MPI für molekulare Physiologie Forschung Key Publications keypublications2024 Key Publications 2024 Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53 Gersch Group. Nature Chemical Biology (2024) [mehr] Regulation of minimal spindle midzone organization by mitotic kinases Musacchio Group. Nat Commun (2024) [mehr] Stapled Peptides as Inhibitors of mRNA Deadenylation ‘t Hart Group. Angew Chem Int Ed Engl. (2024) [mehr] Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Bieleing & Raunser Group. Nat Commun (2024) [mehr] Role of protein kinase PLK1 in the epigenetic maintenance of centromeres Musacchio Group. Science (2024) [mehr] Stereoselective Entry into α,α’-C-Oxepane Scaffolds through a Chalcogen Bonding Catalyzed Strain-Release C-Septanosylation Strategy Loh Group. Angew Chem Int Ed Engl. (2024) [mehr] Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP Waldmann Group Nat Chem Biol. (2024) [mehr] Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation Schröter Group. Nat Commun (2024) [mehr] Transient Structural Properties of the Rho GDP-Dissociation Inhibitor Bieling Group. Angew Chem Int Ed Engl. (2024) [mehr] Molecular mechanism of actin filament elongation by formins Bieleing & Raunser Group. Science. (2024) [mehr] Asymmetric Pd/Organoboron-Catalyzed Site-Selective Carbohydrate Functionalization with Alkoxyallenes Involving Noncovalent Stereocontrol Loh Group. Angew Chem Int Ed Engl. (2024) [mehr] Tafbromin selectively targets the TAF1 bromodomain Waldmann Group. Angew Chem Int Ed Engl. (2024) [mehr] A validation strategy to assess the role of phase separation as a determinant of macromolecular localization Musacchio Group. Mol Cell (2024) [mehr] N-Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1 Gersch Group. Angew Chem Int Ed Engl. (2024) [mehr] Harnessing Multistep Chalcogen Bonding Activation in the α-Stereoselective Synthesis of Iminoglycosides Loh Group. J Am Chem Soc. (2024) [mehr]