HFSP Grant awarded to Peter Bieling
10 new Lab Technician Trainees
How pathogenic bacteria avoid being eaten by cells
How bacteria puncture the membrane of insect cells
The Raunser lab reports the cryo-EM structure of the XaxAB pore complex from Xenorhabdus nematophila and the crystal structures of the soluble monomers of XaxA and XaxB.
Separating the wheat from the chaff in target identification for bioactive molecules
The Waldmann group developed a composite strategy, where chemical proteomics and in silico target prediction were successfully combined to identify 5-Lipoxygenase as the target of the Wnt pathway inhibitor Lipoxygenin.
Communicating the age of the actin cytoskeleton through conformational changes
The Raunser lab, for the first time, solved six high-resolution cryo-structures of F-actin in all its nucleotide states. The structures reveal how the state links to conformational dynamics and how this could determine interactions with actin binding proteins.
Zhi-Jun Jia and Katharina Overlack awarded with the Otto Hahn Medal
As part of this year's annual meeting of the Max Planck Society, our former PhD students Katharina Overlack and Zhi-Jun Jia were awarded with the Otto Hahn Medal for their outstanding scientific achievements.
4th international SPHIRE Workshop
The fourth international Workshop on the software suite SPHIRE took place from the 11th – 13th June 2017 at the Max Planck Institute of Molecular Physiology.
Great honour for former MPI Director Prof. Dr. Roger Goody
The former Max Planck Director Prof. Dr. Roger Goody became a Fellow of the Royal Society – the prestigious British Academy of Sciences. The Royal Society honours his extraordinary scientific work.
Stefan Raunser elected as EMBO Member
EMBO announces today that Prof. Dr. Stefan Raunser has been elected among 62 outstanding life scientists to its membership. He is joining a group of more than 1800 of the best researchers in Europe and around the world.
Eleven million euros for Dortmund alliance for the development of new lead compounds
Scientists from eight institutions combine their manifold expertise to develop an infrastructure for drug discovery in North Rhine-Westphalia.
AiCuris and MPI join forces in the field of anti-infectives
AiCuris Anti-infective Cures GmbH, a leading company in the discovery and development of innovative drugs targeting infectious diseases and the MPI have entered into a collaborative agreement to identify novel compounds for the treatment of viral and bacterial infections..
DFG Grant awarded to Alex Bird
The DFG has approved a Research Grant for Alex Bird’s project “Molecular basis of clathrin mediated stabilization of microtubules for chromosome segregation”.
Verena Kunig and Julian von der Ecken awarded by the TU Dortmund
Two former students from the Raunser lab where honored in this year’s Academic Graduation Ceremony at the TU Dortmund.
A sense of touch for cells
The Dehmelt and Nalbant (University Duisburg-Essen) labs identified a mechanism, by which human cells can squeeze the material they interact with, in order to probe its elastic properties.
Aneta Koseska receives Habilitation at TU Dortmund
Aneta Koseska now holds the qualification to teach at the TU Dortmund and gives the lecture "Dynamics of biological Networks" to students of Chemical Biology.
Nature as a Pharmacy
Bacteria, plants and animals are full of unknown substances that could be beneficial for humans. Herbert Waldmann tests natural products for their biological efficacy and tries to mimic their effects with simpler molecules.
10 new Lab Technician Trainees
This September ten new Lab Technician Trainees started their training in a unique training initiative of the TU Dortmund, ISAS and IfADo.
MPI researchers awarded with Dortmund Biomedicine Award
The “Verein zur Förderung der biomedizinischen und klinischen Forschung e.V.“ awarded four scientists from the Max Planck Institute (MPI) of Molecular Physiology at this year's Dortmund Biomedicine Summit on August 29th 2017.
Julian von der Ecken honoured with Otto Hahn Medal
During the 68th Annual Meeting of the MPG Julian von der Ecken was awarded the Otto Hahn Medal for young scientists for his structural investigation of key muscle proteins.
Herbert Waldmann receives Paul Karrer Medal
Prof. Dr. Dr. h.c. Herbert Waldmann delivered the 38th Paul Karrer Lecture.
