Publikationen von Jana Flegel

Zeitschriftenartikel (13)

Zeitschriftenartikel
Liu, J.; Flegel, J.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie International Edition 60 (39), S. 21384 - 21395 (2021)
Zeitschriftenartikel
Liu, J.; Flegel, J.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie 133 (39), S. 21554 - 21565 (2021)
Zeitschriftenartikel
Rehan, M.; Flegel, J.; Heitkamp, F.; Pergomet, J. L.; Otte, F.; Strohmann, C.; Kumar, K.: Asymmetric Synthesis of 3,3 '-Piperidinoyl Spirooxindoles and Discovery of Stereospecific Cycloadducts as Novel Hedgehog Pathway Modulators. Synthesis 52 (21), S. 3140 - 3152 (2020)
Zeitschriftenartikel
Shaaban, S.; Davies, C.; Merten, C.; Flegel, J.; Otte, F.; Strohmann, C.; Waldmann, H.: Rh(III)-catalyzed C-H Activation of Aryl-Hydroxamates for the Synthesis of Isoindolinones. Chemistry – A European Journal 26 (47), S. 10729 - 10734 (2020)
Zeitschriftenartikel
Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi , H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, S. 1 - 37 (2019)
Zeitschriftenartikel
Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi, H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, International Edition, S. 1 - 37 (2019)
Zeitschriftenartikel
Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie International Edition 58 (4), S. 1062 - 1066 (2019)
Zeitschriftenartikel
Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie 131 (4), S. 1074 - 1078 (2019)
Zeitschriftenartikel
Li, H.; Gontla, R.; Flegel, J.; Merten , C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie International Edition 58 (1), S. 307 - 311 (2018)
Zeitschriftenartikel
Xin, X.; Zimmermann, S.; Flegel, J.; Otte, F.; Knauer, L.; Strohmann, C.; Ziegler, S.; Kumar, K.: Unravelling Synthesis and Chemistry of Stable, Acyclic and Double-Deficient 1,3-Butadienes: An endo-selective Diels-Alder Route to Hedgehog Pathway Inhibitors. Chemistry – A European Journal 25 (11), S. 2717 - 2722 (2018)
Zeitschriftenartikel
Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie International Edition 57 (43), S. 14250 - 14254 (2018)
Zeitschriftenartikel
Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie 130 (43), S. 14446 - 14450 (2018)
Zeitschriftenartikel
Li, H.; Gontla, R.; Flegel, J.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie 131 (1), S. 313 - 317 (2018)
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