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How pruning the cytoskeleton moves the cell

September 20, 2021

Cells are characterized to be stable yet highly flexible. They constantly modify their shape and even move through tissue. These vital properties are based on a dynamically organized network of branched actin filaments, which generates pushing forces ...

Characterized drugs show unexpected effects

July 22, 2021

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes. However, there is no perfect drug that affects the one target in the body: no effect without side effects, as also described in ...

Manufacturing the core engine of cell division

June 30, 2021

It´s a cellular process going on since one billion years, yet we are not able to replicate it, nor to fully understand it. Mitosis, the mechanism of cell division that is so important for life, involves more that 100 proteins at its core. Now, the ...

What Termites and Cells Have in Common

June 24, 2021

Nature is full of fascinating patterns. Plants show beautiful spiral growth, regularly arranged leaves and petals, animals impress us with their striped and dotted furs and social insects build complex nest structures. These almost perfectly arranged ...

Zooming in on Muscle Cells

March 24, 2021

Scientists have produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, by using electron cryo-tomography (cryo-ET). The international team, led by Stefan Raunser, Director at the ...

Stimulating the Immune System to Fight Cancer

March 17, 2021

Cancer cells have evolved mechanisms to escape the body's immune defense. Agents that prevent immune escape are attractive targets for the development of new cancer therapies. A group of scientists led by Prof. Dr. Dr. h.c. Herbert Waldmann and Dr ...

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