Publications of Roger S. Goody
All genres
Journal Article (181)
1.
Journal Article
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife (2023)
2.
Journal Article
13 (2022)
Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nature Communications 3.
Journal Article
The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie International Edition, pp. 1 - 27 (2022)
4.
Journal Article
The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie, pp. 1 - 27 (2022)
5.
Journal Article
11 (4187), 4187, pp. 1 - 16 (2020)
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. Nature Communications 6.
Journal Article
11 (7), pp. 760 - 770 (2020)
KRasG12C inhibitors in clinical trials: a short historical perspective. RSC Medicinal Chemistry 7.
Journal Article
26 (10), pp. 1338 - 1348 (2019)
Mutant-Specific Targeting of Ras G12C Activity by Covalently Reacting Small Molecules. Cell Chemical Biology 8.
Journal Article
Assays for Nucleotide Competitive Reversible and Irreversible Inhibitors of Ras GTPases. Biochemistry, pp. 1 - 10 (2018)
9.
Journal Article
F74, F74, pp. 315 - 321 (2018)
Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS 10.
Journal Article
129 (49), pp. 15943 - 15947 (2017)
Proximity-triggered covalent stabilization of low-affinity protein complexes in vitro and in vivo. Angewandte Chemie International Edition 11.
Journal Article
56 (49), pp. 15737 - 15741 (2017)
Proximity-triggered covalent stabilization of low-affinity protein complexes in vitro and in vivo. Angewandte Chemie 12.
Journal Article
7, 3687, pp. 1 - 11 (2017)
Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity. Scientific Reports 13.
Journal Article
398 (5-6), pp. 565 - 575 (2017)
Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport. Biological Chemistry 14.
Journal Article
Multivalency in Rab effector interactions. Small GTPases, pp. 1 - 7 (2017)
15.
Journal Article
Molecular control of Rab activity by GEFs, GAPs and GDI. Small GTPases, pp. 1 - 17 (2017)
16.
Journal Article
bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. eLife, pp. e18675:1 - e18675:49 (2016)
17.
Journal Article
11 (8), pp. 2375 - 2382 (2016)
Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chemical Biology 18.
Journal Article
105 (8), pp. 422 - 430 (2016)
Ras GTPases and myosin: qualitative conservation and quantitative diversification in signal and energy transduction. Biopolymers 19.
Journal Article
7 (2), pp. 93 - 106 (2016)
A pull-down procedure for the identification of unknown GEFs for small GTPases. Small GTPases 20.
Journal Article
6:7773, 7773, pp. 1 - 10 (2015)
Locking GTPases covalently in their functional states. Nature Communications