Publications

Gasper, R.; Wittinghofer, A.: The Ras switch in structural and historical perspective. Biological Chemistry 401 (1), pp. 143 - 163 (2019)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEδ targeting PROTAC that impairs lipid metabolism. Angewandte Chemie, International Edition 59 (14), pp. 5595 - 5601 (2019)

Merino, F.; Pospich, S.; Raunser, S.: Towards a structural understanding of the remodeling of the actin cytoskeleton. Seminars in Cell & Developmental Biology 102 (SI), pp. 51 - 64 (2019)

Huis in´t Veld, P. J.; Volkov, V. A.; Stender, I. D.; Musacchio, A.; Dogterom, M.: Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling. eLife 8:e49539, e49539, pp. 1 - 29 (2019)

Barbosa, J.; Martins, T.; Bange, T.; Tao, L.; Conde, C.; Sunkel, C.: Polo regulates Spindly to prevent premature stabilization of kinetochore-microtubule attachments. The EMBO Journal 39 (2), e100789, pp. 1 - 22 (2019)

Lunk, I.; Litty, F.-A.; Hennig, S.; Vetter, I. R.; Kotthaus, J.; Altmann, K. S.; Ott, G.; Havemeyer, A.; García , C. C.; Clement, B. et al.; Schade, D.: Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). Journal of Medicinal Chemistry 63 (1), pp. 425 - 432 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), pp. 5721 - 5729 (2019)

Reckzeh, E. S.; Waldmann, H.: Small Molecule Inhibition of Glucose Transporters GLUT 1‐4. ChemBioChem: A European Journal of Chemical Biology 20, pp. 1 - 22 (2019)

Roderer, D.; Schubert, E.; Sitsel, O.; Raunser, S.: Towards the application of Tc toxins as a universal protein translocation system. Nature Communications 10 (1), pp. 1 - 11 (2019)

Pobbati, A. V.; Mejuch, T.; Chakraborty, S.; Karatas, H.; Bharath, S. R.; Guéret, S. M.; Goy, P.-A.; Hahne, G.; Pahl, A.; Sievers, S. et al.; Guccione, E.; Song, H.; Waldmann, H.; Hong, W.: Identification of Quinolinols as Activators of TEAD-dependent Transcription. ACS Chemical Biology, pp. 1 - 35 (2019)

Cromm, P. M.; Adihou, H.; Kapoor, S.; Vazquez-Chantada, M.; Davey, P.; Longmire, D.; Hennes, E.; Hofer, W.; Küchler, P.; Chiarparin, E. et al.; Waldmann, H.; Grossmann, T. N.: Lipidated stapled peptides targeting the acyl binding protein UNC119. ChemBioChem: A European Journal of Chemical Biology, pp. 1 - 10 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), pp. 5770 - 5778 (2019)

Zimmermann, S.; Akbarzadeh, M.; Otte, F.; Strohmann, C.; Sankar, M. G.; Ziegler, S.; Pahl, A.; Sievers, S.; Kumar, K.: A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides. Chemistry – A European Journal 25, pp. 1 - 7 (2019)

Roderer, D.; Hofnagel, O.; Benz, R.; Raunser, S.: Structure of a Tc holotoxin pore provides insights into the translocation mechanism. Proceedings of the National Academy of Sciences of the United States of America, pp. 1 - 8 (2019)

Funk, J.; Merino, F.; Venkova, L.; Heydenreich, L.; Kierfeld, J.; Vargas, P.; Raunser, S.; Piel, M.; Bieling, P.: Profilin and formin constitute a pacemaker system for robust actin filament growth. eLife (e50963), e50963, pp. 1 - 74 (2019)