Publications

Tong , Y.; Lee, Y.; Liu, X.; Childs-Diney, J. L.; Suresh , B. M.; Benhamou, R.; Yang, C.; Li, W.; Costales, M. G.; Haniff, H. S. et al.; Sievers, S.; Abegg, D.; Wegner, T.; Paulisch, T. O.; Lekah, E.; Grefe, M.; Crynen , G.; Van Meter, M.; Wang, T.; Gibaut, Q. M. R.; Cleveland, J. L.; Adibekian, A.; Glorius, F.; Waldmann, H.; Disney, M. D.: Programming inactive RNA-binding small molecules into bioactive degraders. Nature (2023)

Polley, S.; Müschenborn, H.; Terbeck, M.; De Antoni, A.; Vetter, I. R.; Dogterom, M.; Musacchio, A.; Volkov, V. A.; Huis in´t Veld, P. J.: Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding. EMBO Journal (2023)

Rice, G.; Wagner, T.; Stabrin, M.; Sitsel, O.; Prumbaum, D.; Raunser, S.: TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining. Nature Methods (2023)

Hwang, J.; Haacke, N.; Borgelt, L.; Qiu, X.; Gasper, R.; Wu, P.: Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry (2023)

Wang, Z.; Raunser, S.: Structural Biochemistry of Muscle Contraction. Annual Review of Biochemistry (2023)

Joshi, M. S.; Stanoev, A.; Hübinger, J.; Soetje, B.; Zorina, V.; Rossmannek, L.; Michel, K.; Müller, S.; Bastiaens, P. I. H.: The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling. EMBO Journal (2023)

Goebel, L.; Kirschner, T.; Koska, S.; Rai, A.; Janning, P.; Maffini, S.; Vatheuer, H.; Czodrowski, P.; Goody, R. S.; Müller, M. et al.; Rauh, D.: Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife (2023)

Chen, C.; Piano, V.; Alex, A.; Hahn, S. J.; Huis in´t Veld, P. J.; Roy, B.; Fergle, D.; Musacchio, A.; Joglekar, A. P.: The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex. Nature Communications 14 (1) (2023)

Liu, J.; Malick, S.; Grassin, C.; Lucas, B.; Schölermann, B.; Pahl, A.; Scheel, R.; Strohmann Carsten; Protzel, C.; Berg, T. et al.; Merten, C.; Waldmann, H.: Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles. Angewandte Chemie, International Edition in English (2023)

Pal, S.: Impact of Hydrogen-Bond Surrogate Model on Helix Stabilization and Development of Protein-Protein Interaction Inhibitors. ChemistrySelect 8 (2023)

Bieling, P.; Rottner, K.: From WRC to Arp2/3: Collective molecular mechanisms of branched actin network assembly. Current Opinion in Cell Biology (2023)

Pkolo, E. A.; Pahl, A.; Sievers, S.; Nelson, A.; Marsden, S.: Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp3-Rich Compounds With Distinct Phenotypic Effects. Chemistry – A European Journal (2023)

Bürgi, J.; Lil, P.; Giannopoulou, E.-A.; Jeffries, C. M.; Chojnowski, G.; Raunser, S.; Gatsogiannis, C.; Wilmanns, M.: Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase. Biological Chemistry Hoppe-Seyler (2023)

Avathan Veettil, A.; Kirchhoff, J.-L.; Brieger, L.; Strohmann, C.; Wu, P.: Petasis Sequence Reactions for the Scaffold-Diverse Synthesis of Bioactive Polycyclic Small Molecules. ACS Omega 8 (1), pp. 1168 - 1181 (2023)

Withmarsh-Everiss, T.; Wang, Z.; Hauberg Hansen, C.; Depta, L.; Sassetti, E.; Dan, O. R.; Pahl, A.; Sievers, S.: Identification of biologically diverse tetrahydronaphtalen-2-ols through the synthesis and phenotypic profiling of chemically diverse, estradiol-inspired compounds. ChemBioChem: A European Journal of Chemical Biology (2023)