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Journal Article (2861)

Journal Article
Pkolo, E. A.; Pahl, A.; Sievers, S.; Nelson, A.; Marsden, S.: Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp3-Rich Compounds With Distinct Phenotypic Effects. Chemistry – A European Journal (2023)
Journal Article
Bürgi, J.; Lil, P.; Giannopoulou, E.-A.; Jeffries, C. M.; Chojnowski, G.; Raunser, S.; Gatsogiannis, C.; Wilmanns, M.: Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase. Biological Chemistry Hoppe-Seyler (2023)
Journal Article
Avathan Veettil, A.; Kirchhoff, J.-L.; Brieger, L.; Strohmann, C.; Wu, P.: Petasis Sequence Reactions for the Scaffold-Diverse Synthesis of Bioactive Polycyclic Small Molecules. ACS Omega 8 (1), pp. 1168 - 1181 (2023)
Journal Article
Withmarsh-Everiss, T.; Wang, Z.; Hauberg Hansen, C.; Depta, L.; Sassetti, E.; Dan, O. R.; Pahl, A.; Sievers, S.: Identification of biologically diverse tetrahydronaphtalen-2-ols through the synthesis and phenotypic profiling of chemically diverse, estradiol-inspired compounds. ChemBioChem: A European Journal of Chemical Biology (2023)
Journal Article
Rao, V.U. B.; Wang, C.; Demarque, D. P.; Grassin, C.; Otte, F.; Merten, C.; Strohman, C.; Loh, C. C. J.: A synergistic Rh(I)/organoboron-catalysed site-selective carbohydrate functionalization that involves multiple stereocontrol. Nature Chemistry (2022)
Journal Article
Flegel, J.; Shaaban, S.; Jia, Z.-J.; Schulte, B.; Lian, Y.; Krzyzanowski, A.; Metz, M.; Schneidewind, T.; Wesseler , F.; Flegel, A. et al.; Reich, A.; Brause, A.; Xue, G.; Zhang, M.; Dötsch, L.; Stender, I. D.; Hoffmann, J.-E.; Scheel, R.; Janning, P.; Rastinejad, F.; Schade, D.; Strohmann, C.; Antonchick, A. P.; Sievers, S.; Alves, P.; Ziegler, S.; Waldmann, H.: The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. European Journal of Medicinal Chemistry (2022)
Journal Article
Hui, C.; Antonchick, A. P.: Methodology-driven efficient synthesis of cytotoxic (±)-piperarborenine B. Green Synthesis and Catalysis 3 (4), pp. 339 - 348 (2022)
Journal Article
Krzyzanowski, A.; Esser, L. M.; Willaume, A.; Prudent, R.; `T Hart, P.; Waldmann, H.: Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors. European Journal of Medicinal Chemistry (2022)
Journal Article
Wesseler, F.; Lohmann, S.; Riege, D.; Halver, J.; Roth, A.; Picholo, C.; Weber, S.; Takamiya, M.; Müller, E.; Ketzel, J. et al.; Flegel, J.; Gihring, A.; Rastegar, S.; Bertrand, J.; Baumann, U.; Knippschild, U.; Pfeifer, C.; Sievers, S.; Waldmann, H.; Schade, D.: Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype. Journal of Medicinal Chemistry (2022)
Journal Article
d'Amico, E.; Ud Din Ahmad, M.; Cmentowski, V.; Girbig, M.; Müller, F.; Wohlgemuth, S.; Brockmeyer, A.; Maffini, S.; Vetter, I. R.; Carter, A. P. et al.; Perrakis, A.; Musacchio, A.: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. The Journal of Cell Biology: JCB 221 (2022)
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Picard, L. K.; Littwitz-Salomon, E.; Waldmann, H.; Watzl, C.: Inhibition of Glucose Uptake Blocks Proliferation but Not Cytotoxic Activity of NK Cells. Cells 11 (21) (2022)
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Boltje, D. B.; Hoogenboom, J. P.; Jakobi, A. J.; Jensen, G. J.; Jonker, C. T.H.; Kaag, M. J.; Koster, A. J.; Last, M. G.F.; de Agrela Pinto, C.; Plitzko, J. M. et al.; Raunser, S.; Tacke, S.; Wang, Z.; van der Wee, E. B.; Wepf, R.; den Hoedt, S.: A cryogenic, coincident fluorescence, electron and ion beam microscope. eLife (2022)
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Oosterheert, W.; Klink, B. U.; Belyy, A.; Pospich, S.; Raunser, S.: Structural Basis of actin filament assembly and aging. Nature (2022)
Journal Article
Young, R.; Flitsch, S.; Grigalunas, M.; Leeson, P.; Quinn, R.; Turner, N.; Waldmann, H.: The Time and Place for Nature in Drug Discovery. Journal of the American Chemical Society 2 (11) (2022)
Journal Article
Grethe, C.; Schmidt, M.; Kipka, G.-M.; O'Dea, R.; Gallant, K.; Janning, P.; Gersch, M.: Structural basis for specific inhibition of the deubiquitinase UCHL1. Nature Communications 13 (2022)
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