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Journal Article (2841)

Journal Article
d'Amico, E.; Ud Din Ahmad, M.; Cmentowski, V.; Girbig, M.; Müller, F.; Wohlgemuth, S.; Brockmeyer, A.; Maffini, S.; Vetter, I. R.; Carter, A. P. et al.; Perrakis, A.; Musacchio, A.: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. The Journal of Cell Biology: JCB 221 (2022)
Journal Article
Schölermann, B.; Bonowski, J.; Grigalunas, M.; Burhop, A.; Xie, Y.; Hook, J.; Liu, J.; Nelson, A.; Dow, M.; Nowak, C. et al.; Pahl, A.; Sievers, S.; Ziegler, S.: Identification of Dihydroorotate Dehydrogenase Inhibitors using the Cell Painting Assay. ChemBioChem: A European Journal of Chemical Biology (2022)
Journal Article
Grigalunas, M.; Patil, S.; Krzyzanowski, A.; Pahl, A.; Flegel, J.; Schölermann, B.; Xie, J.; Sievers, S.; Ziegler, S.; Waldmann, H.: Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry – A European Journal (2022)
Journal Article
Davies, C.; Dötsch, L.; Ciulla, M. G.; Hennes, E.; Yoshida, K.; Gasper, R.; Scheel, R.; Sievers, S.; Strohmann, C.; Kumar, K. et al.; Ziegler, S.; Waldmann, H.: Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angewandte Chemie, International Edition in English (2022)
Journal Article
Rai, A.; Singh, A. K.; Bleimling, N.; Posern, G.; Vetter, I. R.; Goody, R. S.: Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nature Communications 13 (2022)
Journal Article
Belyy, A.; Lindemann, F.; Roderer, D.; Funk, J.; Bardiaux, B.; Protze, J.; Bieling, P.; Oschkinat, H.; Raunser, S.: Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin. Nature Communications 13 (2022)
Journal Article
Celestino, R.; Gama, J. B.; Castro-Rodrigues, A. F.; Barbosa, D. B.; Rocha, H.; d'Amico, E.; Musacchio, A.; Carvalho, A. X.; Morais-Cabral, J. H.; Gassmann, R.: JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport. The Journal of Cell Biology: JCB (2022)
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Li, T.-D.; Bieling, P.; Weichsel, J.; Mullins, R. D.; Fletcher , D. A.: The molecular mechanism of load adaptation by branched actin networks. eLife (2022)
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Akhilesh, N.; Abishek , D.; Robert , L.; Koseska, A.: Cells use molecular working memory to navigate inchanging chemoattractant fields. eLife (2022)
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Wu, P.; Goebel, G. L.; Qiu, X.: Kinase-targeting small-molecule inhibitors and emerging bifunctional molecules. Trends in Pharmacological Sciences (2022)
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Hui, C.; Liu, Y.; Jiang, M.; Wu, P.: Cyclobutane-containing scaffolds in bioactive small molecules. Trends in Chemistry (2022)
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Pesenti, M.; Raisch, T.; Conti, D.; Walstein, K.; Hoffmann, I.; Vogt, D.; Prumbaum, D.; Vetter, I. R.; Raunser, S.; Musacchio, A.: Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization. Molecular Cell 82, pp. 1 - 19 (2022)
Journal Article
Borshchevskiy, V.; Kovalev, K.; Round, E.; Efremov, R.; Astashkin, R.; Bourenkov, G.; Bratanov, D.; Balandin, T.; Chizhov, I.; Baeken, C. et al.; Gushchin, I.; Kuzmin, A.; Alekseev, A.; Rogachev, A.; Willbold, D.; Engelhard, M.; Bamberg, E.; Büldt, G.; Gordeliy, V.: True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nature Structural and Molecular Biology, pp. 1 - 27 (2022)
Journal Article
Jones, P.; Waldmann, H.: IMI European Lead Factory — democratizing access to highthroughput screening. Nature Reviews Drug Discovery 21, pp. 245 - 246 (2022)
Journal Article
Openy, J.; Amrahova, G.; Chang, J.-Y.; Noisier, A.; `T Hart, P.: Solid-phase peptide modification via deaminative photochemical Csp3- Csp3 bond formation using Katritzky salts. Chemistry – A European Journal, pp. 1 - 9 (2022)
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