Publikationen von Slava Ziegler

Voigt, T.; Gerding-Reimers, C.; Tran, T. T. N.; Bergmann, S.; Lachance, H.; Schölermann, B.; Brockmeyer, A.; Janning, P.; Ziegler, S.; Waldmann, H.: A Natural Product Inspired Tetrahydropyran Collection Yields Mitosis Modulators that Synergistically Target CSE1L and Tubulin. Angewandte Chemie 125 (1), S. 428 - 432 (2013)

Matcha, K.; Madduri, A. V. R.; Roy, S.; Ziegler, S.; Waldmann, H.; Hirsch, A. K. H.; Minnaard, A. J.: Total Synthesis of ( -)-Doliculide, Structure–Activity Relationship Studies and Its Binding to F-Actin. ChemBioChem 13 (17), 1, S. 2537 - 2548 (2012)

Dückert, H.; Pries, V.; Khedkar, V.; Menninger, S.; Bruss, H.; Bird, A. W.; Maliga, Z.; Brockmeyer, A.; Janning, P.; Hyman, A. et al.; Grimme, S.; Schürmann, M.; Preut, H.; Hübel, K.; Ziegler, S.; Kumar, K.; Waldmann, H.: Natural product-inspired cascade synthesis yields modulators of centrosome integrity. Nature Chemical Biology 8 (2), 1, S. 179 - 184 (2012)

Radtke, L.; Willot, M.; Sun, H.; Ziegler, S.; Sauerland, S.; Strohmann, C.; Fröhlich, R.; Habenberger, P.; Waldmann, H.; Christmann, M.: Total Synthesis and Biological Evaluation of (-)Englerin A und B: Synthesis of Analogues with Improved Activity Profile. Angewandte Chemie International Edition 50 (17), 1, S. 3998 - 4002 (2011)

Radtke, L.; Willot, M.; Sun, H.; Ziegler, S.; Sauerland, S.; Strohmann, C.; Fröhlich, R.; Habenberger, P.; Waldmann, H.; Christmann, M.: Total Synthesis and Biological Evaluation of (-)Englerin A and B: Synthesis of Analogues with Improved Activity Profile. Angewandte Chemie 123 (17), 1, S. 4084 - 4088 (2011)

Antonchick, A. P.; Gerding-Reimers, C.; Catarinella, M.; Schürmann, M.; Preut, H.; Ziegler, S.; Rauh, D.; Waldmann, H.: Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products. Nature Chemistry 2 (9), 1, S. 735 - 740 (2010)

Röhrs, S.; Kutzner, N.; Vlad, A.; Grunwald, T.; Ziegler, S.; Müller, O.: Chronological expression of Wnt target genes Ccnd1, Myc, Cdkn1a, Tfrc, Plfl and Ramp3. Cell Biology International 33 (4), 1, S. 501 - 508 (2009)

Ziegler, S.; Röhrs, S.; Tickenbrock, L.; Langerak, A.; Chu, S.-T.; Feldmann, I.; Jakubowski, N.; Müller, O.: Lipocalin 24p3 is regulated by the Wnt pathway independent of regulation by iron. Cancer Genetics and Cytogenetics 174 (1), 1, S. 16 - 23 (2007)

Ziegler, S.; Röhrs, S.; Tickenbrock, L.; Möröy, T.; Klein-Hitpass, L.; Vetter, I. R.; Müller, O.: Novel target genes of the Wnt pathway and statistical insights into Wnt target promoter regulation. FEBS Journal 272 (7), 1, S. 1600 - 1615 (2005)

Chtarbova, S.; Müller, O.: Eine Frage zu Krebs? Die Antwort weiß nur der Wnt Signalweg. BIOspektrum 9 (6), 1, S. 701 - 703 (2003)

Chtarbova, S.; Nimmrich, I.; Erdmann, S.; Herter, P.; Renner, M.; Kitajewski, J.; Müller, O.: Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from β-catenin activation. Biochemical Journal 367, 1, S. 723 - 728 (2002)

Karaguni, I.-M.; Herter, P.; Debruyne, P.; Chtarbova, S.; Kasprzynski, A.; Herbrand, U.; Ahmadian, M. R.; Glüsenkamp, K.-H.; Winde, G.; Mareel, M. et al.; Möröy, T.; Müller, O.: The new Sulindac derivative IND 12 reverses Ras-induced cell transformation. Cancer Research 62 (6), 1, S. 1718 - 1723 (2002)

Vendrell Navarro, G.; Brockmeyer, A.; Waldmann, H.; Janning, P.; Ziegler, S.: Identification of the targets of biologically active small molecules using quantitative proteomics. In: Chemical Biology. Methods and Protocols Methods in Molecular Biology, Vol. 1263, Chap. 21, S. 263 - 286. Springer, New York (2015)

Kumar, K.; Ziegler, S.: Identification of the Targets of Natural-Product-Inspired Mitotic Inhibitors. In: Concepts and Case Studies in Chemical Biology, Chapter 16, S. 231 - 248 (Hg. Waldmann, H.; Janning, P.). Wiley-VCH, Weinheim (2014)

Ziegler, S.; Waldmann, H.: Hunting the Targets of Natural Product-Inspired Compounds. In: Chembiomolecular Science: At the Frontier of Chemistry and Biology, S. 229 - 238 (Hg. Shibasaki, M.; Iino, M.; Osada, H.). Springer Japan, Tokyo (2013)

Wada, A.; Kato, N.; Ziegler, S.: Joint Knowledge and Technology for Systems Chemical Biology. 2nd Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Wako, Japan, 15. April 2013 - 17. April 2013. ChemBioChem 2013 (14), S. 1504 - 1506 (2013)

Tran, T. T. N.: Evaluation of the phage display protocol for target identification of small molecules. Identification and characterization of mitosis modulators. Dissertation, Technische Universität Dortmund, Fakultät für Chemie, Dortmund (2014)

Ziegler, S.: Identifizierung und Charakterisierung neuer tumorrelevanter Gene, die unter Kontrolle des Wnt/β-Catenin-Signalwegs stehen. Dissertation, Ruhr-Universität, Bochum (2004)

Chtarbova, S.: Charakterisierung von Wnt-aktivierten Genen und ihren Produkten. Diplom, Ruhr-Universität, Bochum (2000)

Hübecker, M.: Identification and Characterisation of New Inhibitors of the Kinesins HSET and Eg5. Master, Universität Duisburg-Essen, Essen (2014)