Publikationen von Herbert Waldmann

Milroy, L.-G.; Rizzo, S.; Calderon, A.; Ellinger, B.; Erdmann, S.; Mondry, J.; Verveer, P.; Bastiaens, P.; Waldmann, H.; Dehmelt, L. et al.; Arndt, H.-D.: Selective Chemical Imaging of Static Actin in Live Cells. Journal of the American Chemical Society 134 (20), 1, S. 8480 - 8486 (2012)

Görmer, K.; Bürger, M.; Kruijtzer, J. A. W.; Vetter, I.; Vartak, N.; Brunsveld, L.; Bastiaens, P. I. H.; Liskamp, R. M. J.; Triola, G.; Waldmann, H.: Chemical-Biological Exploration of the Limits of the Ras De- and Repalmitoylating Machinery. ChemBioChem 13 (7), 1, S. 1017 - 1023 (2012)

Deraeve, C.; Guo, Z.; Bon, R. S.; Blankenfeldt, W.; DiLucrezia, R.; Wolf, A.; Menninger, S.; Stigter, E. A.; Wetzel, S.; Choidas, A. et al.; Alexandrov, K.; Waldmann, H.; Goody, R. S.; Wu, Y.-W.: Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase. Journal of the American Chemical Society 134 (17), 1, S. 7384 - 7391 (2012)

Das, D.; Tnimov, Z.; Nguyen, U. T. T.; Thimmaiah, G.; Lo, H.; Abankwa, D.; Wu, Y.; Goody, R. S.; Waldmann, H.; Alexandrov, K.: Flexible and General Synthesis of Functionalized Phosphoisoprenoids for the Study of Prenylation in vivo and in vitro. ChemBioChem 13 (5), 1, S. 674 - 683 (2012)

Samatov, T. R.; Wolf, A.; Odenwälder, P.; Bessonov, S.; Deraeve, C.; Bon, R. S.; Waldmann, H.; Lührmann, R.: Psoromic Acid Derivatives: A New Family of Small-Molecule Pre-mRNA Splicing Inhibitors Discovered by a Stage-Specific High-Throughput in Vitro Splicing Assay. ChemBioChem 13 (5), 1, S. 640 - 644 (2012)

Potowski, M.; Schürmann, M.; Preut, H.; Antonchick, A. P.; Waldmann, H.: Programmable enantioselective one-pot synthesis of molecules with eight stereocenters. Nature Chemical Biology 8, 1, S. 428 - 430 (2012)

Dückert, H.; Pries, V.; Khedkar, V.; Menninger, S.; Bruss, H.; Bird, A. W.; Maliga, Z.; Brockmeyer, A.; Janning, P.; Hyman, A. et al.; Grimme, S.; Schürmann, M.; Preut, H.; Hübel, K.; Ziegler, S.; Kumar, K.; Waldmann, H.: Natural product-inspired cascade synthesis yields modulators of centrosome integrity. Nature Chemical Biology 8 (2), 1, S. 179 - 184 (2012)

Xu, J.; Hedberg, C.; Dekker, F. J.; Li, Q.; Haigis, K. M.; Hwang, E.; Waldmann, H.; Shannon, K.: Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras. Blood 119 (4), 1, S. 1032 - 1035 (2012)

Kapoor, S.; Triola, G.; Vetter, I. R.; Erlkamp, M.; Waldmann, H.; Winter, R.: Revealing conformational substates of lipidated N-Ras protein by pressure modulation. Proceedings of the National Academy of Sciences of the USA 109 (2), 1, S. 460 - 465 (2012)

Bürger, M.; Zimmermann, T. J.; Kondoh, Y.; Stege, P.; Watanabe, N.; Osada, H.; Waldmann, H.; Vetter, I. R.: Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterase. Journal of Lipid Research 53 (1), 1, S. 43 - 50 (2012)

Triola, G.; Waldmann, H.; Hedberg, C.: Chemical Biology of Lipidated Proteins. ACS Chemical Biology 7 (1), 1, S. 87 - 99 (2012)

Antonchick, A. P.; Schuster, H.; Bruss, H.; Schürmann, M.; Preut, H.; Rauh, D.; Waldmann, H.: Enantioselective synthesis of the spirotryprostatin A scaffold. Tetrahedron 67 (52), 1, S. 10195 - 10202 (2011)

Wetzel, S.; Bon, R. S.; Kumar, K.; Waldmann, H.: Biology-Oriented Synthesis. Angewandte Chemie International Edition 50 (46), 1, S. 10800 - 10826 (2011)

Wetzel, S.; Bon, R. S.; Kumar, K.; Waldmann, H.: Biologie-orientierte Synthese (BIOS). Angewandte Chemie 123 (46), 1, S. 10990 - 11018 (2011)

Ismail, S. A.; Chen, Y.-X.; Rusinova, A.; Chandra, A.; Bierbaum, M.; Gremer, L.; Triola, G.; Waldmann, H.; Bastiaens, P. I. H.; Wittinghofer, A.: Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nature Chemical Biology 7, 1, S. 942 - 949 (2011)

Hedberg, C.; Dekker, F. J.; Rusch, M.; Renner, S.; Wetzel, S.; Vartak, N.; Gerding-Reimers, C.; Bon, R. S.; Bastiaens, P. I. H.; Waldmann, H.: Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design. Angewandte Chemie 123 (42), 1, S. 10006 - 10011 (2011)

Hedberg, C.; Dekker, F. J.; Rusch, M.; Renner, S.; Wetzel, S.; Vartak, N.; Gerding-Reimers, C.; Bon, R. S.; Bastiaens, P. I. H.; Waldmann, H.: Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design. Angewandte Chemie International Edition 50 (42), 1, S. 9832 - 9837 (2011)

Rusch, M.; Zimmermann, T. J.; Bürger, M.; Dekker, F. J.; Görmer, K.; Triola, G.; Brockmeyer, A.; Janning, P.; Böttcher, T.; Sieber, S. A. et al.; Vetter, I. R.; Hedberg, C.; Waldmann, H.: Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M. Angewandte Chemie 123 (42), 1, S. 10012 - 10016 (2011)

Rusch, M.; Zimmermann, T. J.; Bürger, M.; Dekker, F. J.; Görmer, K.; Triola, G.; Brockmeyer, A.; Janning, P.; Böttcher, T.; Sieber, S. A. et al.; Vetter, I. R.; Hedberg, C.; Waldmann, H.: Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M. Angewandte Chemie International Edition 50 (42), 1, S. 9838 - 9842 (2011)

Eberhardt, L.; Kumar, K.; Waldmann, H.: Exploring and exploiting biologically relevant chemical space. Current Drug Targets 12 (11), 1, S. 1531 - 1546 (2011)