Cells buzz with millions of different biomolecules that diffuse chaotically through their substructures, yet they manage to ensure exquisite functional and spatial specificity. Distinct biomolecules interact specifically in cellular processes and ...

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin family are pivotal partners in this process ...

Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein ...

Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal ‘Makes caterpillars floppy 1’ (Mcf1) toxin, leading them to first become droopy and then ...

You suddenly feel sick - pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host’s defense mechanisms and vital cell functions. Before these deadly toxins ...

Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical ...