Publikationen

Carnero Corrales, M. A.; Zinken, S.; Konstantinidis, G.; Rafehi, M.; Abdelrahman, A.; Wu, Y.-W.; Janning, P.; Müller, C. E.; Laraia, L.; Waldmann, H.: Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin. Cell Chemical Biology 28 (12), S. 1750 - 1757 (2021)

Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), S. 1780 - 1794 (2021)

Hübinger, J.; Grecco, H.; Masip, M.; Christmann, J.; Fuhr, G. R.; Bastiaens, P. I. H.: Ultrarapid cryo-arrest of living cells on a microscope enables multiscale imaging of out-of-equilibrium molecular patterns. Science Advances 7 (50), eabk0882, S. 1 - 13 (2021)

Raisch, T.; Brockmann, A.; Ebbinghaus-Kintscher, U.; Freigang, J.; Gutbrod, O.; Kubicek, J.; Maertens, B.; Hofnagel, O.; Raunser, S.: Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nature Communications 12 (1), 7164, S. 1 - 12 (2021)

Martin, I. M.; Aponte-Santamaría , C.; Schmidt, L.; Hedtfeld, M.; Iusupov, A.; Musacchio, A.; Gräter, F.: Phosphorylation tunes elongation propensity and cohesiveness of INCENP's intrinsically disordered region. Journal of Molecular Biology (London), 167387, S. 1 - 37 (2021)

Goebel, G. L.; Hohnen, L.; Borgelt, L.; Hommen, P.; Qiu, X.; Lightfoot , H.; Wu, P.: Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the ProteineRNA interaction of LIN28elet-7. European Journal of Medicinal Chemistry 228, 114014, S. 1 - 14 (2021)

Song, X.; Conti, D.; Shrestha, R. L.; Braun, D.; Draviam, V. M.: Counteraction between Astrin-PP1 and Cyclin-BCDK1 pathways protects chromosome-microtubule attachments independent of biorientation. Nature Communications 12 (1), 7010, S. 1 - 16 (2021)

Saha, S.; Chen, Y.-T.; Ganta, S.; Gilles , M.; Holzapfel, B.; Lill, P.; Rehaga, H.; Gatsogiannis, C.; Clever, G. H.: Coordination cage-based emulsifiers: templated formation of metal oxide microcapsules monitored by in situ LC-TEM. Chemistry – A European Journal, S. 1 - 8 (2021)

van den Boom, J.; Kueck, A. F.; Kravic, B.; Müschenborn, H.; Giesing, M.; Pan, D.; Kaschani, F.; Kaiser, M.; Musacchio, A.; Meyer, H.: Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly. Nature Structural and Molecular Biology, S. 1 - 18 (2021)

Pospich, S.; Sweeney, H. L.; Houdusse, A.; Raunser, S.: High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. eLife 10, e73724, S. 1 - 81 (2021)

Huis in´t Veld, P. J.; Wohlgemuth, S.; Koerner, C.; Müller, F.; Janning, P.; Musacchio, A.: Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes. Protein Science, S. 1 - 25 (2021)

Belyy, A.; Merino, F.; Mechold, U.; Raunser, S.: Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nature Communications 12 (1), 6628, S. 1 - 9 (2021)

Hui, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.: Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines. Journal of the American Chemical Society, S. 1 - 7 (2021)

Heinrich, S.; Grote, M.; Sievers, S.; Kushnir, S.; Schulz, F.: Polyether Cyclization Cascade Alterations in Response to Monensin Polyketide Synthase Mutations. Chembiochem 22, S. 1 - 9 (2021)

Carrillo García, C.; Becker, C.; Forster, M.; Lohmann, S.; Freitag, P.; Laufer, S.; Sievers, S.; Fleischmann, B. K.; Hesse, M.; Schade, D.: High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation. Journal of Medicinal Chemistry, S. 1 - 20 (2021)