Publikationen von Tom Großmann

Zeitschriftenartikel (36)

Zeitschriftenartikel
Jeganathan, S.; Wendt, M.; Kiehstaller, S.; Brancaccio, D.; Kuepper, A.; Pospiech, N.; Carotenuto, A.; Novellino, E.; Hennig, S.; Großmann, T.: Constrained Peptides with Fine-Tuned Flexibility Inhibit NF-Y Transcription Factor Assembly. Angewandte Chemie, International Edition 58 (48), S. 17351 - 17358 (2019)
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Jeganathan, S.; Wendt, M.; Kiehstaller, S.; Brancaccio, D.; Kuepper, A.; Pospiech, N.; Carotenuto, A.; Novellino, E.; Hennig, S.; Grossmann, T.: Constrained Peptides with Fine-Tuned Flexibility Inhibit NF-Y Transcription Factor Assembly. Angewandte Chemie 131, S. 1 - 9 (2019)
Zeitschriftenartikel
Krüger, D. M.; Neubacher, S.; Großmann, T.: Protein-RNA interactions: structural characteristics and hotspot amino acids. RNA 24 (11), S. 1457 - 1465 (2018)
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Held, A.; Glas, A.; Dietrich, L.; Bollmann, M.; Brandstädter, K.; Grossmann, T.; Lohmann, C.H.; Pap, T.; Bertrand, J.: Targeting b-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage. Osteoarthritis and Cartilage 26 (6), S. 818 - 823 (2018)
Zeitschriftenartikel
Schmidtgall, B.; Kuepper, A.; Meng, M.; Grossmann, T.; Ducho, C.: Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction. Chemistry – A European Journal 24 (7), S. 1544 - 1553 (2018)
Zeitschriftenartikel
McLoughlin, N. M.; Mueller, C.; Grossmann, T.: The Therapeutic Potential of PTEN Modulation: Targeting Strategies from Gene to Protein. Cell Chemical Biology 25 (1), S. 19 - 29 (2018)
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Krüger, D. M.; Glas, A.; Bier, D.; Pospiech, N.; Wallraven, K.; Dietrich, L.; Ottmann , C.; Koch, O.; Hennig, S.; Grossmann, T.: Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein−Protein Interactions. Journal of Medicinal Chemistry 60 (21), S. 8982 - 8988 (2017)
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Waldmann, H.; Valeur, E.; Guéret, S. M.; Adihou, H.; Gopalakrishnan, R.; Lemurell, M.; Grossmann, T.; Plowright, A. T.: New Modalities for Challenging Targets in Drug Discovery. Angewandte Chemie 129 (35), S. 10428 - 10459 (2017)
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Waldmann, H.; Valeur, E.; Guéret, S. M.; Adihou, H.; Gopalakrishnan, R.; Lemurell, M.; Grossmann, T.; Plowright, A. T.: New Modalities for Challenging Targets in Drug Discovery. Angewandte Chemie International Edition 56 (35), S. 10294 - 10323 (2017)
Zeitschriftenartikel
Dietrich, L.; Rathmer, B.; Ewan, K.; Bange, T.; Heinrichs, S.; Dale, T. C.; Schade, D.; Grossmann, T.: Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling that Targets β-Catenin Protein-Protein Interactions. Cell Chemical Biology 24 (8), S. 958 - 968 (2017)
Zeitschriftenartikel
White, M. D.; Klecker, M.; Hopkinson, R. J.; Weits, D. A.; Müller, C.; Naumann, C.; O´Neill, R.; Wickens, J.; Yang, J.; Brooks-Bartlett, J. C. et al.; Garman, E. F.; Grossmann, T.; Dissmeyer, N.; Flashman, E.: Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets. Nature Communications 8, 14690, S. 1 - 9 (2017)
Zeitschriftenartikel
Glas, A.; Wamhoff, E.-C.; Krüger, D. M.; Rademacher, C.; Grossmann, T.: Increased Conformational Flexibility of a Macrocycle–Receptor Complex Contributes to Reduced Dissociation Rates. Chemistry – A European Journal 23 (64), S. 16157 - 16161 (2017)
Zeitschriftenartikel
Stiller, C.; Krüger, D. M.; Brauckhoff, N.; Schmidt, M.; Janning, P.; Salamon, H.; Grossmann, T.: Translocation of an Intracellular Protein via Peptide-Directed Ligation. ACS Chemical Biology, S. 1 - 6 (2016)
Zeitschriftenartikel
Viennet, T.; Viegas, A.; Kuepper, A.; Arens, S.; Gelev, V.; Petrov, O.; Grossmann, T.; Heise, H.; Etzkorn, M.: Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization. Angewandte Chemie International Edition 55 (36), S. 10746 - 10750 (2016)
Zeitschriftenartikel
Viennet, T.; Viegas, A.; Kuepper, A.; Arens, S.; Gelev, V.; Petrov, O.; Grossmann, T.; Heise, H.; Etzkorn, M.: Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization. Angewandte Chemie 128 (36), S. 10904 - 10908 (2016)
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Cromm, P. M.; Spiegel, J.; Küchler, P.; Dietrich, L.; Kriegesmann, J.; Wendt, M.; Goody, R. S.; Waldmann, H.; Grossmann, T.: Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chemical Biology 11 (8), S. 2375 - 2382 (2016)
Zeitschriftenartikel
Cromm, P. M.; Schaubach, S.; Spiegel, J.; Fürstner, A.; Grossmann, T.; Waldmann, H.: Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides. Nature Communications 7, 11300, S. 1 - 7 (2016)
Zeitschriftenartikel
Cromm, P. M.; Wallraven, K.; Glas, A.; Bier, D.; Fürstner, A.; Ottmann, C.; Grossmann, T.: Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis. ChemBioChem: A European Journal of Chemical Biology 17, S. 1 - 6 (2016)
Zeitschriftenartikel
Cromm, P. M.; Spiegel, J.; Grossmann, T.; Waldmann, H.: Direct Modulation of Small GTPase Activity and Function. Angewandte Chemie, International Edition 54 (46), S. 13516 - 13537 (2015)
Zeitschriftenartikel
Cromm, P. M.; Spiegel, J.; Grossmann, T.; Waldmann, H.: Direkte Modulation von Aktivität und Funktion kleiner GTPasen. Angewandte Chemie 127 (46), S. 13718 - 13741 (2015)
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