MPI of Molecular Physiology Research Key Publications keypublications2024 Key Publications 2024 Role of protein kinase PLK1 in the epigenetic maintenance of centromeres Musacchio Group. Science (2024) [more] Stapled Peptides as Inhibitors of mRNA Deadenylation ‘t Hart Group. Angew Chem Int Ed Engl. (2024) [more] Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Bieleing & Raunser Group. Nat Commun (2024) [more] Stereoselective Entry into α,α’-C-Oxepane Scaffolds through a Chalcogen Bonding Catalyzed Strain-Release C-Septanosylation Strategy Loh Group. Angew Chem Int Ed Engl. (2024) [more] Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP Waldmann Group Nat Chem Biol. (2024) [more] Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation Schröter Group. Nat Commun. (2024) [more] Transient Structural Properties of the Rho GDP-Dissociation Inhibitor Bieling Group. Angew Chem Int Ed Engl. (2024) [more] Molecular mechanism of actin filament elongation by formins Bieleing & Raunser Group. Science. (2024) [more] Asymmetric Pd/Organoboron-Catalyzed Site-Selective Carbohydrate Functionalization with Alkoxyallenes Involving Noncovalent Stereocontrol Loh Group. Angew Chem Int Ed Engl. (2024) [more] Harnessing Multistep Chalcogen Bonding Activation in the α-Stereoselective Synthesis of Iminoglycosides Loh Group. J Am Chem Soc. (2024) [more] Structure of the human KMN complex and implications for regulation of its assembly Musacchio & Raunser Group. Nat Struct Mol Biol. (2024). [more] Tafbromin selectively targets the TAF1 bromodomain Waldmann Group. Angew Chem Int Ed Engl. (2024) [more] A validation strategy to assess the role of phase separation as a determinant of macromolecular localization Musacchio Group. Mol Cell (2024) [more] A divergent intermediate strategy yields biologically diverse pseudo-natural products Waldmann Group. Nature Chemistry (2024) [more] N-Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1 Gersch Group. Angew Chem Int Ed Engl. (2024) [more]
