Publikationen von Slava Ziegler

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie International Edition, S. 1 - 27 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie, S. 1 - 27 (2022)

Akbarzadeh, M.; Deipenwisch, I.; Schoelermann, B.; Pahl, A.; Sievers, S.; Ziegler, S.; Waldmann, H.: Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, S. 1 - 16 (2021)

Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), S. 1780 - 1794 (2021)

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell‐Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie International Edition 60 (18), S. 9869 - 9874 (2021)

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell-Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie 133 (18), S. 9957 - 9962 (2021)

Ziegler, S.; Sievers, S.; Waldmann, H.: Morphological profiling of small molecules. Cell Chemical Biology 28 (3), S. 300 - 319 (2021)

Wilke, J.; Kawamura, T.; Xu, H.; Brause, A.; Friese, A.; Metz, M.; Schepmann, D.; Wünsch, B.; Artacho-Cordón, A.; Nieto, F. R. et al.; Watanabe, N.; Osada, H.; Ziegler, S.; Waldmann, H.: Discovery of a σ 1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling. Cell Chemical Biology 28, S. 1 - 13 (2021)

Schneidewind, T.; Brause, A.; Pahl, A.; Burhop, A.; Mejuch, T.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological profiling enables the identification of common mode of action for small molecules with different targets. Chembiochem 21 (22), S. 3197 - 3207 (2020)

Kawamura, T.; Futamura, Y.; Shang, E.; Muroi , M.; Janning, P.; Ueno, M.; Wilke, J.; Takeda, S.; Kondoh , Y.; Ziegler, S. et al.; Watanabe , N.; Waldmann, H.; Osada , H.: Discovery of small-molecule modulator of heterotrimeric G i-protein by integrated phenotypic profiling and chemical proteomics. BioScience, Biotechnology & Biochemistry, S. 1 - 7 (2020)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEδ targeting PROTAC that impairs lipid metabolism. Angewandte Chemie, International Edition 59 (14), S. 5595 - 5601 (2019)

Zimmermann, S.; Akbarzadeh, M.; Otte, F.; Strohmann, C.; Sankar, M. G.; Ziegler, S.; Pahl, A.; Sievers, S.; Kumar, K.: A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides. Chemistry – A European Journal 25, S. 1 - 7 (2019)

Reckzeh, E. S.; Karageorgis, G.; Schwalfenberg, M.; Ceballos, J.; Nowacki, J.; Stroet, M. C.M.; Binici, A.; Knauer, L.; Brand, S.; Choidas, A. et al.; Strohmann, C.; Ziegler, S.; Waldmann, H.: Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth. Cell Chemical Biology 26, S. 1 - 41 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, S. 1 - 28 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3. Angewandte Chemie, S. 1 - 28 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi, H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, International Edition, S. 1 - 37 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi , H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, S. 1 - 37 (2019)

Furuta, T.; Mizukami, Y.; Asano, L.; Kotake, K.; Ziegler, S.; Yoshida, H.; Watanabe, M.; Sato, S.-i.; Waldmann, H.; Nishikawa, M. et al.; Uesugi, M.: Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators. ACS Chemical Biology, S. 1 - 6 (2019)

Laraia, L.; Friese, A.; Corkery, D. P.; Konstantinidis, G.; Erwin, N.; Hofer, W.; Karatas, H.; Klewer, L.; Brockmeyer, A.; Metz, M. et al.; Schölermann, B.; Dwivedi, M.; Li, L.; Rios-Munoz, P.; Köhn, M.; Winter, R.; Vetter, I. R.; Ziegler, S.; Janning, P.; Wu, Y.-W.; Waldmann, H.: The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature Chemical Biology 15 (7), S. 710 - 720 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie International Edition, S. 1 - 14 (2019)