Key Publications 2023

Exploiting π and Chalcogen Interactions for the β-Selective Glycosylation of Indoles through Glycal Conformational Distortion

Exploiting π and Chalcogen Interactions for the β-Selective Glycosylation of Indoles through Glycal Conformational Distortion

Loh Group. Angew Chem Ed Engl (2023) [mehr]
Structure and activation mechanism of the Makes caterpillars floppy 1 toxin

Structure and activation mechanism of the Makes caterpillars floppy 1 toxin

Raunser Group Nat Commun (2023) [mehr]
Cooperative Bifurcated Chalcogen Bonding and Hydrogen Bonding as Stereocontrolling Elements for Selective Strain-Release Septanosylation

Cooperative Bifurcated Chalcogen Bonding and Hydrogen Bonding as Stereocontrolling Elements for Selective Strain-Release Septanosylation

Loh Group. J. Am. Cehm. Soc. (2023) [mehr]
RZZ-Spindly and CENP-E form an integrated platform to recruit dynein to the kinetochore corona

RZZ-Spindly and CENP-E form an integrated platform to recruit dynein to the kinetochore corona

Musacchio Group. EMBO J (2023)  [mehr]
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Waldmann Group. Nat Commun (2023)  [mehr]
Structure of the native myosin filament in the relaxed cardiac sarcomere

Structure of the native myosin filament in the relaxed cardiac sarcomere

Raunser Group. Nature (2023) [mehr]
The modes of action of ion-channel-targeting neurotoxic insecticides: lessons from structural biology. 

The modes of action of ion-channel-targeting neurotoxic insecticides: lessons from structural biology. 

Raisch & Raunser Group.  Nat Struct Mol Biol. (2023) [mehr]
Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space

Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space

Waldmann Group. Angew Chem Int Ed Engl. (2023) [mehr]
Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments

Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments

Bieling & Raunser Group. Nat Struct Mol Biol. (2023) [mehr]
Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases

Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases

Gersch Group. JACS (2023) [mehr]
Structural basis of mRNA binding by the human FERRY Rab5 effector complex

Structural basis of mRNA binding by the human FERRY Rab5 effector complex

Raunser Group. Mol Cell (2023) [mehr]
Programming inactive RNA-binding small molecules into bioactive degraders

Programming inactive RNA-binding small molecules into bioactive degraders

Waldmann Group. Nature (2023) [mehr]
Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding

Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding

Musacchio Group. EMBO J (2023) [mehr]
TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining

TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining

Raunser Group. Nature Methods (2023) [mehr]
Structural Biochemistry of Muscle Contraction

Structural Biochemistry of Muscle Contraction

Wang Z, Raunser S. Annu Rev Biochem (2023) [mehr]
The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling.

The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling.

Bastiaens Group. EMBO J. (2023) [mehr]
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

Goody Group. Elife (2023) [mehr]
The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex

The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex

Musacchio Group. Nat Commun. (2023)
  [mehr]
Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles

Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles

Waldmann Group.  Angew Chem Int Ed Engl. (2023) [mehr]
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