Publications of Herbert Waldmann

Hoock, J. G.; Burhop, A.; Greiner, L. C.; Schölermann, B.; Da Cruz Lopes Guita, C.; Liu, J.; Bag, S.; Pahl, A.; Sievers, S.; Scheel, R. et al.; Strohmann, C.; Ziegler, S.; Grigalunas, M.; Waldmann, H.: An Indole Dearomatization Strategy for the Synthesis of Pseudo-Natural Products. ChemBioChem: A European Journal of Chemical Biology (2025)

Binici, A.; Hennes, E.; Koska, S.; Niemann, J. A.; Reich, A.; Pfaff, C.; Sievers, S.; Kahtn, A. S.; Thomas, D.; Ziegler, S. et al.; Watzl, C.; Waldmann, H.: Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment. Chemistry (2025)

Bauer, L. G.; Ward, J. A.; Díaz-Sáez , L.; Sundström, Y.; Tolvanen, T.; Alarcón Barrera, J. C.; Kostidis, S.; Rogers, C. M.; Panagakou, I.; Singh, U. et al.; Rothweiler, E. M.; Gonzalez Orta, A.; Kaniskan, H. Ü.; Hu, J.; Sievers, S.; Waldmann, H.; Giera, M.; Sundström, M.; Berg, L.; Huber, K.: Phenomics-based Discovery of Novel Orthosteric Choline Kinase Inhibitors. Angewandte Chemie, International Edition in English (2024)

Heinzke, A. L.; Zdrazil, B.; Leeson, P. D.; Young, R. J.; Pahl, A.; Waldmann, H.; Leach, A. R.: A compound-target pairs dataset: differences between drugs, clinical candidates and other bioactive compounds. Scientific Data (2024)

Cheng, X.-F.; Grigalunas, M.; Waldmann, H.: Progress and opportunities of pseudo-natural-product design in molecular discovery. ARKIVOC (2024)

Rezaei Adariani, S.; Agne, D.; Koska, S.; Burhop, A.; Seitz, C.; Warmers, J.; Janning, P.; Metz, M.; Pahl, A.; Sievers, S. et al.; Waldmann, H.; Ziegler, S.: Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of Medicinal Chemistry (2024)

Heinzke, A. L.; Pahl, A.; Zdrazil, B.; Leach, A. R.; Waldmann, H.; Young, R. J.; Leeson, P. D.: Occurrence of "Natural Selection" in Successful Small Molecule Drug Discovery. Journal of Medicinal Chemistry 67 (13), pp. 11226 - 11241 (2024)

Pahl, A.; Grygorenko, O. O.; Konratov, I. O.; Waldmann, H.: Identification of readily available pseudo-natural products. RSC Medicinal Chemistry (2024)

Cigler, M.; Imrichova, H.; Frommelt, F.; Caramelle, L.; Depta, L.; Rukavina, A.; Kagiou, C.; Hannich, T.; Mayor-Ruiz, C.; Superti-Furga, G. et al.; Sievers, S.; Forrester, A.; Laraia, L.; Waldmann, H.; Winter, G.: Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP. Nature Chemical Biology (2024)

Patil, S.; Cremosnik, G. S.; Dötsch, L.; Flegel, J.; Schulte, B.; Maier, K. C.; Zumer, K.; Cramer, P.; Janning, P.; Sievers, S. et al.; Waldmann, H.: Tafbromin selectively targets the TAF1 bromodomain. Angewandte Chemie, International Edition in English (2024)

Tandon, A.; Santura, A.; Waldmann, H.; Pahl, A.; Czodrowski, P.: Identification of lysosomotropism using explainable machine learning and morphological profiling cell painting data. RSC Medicinal Chemistry (2024)

Pahl, A.; Liu, J.; Patil, S.; Rezaei Adariani, S.; Schölermann, B.; Warmers, J.; Bonowski, J.; Koska, S.; Akbulut, Y.; Seitz, C. et al.; Sievers, S.; Ziegler, S.; Waldmann, H.: Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of Medicinal Chemistry (2024)

Knyazeva, A.; Li, S.; Corkery, D. P.; Shankar, K.; Herzog, L. K.; Zhang, X.; Singh, B.; Niggemeyer, G.; Grill, D.; Gilthorpe, J. D. et al.; Gaetani, M.; Carlson, L.-A.; Waldmann, H.; Wu, Y.-W.: A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation. PNAS (2024)

Wang, L.; Yilmaz, F.; Yildirim, O.; Schölermann, B.; Bag, S.; Greiner, L.; Pahl, A.; Sievers, S.; Scheel, R.; Strohmann, C. et al.; Squire, C.; Foley, D. J.; Ziegler, S.; Grigalunas, M.; Waldmann, H.: Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling. Advanced Science (2024)

Picard, L. K.; Niemann, J. A.; Littwitz-Salomon, E.; Waldmann, H.; Watzl, C.: Restriction of Glycolysis Increases Serial Killing Capacity of Natural Killer Cells. International Journal of Molecular Sciences (2024)

Dötsch, L.; Davies, C.; Hennes, E.; Schönfeld, J.; Kumar, A.; Da Cruz Lopes Guita, C.; Ehrler, J. H.; Hiesinger, K.; Thavam, S.; Janning, P. et al.; Sievers, S.; Knapp, S.; Proschak, E.; Ziegler, S.; Waldmann, H.: Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of Medicinal Chemistry (2024)

Bag, S.; Liu, J.; Patil, S.; Bonowski, J.; Schölermann, B.; Zhang, R.; Wang , L.; Pahl, A.; Sievers, S.; Brieger, L. et al.; Strohmann, C.; Grigalunas, M.; Waldmann, H.: A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature Chemistry (2024)

Xue, G.; Xie, J.; Hinterndorfer, M.; Cigler, M.; Dötsch, L.; Imrichova, H.; Lampe, P.; Cheng, X.; Rezaei Adariani, S.; Winter, G. E. et al.; Waldmann, H.: Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype. Nature Communications (2023)

Corkery, D.; Ursu, A.; Lucas, B.; Grigalunas, M.; Kriegler, S.; Oliva, R.; Dec, R.; Koska, S.; Pahl, A.; Sievers, S. et al.; Ziegler, S.; Winter, R.; Wu, Y.; Waldmann, H.: Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair. ChemBioChem: A European Journal of Chemical Biology (2023)

Xie, J.; Pahl, A.; Krzyzanowski, A.; Krupp, A.; Liu, J.; Koska, S.; Schölermann, B.; Zhang, R.; Bonowski, J.; Sievers, S. et al.; Strohmann, C.; Ziegler, S.; Grigalunas, M.; Waldmann, H.: Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space. Angewandte Chemie, International Edition in English (2023)