Publikationen von Roger S. Goody

Zeitschriftenartikel (177)

Zeitschriftenartikel
Rai, A.; Bleimling, N.; Vetter, I. R.; Goody, R. S.: The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. Nature Communications 11 (4187), 4187, S. 1 - 16 (2020)
Zeitschriftenartikel
Goebel, L.; Müller, M. P.; Goody, R. S.; Rauh, D.: KRasG12C inhibitors in clinical trials: a short historical perspective. RSC Medicinal Chemistry 11 (7), S. 760 - 770 (2020)
Zeitschriftenartikel
Goody, R. S.; Müller, M. P.; Rauh, D.: Mutant-Specific Targeting of Ras G12C Activity by Covalently Reacting Small Molecules. Cell Chemical Biology 26 (10), S. 1338 - 1348 (2019)
Zeitschriftenartikel
Jeganathan, S.; Müller, M. P.; Imtiaz, A.; Goody, R. S.: Assays for Nucleotide Competitive Reversible and Irreversible Inhibitors of Ras GTPases. Biochemistry, S. 1 - 10 (2018)
Zeitschriftenartikel
Imtiaz, A.; Eu, S.; Koch, D.; Bleimling, N.; Goody, R. S.; Müller, M. P.: Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS F74, F74, S. 315 - 321 (2018)
Zeitschriftenartikel
Cigler, M.; Müller, T. G.; Horn-Ghetko, D.; von Wrisberg, M.-K.; Fottner, M.; Goody, R. S.; Itzen, A.; Müller, M. P.; Lang, K.: Proximity-triggered covalent stabilization of low-affinity protein complexes in vitro and in vivo. Angewandte Chemie International Edition 129 (49), S. 15943 - 15947 (2017)
Zeitschriftenartikel
Cigler, M.; Müller, T. G.; Horn-Ghetko, D.; von Wrisberg, M.-K.; Fottner, M.; Goody, R. S.; Itzen, A.; Müller, M. P.; Lang, K.: Proximity-triggered covalent stabilization of low-affinity protein complexes in vitro and in vivo. Angewandte Chemie 56 (49), S. 15737 - 15741 (2017)
Zeitschriftenartikel
Müller, M.; Jeganathan, S.; Heidrich, A.; Campos, J.; Goody, R. S.: Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity. Scientific Reports 7, 3687, S. 1 - 11 (2017)
Zeitschriftenartikel
Goody, R. S.; Müller, M. P.; Wu, Y.-W.: Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport. Biological Chemistry 398 (5-6), S. 565 - 575 (2017)
Zeitschriftenartikel
Rai, A.; Goody, R. S.; Müller, M. P.: Multivalency in Rab effector interactions. Small GTPases, S. 1 - 7 (2017)
Zeitschriftenartikel
Müller, M. P.; Goody, R. S.: Molecular control of Rab activity by GEFs, GAPs and GDI. Small GTPases, S. 1 - 17 (2017)
Zeitschriftenartikel
Rai, A.; Oprisko, A.; Campos, J.; Fu, Y.; Friese, T.; Itzen, A.; Goody, R. S.; Gazdag, E. M.; Müller, M.: bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. eLife, S. e18675:1 - e18675:49 (2016)
Zeitschriftenartikel
Cromm, P. M.; Spiegel, J.; Küchler, P.; Dietrich, L.; Kriegesmann, J.; Wendt, M.; Goody, R. S.; Waldmann, H.; Grossmann, T.: Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chemical Biology 11 (8), S. 2375 - 2382 (2016)
Zeitschriftenartikel
Müller, M. P.; Goody, R. S.: Ras GTPases and myosin: qualitative conservation and quantitative diversification in signal and energy transduction. Biopolymers 105 (8), S. 422 - 430 (2016)
Zeitschriftenartikel
Koch, D.; Rai, A.; Imtiaz, A.; Bleimling, N.; Friese, T.; Brockmeyer, A.; Janning, P.; Goud, B.; Itzen, A.; Müller, M. P. et al.; Goody, R. S.: A pull-down procedure for the identification of unknown GEFs for small GTPases. Small GTPases 7 (2), S. 93 - 106 (2016)
Zeitschriftenartikel
Wiegandt, D.; Vieweg, S.; Hofmann, F.; Koch, D.; Li, F.; Wu, Y.-W.; Itzen, A.; Müller, M. P.; Goody, R. S.: Locking GTPases covalently in their functional states. Nature Communications 6:7773, 7773, S. 1 - 10 (2015)
Zeitschriftenartikel
Gazdag, E. M.; Schöbel, S.; Shkumatov, A. V.; Goody, R. S.; Itzen, A.: The structure of the N-terminal domain of the Legionella protein SidC. Journal of Structural Biology 186 (1), S. 188 - 194 (2014)
Zeitschriftenartikel
Spiegel, J.; Cromm, P. M.; Itzen, A.; Goody, R. S.; Großmann, T.; Waldmann, H.: Direct Targeting of Rab-GTPase-Effector Interactions. Angewandte Chemie International Edition 53 (9), S. 2498 - 2503 (2014)
Zeitschriftenartikel
Spiegel, J.; Cromm, P. M.; Itzen, A.; Goody, R. S.; Großmann, T.; Waldmann, H.: Direkte Modulation von Rab-GTPase-Effektor-Wechselwirkungen. Angewandte Chemie 126 (9), S. 2531 - 2536 (2014)
Zeitschriftenartikel
Li, F.; Yi, L.; Zhao, L.; Itzen, A.; Goody, R. S.; Wu, Y.-W.: The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting. Proceedings of the National Academy of Sciences of the United States of America 111 (7), S. 2572 - 2577 (2014)
Zur Redakteursansicht