Publications

Raveena, R.; Ramadas, B.; Becker, S.: A General Enzymatic Strategy for Site-Specific Incorporation of Modified Genetic Building Blocks Into DNA. Advanced Science (2026)

Klink, N.; Urban, S.; Seier, J. A.; Adhikari, B.; Schwalm, M. P.; Müller, J.; Dorsch, M.; Steinbach, P.; Jung, J.; Vogt, M. et al.; Kaschani, F.; Koch, J.; Führer, S.; Kaiser, M.; Schulze, N.; Knapp, S.; Wolf, E.; Paschen, A.; Grüner, B. M.; Gersch, M.: Targeted degradation of USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors. Nature Communications (2026)

Jiang, M.; Hösle, D.; Liu, Y.; Sievers, S.; Wu, P.: NRAS mRNA-Degrading Bifunctional Small Molecules Induce Diverse Cellular Morphological Changes in Cancer CellsClick to copy article link. JACS Au (2026)

Ren, L.; Esposito-Verza, A.; Gasper, R.; Pesenti, M.; Janning, P.; Müller, F.; Koerner, C.; Geue, P.; Wohlgemuth, S.; Vetter, I. R. et al.; Musacchio, A.: Molecular anatomy of PLK1 master docking motifs. Nature Communications (2026)

Engelhard, L.; Schiller, D.; Zambrano-Mila, M.; Keliuotyte, K.; Buchmüller, B.; Tiwari, S.; Imig, J.; Simeone, A.; Schröter, C.; Becker, S. et al.; Summerer, D.: HM-DyadCap - capture and mapping of 5-hydroxymethylcytosine/5-methylcytosine CpG dyads in mammalian DNA. Nucleic Acids Research (2026)

Huebinger, J.; Bastiaens, P. I. H.: Determination of factors that allow cryogenic nanoscopy with high power illumination without devitrification. PLOS ONE (2026)

Gsell, C.; Rebmann, P.; Opara, K.; Beuck, C.; Bayer, P.; Bier, D.; Vetter, I. R.; Schrader, T.: Molecular tweezer-peptide conjugates disrupt the protein-protein interaction between survivin and histone H3 essential in mitosis. Beilstein Journal of Organic Chemistry (2026)

Engelhard, L.; Cakil, Z. V.; Zambrano-Mila, M. S.; Eppmann, S.; Gonzalez, T.; Janning, P.; Becker, S.; Summerer, D.: Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand-Symmetric and -Asymmetric 5-Hydroxymethylcytosine-Modifications in DNA. Advanced Science (2026)

Haase, M. A.; Lazar-Stefanita, L.; Baudry, L.; Wudzinska, A.; Zhou, X.; Rokas, A.; Hittinger, C. T.; Pfander, B.; Musacchio, A.; Boeke, J. D.: Ancient co-option of LTR retrotransposons as yeast centromeres. Nature (2026)

Greiner, L.; Bernal, F. A.; Thavam, S.; Brachthäuser, M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Design, Synthesis, and Biological Evaluation of Pseudo-Natural Products Inspired by Aryloctahydroindole Alkaloids. ChemMedChem (2026)

Walstein, K.; Hill, L.; Vogt, D.; Oberste-Lehn, L.; Janning, P.; Vetter, I. R.; Pan, D.; Musacchio, A.: M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans. The EMBO Journal (2026)

Zhang, R.; Liu, J.; Gasper, R.; Unger, A.; Kaschani, F.; Kaiser, M.; Janning, P.; Waldmann, H.: Covalent modification of a glutamic acid inspired by HaloTag technology. Nat Commun (2026)

Esposito-Verza, A.; Conti, D.; Pedroso, P. D. R.; Oberste-Lehn, L.; Körner, C.; Wohlgemuth, S.; Mansurkhodzhaev, A.; Vetter, I. R.; Pesenti, M.; Musacchio, A.: Molecular requirements for PLK1 activation by T-loop phosphorylation. The EMBO Journal (2026)

Müller, M.; Niemeyer, K.; Ojha, N. K.; Porav, S. A.; Vinayagam, D.; Urban, N.; Büchau, F.; Oleinikov, K.; Makke, M.; Bauer, C. C. et al.; Johnson, A. V.; Muench, S.; Zufall, F.; Bruns, D.; Schwarz, Y.; Raunser, S.; Leinders-Zufall, T.; Bon, R. S.; Schaefer, M.; Thorn-Seshold, O.: Ideal efficacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissues. Nature Chemical Biology (2026)

Hennes, E.; Lucas, B.; Scholes, N. S.; Cheng, X.-F.; Scott, D. C.; Bischoff, M.; Reich, K.; Gasper, R.; Lucas, M.; Xu, T. T. et al.; Rossini, S.; Pulvermacher, L.-M.; Dötsch, L.; Imrichova, H.; Brause, A.; Führer, S.; Naredla, K. R.; Sievers, S.; Kumar, K.; Janning, P.; Orabona, C.; Gersch, M.; Murray, P. J.; Schulmann, B. A.; Winter, G. E.; Ziegler, S.; Waldmann, H.: Monovalent pseudo-natural products supercharge degradation of IDO1 by its native E3 KLHDC3. Nature Chemistry (2026)