1st international SPHIRE Workshop
The first international Workshop on the software suite SPHIRE took place from the 8th – 10th May 2017 at the Max Planck Institute of Molecular Physiology.
How pathogenic bacteria avoid being eaten by cells
Yaowen Wu, group leader at the Chemical Genomics Centre (CGC) of the Max Planck Society have unraveled how the Legionella bacteria outsmart the human body’s defense termed autophagy.
Human Frontier Science Program (HFSP) Grant awarded to Peter Bieling
The board of Trustees of HFSP has approved a Career Development Award for Pieter Bieling's project "The systems biochemistry of cell polarity and cytoskeletal morphogenesis". He will be awarded a total amount of 300,000 USD for 3 years.
Bieling Group >
Message in a living cell
The groups of Leif Dehmelt and Yaowen Wu (CGC) developed a new technique termed "Molecular Activity Painting" to study signal transduction at the plasma membrane.
Human Frontier Science Program (HFSP) Grant awarded to Heinz Neumann
Neumann‘s group is part of an international team that will be supported by the Human Frontier Science Program (HFSP) for the next three years. The plan is to use photochemical traps and high-resolution imaging to gain insights into the structure and function of transient chromatin complexes.
Neumann Group > HFSP Awards 2017 >
DivIDE - A new generation of molecular engineers
The MPI of Molecular Physiology is part of the DivIDE Network, a Marie Skłodowska-Curie actions training network funded by the European Commission’s H2020 Programme.
A question of balance
Missegregation of DNA during the cell division can lead to chromosomal instability (CIN), a characteristic of most human cancers. The Bird lab revealed a so far unknown mechanism that determines the fidelity of chromosome stability.
SPHIRE - Solving high resolution cryo-EM structures
SPHIRE is a new powerfull software suite designed for easy access to cryo electron microscopy with the clear goal of quality assessment and result reproducibility by statistical resampling. SPHIRE was developed by the Raunser Group and the Penczek Group (UTHealth) in a collaborative effort.
Yaowen Wu becomes Wallenberg Academy Fellow
The Knut and Alice Wallenberg Foundation and the Royal Swedish Academy of Sciences have selected Yaowen Wu as a young academy fellow. He will get a funding of 1.5 Million Euros over a five-year period and will be active at the Umeå University.
6th IMPRS Studenten Symposium
The title says it all: Interactions on all levels....interactions between students, group leaders, professors....interactions between biologists, chemists and physicists. We had a great IMPRS Student Symposium, with lots of interesting talks and lively discussions. A big thank you to the IMPRS students and coordinators!
Crucial component of cell division modeled
Andrea Musacchio and coworkers have analyzed and modelled the structure of the point of attachment of the chromosomes to the kinetochore. In the process, they have discovered how the different kinetochore proteins work together to bind the chromosomes securely to the microtubules.
Why is Usain Bolt the fastest man alive?
The group of Prof. Dr. Stefan Raunser has analyzed muscle proteins and observed the molecules at work at a previously unattained level of detail. Cryo-electron microscopy can be used to explain the cause of muscle diseases – and to identify features that make the musculature of top athletes so efficient.
Sharper than living matter permits
Philippe Bastiaens and coworkers have found a way to pinpoint the positions of individual molecules while at the same time measuring their activity and interactions in the same living cell. A dedicated cooling protocol on a microscope allows to pause cellular life at subzero temperatures, to let it continue to live again after warming. From the series of individual snapshots obtained, the researchers are able to form a precise spatial-temporal picture of the activity patterns of individual molecules within individual cells. More >
Björn Papke und Gunther Zimmermann awarde with the Otto Hahn Medal
As part of this year's annual meeting of the Max Planck Society, our fomer PhD students Björn Papke and Gunter Zimmermann were awarded with the Otto Hahn Medal for the development of a new approach to affect oncogenic Ras signalling by pharmacological interference. Currently, Björn is a postdoctoral fellow at the UNC Lineberger Comprehensive Cancer Center at The University of North Carolina at Chapel Hill. Gunther Zimmermann is a postdoctoral fellow at the ETH Zürich. More >