Leif Dehmelt receives Heisenberg Stipend of the DFG
How cells organize their shape: Leif Dehmelt receives the Heisenberg Stipend of the Deutsche Forschungsgemeinschaft DFG.
1st international SPHIRE Workshop
The first international Workshop on the software suite SPHIRE took place from the 8th – 10th May 2017 at the Max Planck Institute of Molecular Physiology.
How pathogenic bacteria avoid being eaten by cells
Yaowen Wu, group leader at the Chemical Genomics Centre (CGC) of the Max Planck Society have unraveled how the Legionella bacteria outsmart the human body’s defense termed autophagy.
Human Frontier Science Program (HFSP) Grant awarded to Peter Bieling
The board of Trustees of HFSP has approved a Career Development Award for Pieter Bieling's project "The systems biochemistry of cell polarity and cytoskeletal morphogenesis". He will be awarded a total amount of 300,000 USD for 3 years.
Bieling Group >
Message in a living cell
The groups of Leif Dehmelt and Yaowen Wu (CGC) developed a new technique termed "Molecular Activity Painting" to study signal transduction at the plasma membrane.
Human Frontier Science Program (HFSP) Grant awarded to Heinz Neumann
Neumann‘s group is part of an international team that will be supported by the Human Frontier Science Program (HFSP) for the next three years. The plan is to use photochemical traps and high-resolution imaging to gain insights into the structure and function of transient chromatin complexes.
Neumann Group > HFSP Awards 2017 >
DivIDE - A new generation of molecular engineers
The MPI of Molecular Physiology is part of the DivIDE Network, a Marie Skłodowska-Curie actions training network funded by the European Commission’s H2020 Programme.
A question of balance
Missegregation of DNA during the cell division can lead to chromosomal instability (CIN), a characteristic of most human cancers. The Bird lab revealed a so far unknown mechanism that determines the fidelity of chromosome stability.
SPHIRE - Solving high resolution cryo-EM structures
SPHIRE is a new powerfull software suite designed for easy access to cryo electron microscopy with the clear goal of quality assessment and result reproducibility by statistical resampling. SPHIRE was developed by the Raunser Group and the Penczek Group (UTHealth) in a collaborative effort.
Yaowen Wu becomes Wallenberg Academy Fellow
The Knut and Alice Wallenberg Foundation and the Royal Swedish Academy of Sciences have selected Yaowen Wu as a young academy fellow. He will get a funding of 1.5 Million Euros over a five-year period and will be active at the Umeå University.
6th IMPRS Studenten Symposium
The title says it all: Interactions on all levels....interactions between students, group leaders, professors....interactions between biologists, chemists and physicists. We had a great IMPRS Student Symposium, with lots of interesting talks and lively discussions. A big thank you to the IMPRS students and coordinators!
Crucial component of cell division modeled
Andrea Musacchio and coworkers have analyzed and modelled the structure of the point of attachment of the chromosomes to the kinetochore. In the process, they have discovered how the different kinetochore proteins work together to bind the chromosomes securely to the microtubules.
Why is Usain Bolt the fastest man alive?
The group of Prof. Dr. Stefan Raunser has analyzed muscle proteins and observed the molecules at work at a previously unattained level of detail. Cryo-electron microscopy can be used to explain the cause of muscle diseases – and to identify features that make the musculature of top athletes so efficient.
Sharper than living matter permits
Philippe Bastiaens and coworkers have found a way to pinpoint the positions of individual molecules while at the same time measuring their activity and interactions in the same living cell. A dedicated cooling protocol on a microscope allows to pause cellular life at subzero temperatures, to let it continue to live again after warming. From the series of individual snapshots obtained, the researchers are able to form a precise spatial-temporal picture of the activity patterns of individual molecules within individual cells. More >
Björn Papke und Gunther Zimmermann awarde with the Otto Hahn Medal
As part of this year's annual meeting of the Max Planck Society, our former PhD students Björn Papke and Gunther Zimmermann were awarded with the Otto Hahn Medal for the development of a new approach to affect oncogenic Ras signalling by pharmacological interference. Currently, Björn is a postdoctoral fellow at the UNC Lineberger Comprehensive Cancer Center at The University of North Carolina at Chapel Hill. Gunther Zimmermann is a postdoctoral fellow at the ETH Zürich. More >