Publications of Sabrina Pospich

Manik, M.; Pan, M.; Xiao, L.; Gu, W.; Kim, H.; Pospich, S.; Hedger, A.; Vajjhala, P.; Lee, M.; Qian, X. et al.; Landsberg, M.; Ve, T.; Nanson, J.; Raunser, S.; Stacey, K.; Wu, H.; Kobe, B.: Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM. Proceedings of the National Academy of Sciences of the United States of America (2025)

Oosterheert, W.; Klink, B. U.; Belyy, A.; Pospich, S.; Raunser, S.: Structural Basis of actin filament assembly and aging. Nature (2022)

Wang, Z.; Grange, M.; Pospich, S.; Wagner, T.; Kho, A. L.; Gautel, M.; Raunser, S.: Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science 375 (6582), eabn1934, pp. 1 - 13 (2022)

Pospich, S.; Sweeney, H. L.; Houdusse, A.; Raunser, S.: High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. eLife 10, e73724, pp. 1 - 81 (2021)

Klika Škopić, M.; Gramse, C.; Oliva, R.; Pospich, S.; Neukirch, L.; Manisegaran, M.; Raunser, S.; Winter, R.; Weberskirch , R.; Brunschweiger, A.: Towards DNA-encoded Micellar Chemistry: DNA-micelle Association and Environment-sensitivity of Catalysis. Chemistry – A European Journal 27 (39), pp. 10048 - 10057 (2021)

Pospich, S.; Küllmer, F.; Nasufovic, V.; Funk, J.; Belyy, A.; Bieling, P.; Arndt, H.-D.; Raunser, S.: Cryo-EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states. Angewandte Chemie International Edition, pp. 1 - 7 (2021)

Pospich, S.; Küllmer, F.; Nasufovic, V.; Funk, J.; Belyy, A.; Bieling, P.; Arndt , H.-D.; Raunser, S.: Cryo‐EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states. Angewandte Chemie, pp. 1 - 7 (2021)

Stabrin, M.; Schönfeld, F.; Wagner, T.; Pospich, S.; Gatsogiannis, C.; Raunser, S.: TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM. Nature Communications 11, 5716, pp. 1 - 14 (2020)

Wagner, T.; Lusnig, L.; Pospich, S.; Stabrin, M.; Schönfeld, F.; Raunser, S.: Two particle-picking procedures for filamentous proteins: SPHIRE-crYOLO filament mode and SPHIRE-STRIPER. Acta Crystallographica Section D: Structural Biology 76 (Pt.7), pp. 613 - 620 (2020)

Pospich, S.; Merino, F.; Raunser, S.: Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure 28 (4), pp. 437 - 449 (2020)

Merino, F.; Pospich, S.; Raunser, S.: Towards a structural understanding of the remodeling of the actin cytoskeleton. Seminars in Cell & Developmental Biology 102 (SI), pp. 51 - 64 (2019)

Škopić, M. K.; Götte, K.; Gramse, C.; Dieter, M.; Pospich, S.; Raunser, S.; Weberskirch, R.; Brunschweiger, A.: Micellar Brønsted Acid Mediated Synthesis of DNA-Tagged Heterocycles. Journal of the American Chemical Society 141 (26), pp. 10546 - 10555 (2019)

Pospich, S.; Raunser, S.: Single particle cryo-EM-an optimal tool to study cytoskeletal proteins. Current Opinion in Structural Biology 52, pp. 16 - 24 (2018)

Merino, F.; Pospich, S.; Funk, J.; Wagner, T.; Küllmer, F.; Arndt, H.-D.; Bieling, P.; Raunser, S.: Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nature Structural Molecular Biology 25 (6), pp. 528 - 537 (2018)

Pospich, S.; Raunser, S.: The molecular basis of Alzheimer’s plaques. Science 358 (6359), pp. 45 - 46 (2017)

Pospich, S.; Kumpula, E.-P.; von der Ecken, J.; Vahokoski, J.; Kursula, I.; Raunser, S.: Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proceedings of the National Academy of Sciences of the United States of America 114 (40), pp. 10636 - 10641 (2017)