Publikationen von Axel Pahl

Zeitschriftenartikel (27)

Zeitschriftenartikel
Schölermann, B.; Bonowski, J.; Grigalunas, M.; Burhop, A.; Xie, Y.; Hook, J.; Liu, J.; Nelson, A.; Dow, M.; Nowak, C. et al.; Pahl, A.; Sievers, S.; Ziegler, S.: Identification of Dihydroorotate Dehydrogenase Inhibitors using the Cell Painting Assay. ChemBioChem: A European Journal of Chemical Biology (2022)
Zeitschriftenartikel
Grigalunas, M.; Patil, S.; Krzyzanowski, A.; Pahl, A.; Flegel, J.; Schölermann, B.; Xie, J.; Sievers, S.; Ziegler, S.; Waldmann, H.: Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry – A European Journal (2022)
Zeitschriftenartikel
Akbarzadeh, M.; Deipenwisch, I.; Schoelermann, B.; Pahl, A.; Sievers, S.; Ziegler, S.; Waldmann, H.: Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, S. 1 - 16 (2021)
Zeitschriftenartikel
Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), S. 1780 - 1794 (2021)
Zeitschriftenartikel
Gally, J.-M.; Pahl, A.; Czodrowski, P.; Waldmann, H.: Pseudonatural Products Occur Frequently in Biologically Relevant Compounds. Journal of Chemical Information and Modeling 61 (11), S. 5458 - 5468 (2021)
Zeitschriftenartikel
Burhop, A.; Bag, S.; Grigalunas, M.; Woitalla, S.; Bodenbinder, P.-J.; Brieger, L.; Strohmann, C.; Pahl, A.; Sievers, S.; Waldmann, H.: Synthesis of Indofulvin Pseudo-Natural Products Yields a New Autophagy Inhibitor Chemotype. Advanced Science 8 (19), e2102042, S. 1 - 10 (2021)
Zeitschriftenartikel
Liu, J.; Flegel, J.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie International Edition 60 (39), S. 21384 - 21395 (2021)
Zeitschriftenartikel
Liu, J.; Flegel, J.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids. Angewandte Chemie 133 (39), S. 21554 - 21565 (2021)
Zeitschriftenartikel
Leder, C.; Suk, M.; Lorenz, S.; Rastogi, T.; Peifer, C.; Kietzmann, M.; Jonas, D.; Buck, M.; Pahl, A.; Kümmerer, K.: Reducing Environmental Pollution by Antibiotics through Design for Environmental Degradation. ACS Sustainable Chemistry & Engineering 9 (28), S. 9358 - 9368 (2021)
Zeitschriftenartikel
Grigalunas, M.; Burhop, A.; Zinken, S.; Pahl, A.; Gally, J.-M.; Wild, N.; Mantel, Y.; Sievers, S.; Foley, D. J.; Scheel, R. et al.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Natural product fragment combination to performance-diverse pseudo-natural products. Nature Communications 12 (1), 1883, S. 1 - 11 (2021)
Zeitschriftenartikel
Liu, J.; Cremosnik, G. S.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie International Edition 60 (9), S. 4648 - 4656 (2020)
Zeitschriftenartikel
Schneidewind, T.; Brause, A.; Pahl, A.; Burhop, A.; Mejuch, T.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological profiling enables the identification of common mode of action for small molecules with different targets. Chembiochem 21 (22), S. 3197 - 3207 (2020)
Zeitschriftenartikel
Liu, J.; Cremosnik, G. S.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie 133 (9), S. 4698 - 4706 (2020)
Zeitschriftenartikel
Karatas, H.; Akbarzadeh, M.; Adihou, H.; Hahne, G.; Pobbati, A. V.; Yihui Ng, E.; Guéret, S. M.; Sievers, S.; Pahl, A.; Metz, M. et al.; Zinken, S.; Dötsch, L.; Nowak, C.; Thavam, S.; Friese, A.; Kang, C.; Hong, W.; Waldmann, H.: Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket. Journal of Medicinal Chemistry 63 (20), S. 11972 - 11989 (2020)
Zeitschriftenartikel
Foley, D. J.; Zinken, S.; Corkery, D.; Laraia, L.; Pahl, A.; Wu, Y.-W.; Waldmann, H.: Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor. Angewandte Chemie, International Edition 59 (11), S. 1 - 17 (2020)
Zeitschriftenartikel
Foley, D. J.; Zinken, S.; Corkery, D.; Laraia, L.; Pahl, A.; Wu, Y.-W.; Waldmann, H.: Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor. Angewandte Chemie 132 (11), S. 1 - 17 (2020)
Zeitschriftenartikel
Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), S. 5721 - 5729 (2019)
Zeitschriftenartikel
Pobbati, A. V.; Mejuch, T.; Chakraborty, S.; Karatas, H.; Bharath, S. R.; Guéret, S. M.; Goy, P.-A.; Hahne, G.; Pahl, A.; Sievers, S. et al.; Guccione, E.; Song, H.; Waldmann, H.; Hong, W.: Identification of Quinolinols as Activators of TEAD-dependent Transcription. ACS Chemical Biology, S. 1 - 35 (2019)
Zeitschriftenartikel
Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), S. 5770 - 5778 (2019)
Zeitschriftenartikel
Zimmermann, S.; Akbarzadeh, M.; Otte, F.; Strohmann, C.; Sankar, M. G.; Ziegler, S.; Pahl, A.; Sievers, S.; Kumar, K.: A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides. Chemistry – A European Journal 25, S. 1 - 7 (2019)
Zur Redakteursansicht