Journal Article (2903)
Journal Article
Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases. Journal of the American Chemical Society (2023)
Journal Article
Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity. Journal of Medicinal Chemistry (2023)
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12 (8) (2023)
Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells. Biology Open
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Macrocyclic peptides as inhibitors of WDR5 - lncRNA interactions. Chemical Communications (2023)
Journal Article
14 (2023)
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway. Chemical Science
Journal Article
Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36. Nature Chemical Biology (2023)
Journal Article
14 (31) (2023)
Rationally designed stapled peptides allosterically inhibit PTBP1 RNA-binding. Chemical Science
Journal Article
18 (10), pp. 2101 - 2113 (2023)
Targeting Ribonucleases with Small Molecules and Bifunctional Molecules. ACS Chemical Biology
Journal Article
Cooperative Lewis Acid-1,2,3-Triazolium-Aryloxide Catalysis: Pyrazolone Addition to Nitroolefins as Entry to Diaminoamides. Angewandte Chemie, International Edition in English (2023)
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Morphological subprofile analysis for bioactivity annotation of small molecules. Cell Chemical Biology (2023)
Journal Article
83 (11), pp. 1856 - 1871 (2023)
Structural basis of mRNA binding by the human FERRY Rab5 effector complex. Molecular Cell
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Chromenopyrazole−Peptide Conjugates as Small-Molecule Based Inhibitors Disrupting the Protein−RNA Interaction of LIN28-let-7. ChemBioChem: A European Journal of Chemical Biology (2023)
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Programming inactive RNA-binding small molecules into bioactive degraders. Nature (2023)
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Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding. EMBO Journal (2023)
Journal Article
TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining. Nature Methods (2023)