Publications
Journal Article (2950)
Journal Article
An Indole Dearomatization Strategy for the Synthesis of Pseudo-Natural Products. ChemBioChem: A European Journal of Chemical Biology (2025)
Journal Article
The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning. The EMBO Journal (2025)
Journal Article
Interactions with multiple inner kinetochore proteins determine mitotic localization of FACT. Journal of Cell Biology (2025)
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Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment. Chemistry (2025)
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Phenotype-directed discovery of diverse, biologically-relevant molecular scaffolds. Chemical Communications (2025)
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Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST. Journal of Medicinal Chemistry (2025)
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Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM. Proceedings of the National Academy of Sciences of the United States of America (2025)
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Multistate kinetics of the syringe-like injection mechanism of Tc toxins. Science Advances (2025)
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Phenomics-based Discovery of Novel Orthosteric Choline Kinase Inhibitors. Angewandte Chemie, International Edition in English (2024)
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Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53. Nature Chemical Biology (2024)
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Regulation of minimal spindle midzone organization by mitotic kinases. Nature Communications (2024)
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Protocol for validating liquid-liquid phase separation as a driver of membraneless organelle assembly in vitro and in human cells. STAR Protoc. (2024)
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A compound-target pairs dataset: differences between drugs, clinical candidates and other bioactive compounds. Scientific Data (2024)
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LIN28-Targeting Chromenopyrazoles and Tetrahydroquinolines Induced Cellular Morphological Changes and Showed High Biosimilarity with BRD PROTACs. ChemMedChem (2024)
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Long non-coding RNA GRASLND links melanoma differentiation and interferon-gamma response. Frontiers in Molecular Biosciences (2024)