We are interested in mechanisms, how the dynamic shape of cells emerges from interactions between cytoskeletal structures and their regulators.

Leif Dehmelt

We are interested in mechanisms, how the dynamic shape of cells emerges from interactions between cytoskeletal structures and their regulators.
We use cryo-electron microscopy to study the structure and function of membrane proteins and macromolecular complexes.

Stefan Raunser

We use cryo-electron microscopy to study the
structure and function of membrane proteins
and macromolecular complexes.
How do cells process extracellular information and thereby determine their identity?

Philippe Bastiaens

How do cells process extracellular information and thereby determine their identity?
We focus on the development of innovative methodologies for the synthesis of interesting compounds to study biological systems.

Andrey Antonchick

We focus on the development of innovative methodologies for the synthesis of interesting compounds to study biological systems.
We study the molecular mecahnisms that regulate changes in cell morphology.

Peter Bieling

We study the molecular mecahnisms that regulate changes in cell morphology.
How do cells control dynamic microtubule instability to ensure genome stability?

Alex Bird

How do cells control dynamic microtubule instability to ensure genome stability?
How do cells fuse together?

Matias Hernandez

How do cells fuse together?
Roles and mechanisms of Ras-family GTPase, in particular Rab GTPase, in the regullation of intracellular vesicukar transport

Roger Goody

Roles and mechanisms of Ras-family GTPase, in particular Rab GTPase, in the regullation of intracellular vesicukar transport
How does intercellular communication establish information processing in cells to  dynamically maintain their identity?

Aneta Koseska

How does intercellular communication establish information processing in cells to  dynamically maintain their identity?
How do cellular functions work together to faithfully segregate the genome?

Stefano Maffini

How do cellular functions work together to faithfully segregate the genome?
We want to understand the dynamic interaction between pore forming proteins and lipid membranes.

Christos Gatsogiannis

We want to understand the dynamic interaction between pore forming proteins and lipid membranes.
Mass spectrometry analysis of organic compounds, proteins and proteom.

Petra Janning

Mass spectrometry analysis of organic compounds, proteins and proteom.
Finding the needle in the haystack: Exploring the mechanism of action of bioactive small molecules.

Slava Ziegler

Finding the needle in the haystack: Exploring the mechanism of action of bioactive small molecules.
We investigate the molecular basis of cell division in eukaryotes.

Andrea Musacchio

We investigate the molecular basis of cell division in eukaryotes.
We develop novel synthesis to produce natural product-inspired compound collections and use them for the study of biological phenomena.

Herbert Waldmann

We develop novel synthesis to produce natural product-inspired compound collections and use them for the study of biological phenomena.
How do cells turn signal into fate?

Christian Schröter

How do cells turn signal into fate?
How do cells maintain genomic stability during meiosis?

Gerben Vader

How do cells maintain genomic stability during meiosis?
We investigate the molecular mechanisms controlling chromatin dynamics in vivo.

Heinz Neumann

We investigate the molecular mechanisms controlling chromatin dynamics in vivo.

Our Research Groups

The Institute consists of four departments. Each of them is headed by a director and is scientifically autonomous. In each of the four departments, thematically related research groups are integrated. They have their own scientific priorities and pursue independent research projects.

In our projects, we not only think in departments or disciplines. We focus on communication and cooperation. We draw inspiration from each other’s different perspectives, develop joint projects and thus benefit from the expertise of the other subject areas.

Mechanistic Cell Biology: Musacchio I Bird I Vader I Systemic Cell Biology: Bastiaens I Bieling I Dehmelt I Koseska I Schröter I Structural Biochemistry: Raunser I Hernandez I Neumann I Chemical Biology: Waldmann I Antonchick I Loh I  Physical Biochemistry (Emeritus): Goody

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