CELL 8 (3), S. 657 - 669 (2001)

Kang, H.; Freund, C.; Duke-Cohan, J. S.; Musacchio, A.; Wagner, G.; Rudd, C. E.: SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55. EMBO JOURNAL 19 (12), S. 2889 - 2899 (2000)

Orrico, A.; Galli, L.; Falciani, M.; Bracci, M.; Cavaliere, M. L.; Rinaldi, M. M.; Musacchio, A.; Sorrentino, V.: A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome). FEBS LETTERS 478 (3), S. 216 - 220 (2000)