Publikationen

Krzyzanowski, A.; Esser, L. M.; Willaume, A.; Prudent, R.; `T Hart, P.; Waldmann, H.: Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors. European Journal of Medicinal Chemistry (2022)

d'Amico, E.; Ud Din Ahmad, M.; Cmentowski, V.; Girbig, M.; Müller, F.; Wohlgemuth, S.; Brockmeyer, A.; Maffini, S.; Vetter, I. R.; Carter, A. P. et al.; Perrakis, A.; Musacchio, A.: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. The Journal of Cell Biology: JCB 221 (2022)

Boltje, D. B.; Hoogenboom, J. P.; Jakobi, A. J.; Jensen, G. J.; Jonker, C. T.H.; Kaag, M. J.; Koster, A. J.; Last, M. G.F.; de Agrela Pinto, C.; Plitzko, J. M. et al.; Raunser, S.; Tacke, S.; Wang, Z.; van der Wee, E. B.; Wepf, R.; den Hoedt, S.: A cryogenic, coincident fluorescence, electron and ion beam microscope. eLife (2022)

Oosterheert, W.; Klink, B. U.; Belyy, A.; Pospich, S.; Raunser, S.: Structural Basis of actin filament assembly and aging. Nature (2022)

Young, R.; Flitsch, S.; Grigalunas, M.; Leeson, P.; Quinn, R.; Turner, N.; Waldmann, H.: The Time and Place for Nature in Drug Discovery. Journal of the American Chemical Society 2 (11) (2022)

Grethe, C.; Schmidt, M.; Kipka, G.-M.; O'Dea, R.; Gallant, K.; Janning, P.; Gersch, M.: Structural basis for specific inhibition of the deubiquitinase UCHL1. Nature Communications 13 (2022)

Schwietert, F.; Volkov, V. A.; Huis in´t Veld, P. J.; Dogterom, M.; Musacchio, A.; Kierfeld, J.: Strain stiffening of Ndc80 complexes attached to microtubule plus ends. Biophysical Journal (2022)

Schölermann, B.; Bonowski, J.; Grigalunas, M.; Burhop, A.; Xie, Y.; Hook, J.; Liu, J.; Nelson, A.; Dow, M.; Nowak, C. et al.; Pahl, A.; Sievers, S.; Ziegler, S.: Identification of Dihydroorotate Dehydrogenase Inhibitors using the Cell Painting Assay. ChemBioChem: A European Journal of Chemical Biology (2022)

Grigalunas, M.; Patil, S.; Krzyzanowski, A.; Pahl, A.; Flegel, J.; Schölermann, B.; Xie, J.; Sievers, S.; Ziegler, S.; Waldmann, H.: Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry – A European Journal (2022)

Davies, C.; Dötsch, L.; Ciulla, M. G.; Hennes, E.; Yoshida, K.; Gasper, R.; Scheel, R.; Sievers, S.; Strohmann, C.; Kumar, K. et al.; Ziegler, S.; Waldmann, H.: Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angewandte Chemie, International Edition in English (2022)

Rai, A.; Singh, A. K.; Bleimling, N.; Posern, G.; Vetter, I. R.; Goody, R. S.: Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nature Communications 13 (2022)

Belyy, A.; Lindemann, F.; Roderer, D.; Funk, J.; Bardiaux, B.; Protze, J.; Bieling, P.; Oschkinat, H.; Raunser, S.: Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin. Nature Communications 13 (2022)

Celestino, R.; Gama, J. B.; Castro-Rodrigues, A. F.; Barbosa, D. B.; Rocha, H.; d'Amico, E.; Musacchio, A.; Carvalho, A. X.; Morais-Cabral, J. H.; Gassmann, R.: JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport. The Journal of Cell Biology: JCB (2022)

Li, T.-D.; Bieling, P.; Weichsel, J.; Mullins, R. D.; Fletcher , D. A.: The molecular mechanism of load adaptation by branched actin networks. eLife (2022)

Akhilesh, N.; Abishek , D.; Robert , L.; Koseska, A.: Cells use molecular working memory to navigate inchanging chemoattractant fields. eLife (2022)