Publikationen von Pablo Martín-Gago

Klein, C.; Truxius, D.; Vogel, H. A.; Harizanova, J.; Murarka, S.; Martín-Gago, P.; Bastiaens, P. I. H.: PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas. International Journal of Cancer, S. 1 - 36 (2018)

Martín-Gago, P.; Fansa, E. K.; Winzker, M.; Murarka, S.; Janning, P.; Schultz-Fademrecht, C.; Baumann, M.; Wittinghofer, A.; Waldmann, H.: Covalent Protein Labeling at Glutamic Acids. Cell chemical biology 24 (5), S. 589 - 597 (2017)

Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie International Edition 56 (9), S. 2423 - 2428 (2017)

Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6d-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie 129 (9), S. 2463 - 2468 (2017)

Martín-Gago, P.; Fansa, E. K.; Wittinghofer, A.; Waldmann, H.: Structure-based development of PDEδ inhibitors. Biological Chemistry 398 (5-6), S. 535 - 545 (2016)

Papke, B.; Murarka, S.; Vogel, H. A.; Martín-Gago, P.; Kovacevic, M.; Truxius, D.; Fansa, E. K.; Ismail, S.; Zimmermann, G.; Heinelt, K. et al.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.; Bastiaens, P. I. H.: Identification of pyrazolopyridazinones as PDEδ inhibitors. Nature Communications 7, 11360, S. 1 - 9 (2016)

Murarka, S.; Martín-Gago, P.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Fansa, E. K.; Ismail, S.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.: Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site. Chemistry – A European Journal 23 (25), S. 6083 - 6093 (2016)