Publikationen von Axel Pahl
Alle Typen
Zeitschriftenartikel (36)
1.
Zeitschriftenartikel
Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair. ChemBioChem: A European Journal of Chemical Biology (2023)
2.
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Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space. Angewandte Chemie, International Edition in English (2023)
3.
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Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity. Journal of Medicinal Chemistry (2023)
4.
Zeitschriftenartikel
14 (2023)
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway. Chemical Science 5.
Zeitschriftenartikel
Morphological subprofile analysis for bioactivity annotation of small molecules. Cell Chemical Biology (2023)
6.
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Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles. Angewandte Chemie, International Edition in English (2023)
7.
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Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp3-Rich Compounds With Distinct Phenotypic Effects. Chemistry – A European Journal (2023)
8.
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Identification of biologically diverse tetrahydronaphtalen-2-ols through the synthesis and phenotypic profiling of chemically diverse, estradiol-inspired compounds. ChemBioChem: A European Journal of Chemical Biology (2023)
9.
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Identification of Dihydroorotate Dehydrogenase Inhibitors using the Cell Painting Assay. ChemBioChem: A European Journal of Chemical Biology (2022)
10.
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Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry – A European Journal (2022)
11.
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Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, S. 1053 - 1064 (2022)
12.
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Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, S. 1 - 16 (2021)
13.
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28 (12), S. 1780 - 1794 (2021)
Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 14.
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61 (11), S. 5458 - 5468 (2021)
Pseudonatural Products Occur Frequently in Biologically Relevant Compounds. Journal of Chemical Information and Modeling 15.
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8 (19), e2102042, S. 1 - 10 (2021)
Synthesis of Indofulvin Pseudo-Natural Products Yields a New Autophagy Inhibitor Chemotype. Advanced Science 16.
Zeitschriftenartikel
60 (39), S. 21384 - 21395 (2021)
Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie International Edition 17.
Zeitschriftenartikel
133 (39), S. 21554 - 21565 (2021)
Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie 18.
Zeitschriftenartikel
9 (28), S. 9358 - 9368 (2021)
Reducing Environmental Pollution by Antibiotics through Design for Environmental Degradation. ACS Sustainable Chemistry & Engineering 19.
Zeitschriftenartikel
12 (1), 1883, S. 1 - 11 (2021)
Natural product fragment combination to performance-diverse pseudo-natural products. Nature Communications 20.
Zeitschriftenartikel
60 (9), S. 4648 - 4656 (2020)
Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie International Edition