Publikationen von Slava Ziegler

Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie International Edition 57 (43), S. 14250 - 14254 (2018)

Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie 130 (43), S. 14446 - 14450 (2018)

Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), S. 1095 - 1106 (2018)

Sankar, M. G.; Roy, S.; Tran, T. T. N.; Wittstein, K.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Kumar, K.: Scaffold Diversity Synthesis Delivers Complex, Structurally, and Functionally Distinct Tetracyclic Benzopyrones. ChemistryOpen 7 (4), S. 302 - 309 (2018)

Pries, V.; Nöcker, C.; Khan, D.; Johnen, P.; Hong, Z.; Tripathi, A.; Keller, A.-L.; Fitz, M.; Perruccio, F.; Filipuzzi, I. et al.; Thavam, S.; Aust, T.; Riedl, R.; Ziegler, S.; Bono, F.; Schaaf, G.; Bankaitis, V. A.; Waldmann, H.; Hoepfner, D.: Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties. Cell Chemical Biology 25 (3), S. 279 - 290 (2018)

Höing, S.; Yeh, T.-Y.; Baumann, M.; Martinez, N. E.; Habenberger , P.; Kremer, L.; Drexler, H. C. A.; Küchler, P.; Reinhardt, P.; Choidas, A. et al.; Zischinsky, M.-L.; Zischinsky, G.; Nandini, S.; Ledray, A. P.; Ketcham, S. A.; Reinhardt, L.; Abo-Rady, M.; Glatza, M.; King, S. J.; Nussbaumer, P.; Ziegler, S.; Klebl, B.; Schroer, T. A.; Schöler, H. R.; Waldmann, H.; Sterneckert, J.: Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein. Cell Chemical Biology 25, S. 1 - 13 (2018)

Li, H.; Gontla, R.; Flegel, J.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie 131 (1), S. 313 - 317 (2018)

Wilke, J.; Kawamura, T.; Watanabe, N.; Osada, H.; Ziegler, S.; Waldmann, H.: Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion. Bioorganic & Medicinal Chemistry 26 (8), S. 1453 - 1461 (2017)

Kremer, L.; Schultz-Fademrecht, C.; Baumann, M.; Habenberger, P.; Choidas, A.; Klebl, B.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Ziegler, S. et al.; Schneider, G.; Waldmann, H.: Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction. Angewandte Chemie International Edition 56 (42), S. 13021 - 13025 (2017)

Sheremet, M.; Kapoor, S.; Schröder, P.; Kumar, K.; Ziegler, S.; Waldmann, H.: Small Molecules Inspired by the Natural Product Withanolides as Potent Inhibitors of Wnt Signaling. ChemBioChem: A European Journal of Chemical Biology 18 (18), S. 1797 - 1806 (2017)

Kremer, L.; Schultz-Fademrecht, C.; Baumann, M.; Habenberger, P.; Choidas, A.; Klebl, B.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Ziegler, S. et al.; Schneider, G.; Waldmann, H.: Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction. Angewandte Chemie 129, S. 1 - 6 (2017)

Küchler, P.; Zimmermann, G.; Winzker, M.; Janning, P.; Waldmann, H.; Ziegler, S.: Identification of novel PDEd interacting proteins. Bioorganic & Medicinal Chemistry 26 (8), S. 1426 - 1434 (2017)

Waldmann, H.; Martinez, N. E.; Zimmermann, T. J.; Goosmann, C.; Alexander, T.; Hedberg, C.; Ziegler, S.; Zychlinsky, A.: Tetrahydroisoquinolines: New Inhibitors of Neutrophil Extracellular Trap (NET) Formation. ChemBioChem: A European Journal of Chemical Biology 18 (10), S. 888 - 893 (2017)

Mejuch, T.; Garivet, G.; Hofer, W.; Kaiser, N.; Fansa, E. K.; Ehrt, C.; Koch, O.; Baumann , M.; Ziegler, S.; Wittinghofer, A. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC119–Cargo Interaction. Angewandte Chemie International Edition 56, S. 1 - 7 (2017)

Mejuch, T.; Garivet, G.; Hofer, W.; Kaiser, N.; Fansa, E. K.; Ehrt, C.; Koch, O.; Baumann, M.; Ziegler, S.; Wittinghofer, A. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC119–Cargo Interaction. Angewandte Chemie 129, S. 1 - 7 (2017)

Waldmann, H.; Förster, T.; Lopez Tosco, S.; Ziegler, S.; Antonchick, A. P.: Enantioselective Organocatalytic Synthesis of a Secoyohimbane-Inspired Compound Collection with Neuritogenic Activity. ChemBioChem: A European Journal of Chemical Biology, S. 1 - 11 (2017)

Tschapalda, K.; Zhang, Y.-Q.; Liu, L.; Golovnina, K.; Schlemper, T.; Eichmann, T. O.; Lal-Nag, M.; Sreenivasan, U.; McLenithan, J.; Ziegler, S. et al.; Sztalryd, C.; Lass, A.; Auld, D.; Oliver, B.; Waldmann, H.; Li, Z.; Shen, M.; Boxer, M. B.; Beller, M.: A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics. EBioMedicine 8, S. 49 - 59 (2016)

Illich, D. J.; Zhang, M.; Ursu, A.; Osorno, R.; Kim, K.-P.; Yoon, J.; Araúzo-Bravo, M. J.; Wu, G.; Esch, D.; Sabour, D. et al.; Colby, D.; Grassme, K. S.; Chen, J.; Greber, B.; Höing, S.; Herzog, W.; Ziegler, S.; Chambers, I.; Gao, S.; Waldmann, H.; Schöler, H. R.: Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Reports 15 (4), S. 787 - 800 (2016)

Schürmann, M.; Janning, P.; Ziegler, S.; Waldmann, H.: Small-Molecule Target Engagement in Cells. Cell Chemical Biology 23 (4), S. 435 - 441 (2016)

Ursu, A.; Illich, D. J.; Takemoto, Y.; Porfetye, A. T.; Zhang, M.; Brockmeyer, A.; Janning, P.; Watanabe, N.; Osada, H.; Vetter, I. R. et al.; Ziegler, S.; Schöler, H. R.; Waldmann, H.: Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chemical Biology 23 (4), S. 494 - 507 (2016)