Publikationen von Eyad K. Fansa

Zeitschriftenartikel (18)

Zeitschriftenartikel
Garivet, G.; Hofer, W.; Konitsiotis, A.; Klein, C.; Kaiser, N.; Mejuch, T.; Fansa, E. K.; Alsaabi, R.; Wittinghofer, A.; Bastiaens, P. I. H. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells. Cell Chemical Biology 26 (6), S. 842 - 851 (2019)
Zeitschriftenartikel
Kösling, S. K.; Fansa, E. K.; Maffini, S.; Wittinghofer, A.: Mechanism and dynamics of INPP5E transport into and inside the ciliary compartment. Biological Chemistry 399 (3), S. 277 - 292 (2017)
Zeitschriftenartikel
Martín-Gago, P.; Fansa, E. K.; Winzker, M.; Murarka, S.; Janning, P.; Schultz-Fademrecht, C.; Baumann, M.; Wittinghofer, A.; Waldmann, H.: Covalent Protein Labeling at Glutamic Acids. Cell chemical biology 24 (5), S. 589 - 597 (2017)
Zeitschriftenartikel
Mejuch, T.; Garivet, G.; Hofer, W.; Kaiser, N.; Fansa, E. K.; Ehrt, C.; Koch, O.; Baumann , M.; Ziegler, S.; Wittinghofer, A. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC119–Cargo Interaction. Angewandte Chemie International Edition 56, S. 1 - 7 (2017)
Zeitschriftenartikel
Mejuch, T.; Garivet, G.; Hofer, W.; Kaiser, N.; Fansa, E. K.; Ehrt, C.; Koch, O.; Baumann, M.; Ziegler, S.; Wittinghofer, A. et al.; Waldmann, H.: Small-Molecule Inhibition of the UNC119–Cargo Interaction. Angewandte Chemie 129, S. 1 - 7 (2017)
Zeitschriftenartikel
Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie International Edition 56 (9), S. 2423 - 2428 (2017)
Zeitschriftenartikel
Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6d-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie 129 (9), S. 2463 - 2468 (2017)
Zeitschriftenartikel
Martín-Gago, P.; Fansa, E. K.; Wittinghofer, A.; Waldmann, H.: Structure-based development of PDEδ inhibitors. Biological Chemistry 398 (5-6), S. 535 - 545 (2016)
Zeitschriftenartikel
Nouri, K.; Fansa, E. K.; Amin, E.; Dvorsky, R.; Gremer, L.; Willbold, D.; Schmitt, L.; Timson, D. J.; Ahmadian, M. R.: IQGAP1 Interaction with RHO Family Proteins Revisited KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES. The Journal of Biological Chemistry 291 (51), S. 26364 - 26376 (2016)
Zeitschriftenartikel
Jaiswal, M.; Fansa, E. K.; Kösling, S. K.; Mejuch, T.; Waldmann, H.; Wittinghofer, A.: Novel biochemical and structural insights into the interaction of myristoylated cargo with Unc119 and their release by Arl2/3. The Journal of Biological Chemistry 291 (39), S. 20766 - 20778 (2016)
Zeitschriftenartikel
Papke, B.; Murarka, S.; Vogel, H. A.; Martín-Gago, P.; Kovacevic, M.; Truxius, D.; Fansa, E. K.; Ismail, S.; Zimmermann, G.; Heinelt, K. et al.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.; Bastiaens, P. I. H.: Identification of pyrazolopyridazinones as PDEδ inhibitors. Nature Communications 7, 11360, S. 1 - 9 (2016)
Zeitschriftenartikel
Blaževitš, O.; Mideksa, Y. G.; Šolman, M.; Ligabue, A.; Ariotti, N.; Nakhaeizadeh, H.; Fansa, E. K.; Papageorgiou, A. C.; Wittinghofer, A.; Ahmadian, M. R. et al.; Abankwa, D.: Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering. Scientific Reports 6, 24165, S. 1 - 16 (2016)
Zeitschriftenartikel
Fansa, E. K.; Kösling, S. K.; Zent, E.; Wittinghofer, A.; Ismail, S.: PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity. Nature Communications 7, 11366, S. 1 - 9 (2016)
Zeitschriftenartikel
Fansa, E. K.; Wittinghofer, A.: Sorting of lipidated cargo by the Arl2/Arl3 system. Small GTPases 7 (4), S. 222 - 230 (2016)
Zeitschriftenartikel
Murarka, S.; Martín-Gago, P.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Fansa, E. K.; Ismail, S.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.: Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site. Chemistry – A European Journal 23 (25), S. 6083 - 6093 (2016)
Zeitschriftenartikel
Fansa, E. K.; O’Reilly, N. J.; Ismail, S.; Wittinghofer, A.: The N- and C-terminal ends of RPGR can bind to PDE6δ. EMBO Reports 16 (12), S. 1583 - 1585 (2015)
Zeitschriftenartikel
Kapoor, S.; Fansa, E. K.; Möbitz, S.; Ismail, S.; Winter, R.; Wittinghofer, A.; Weise, K.: Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3. Biophysical Journal 109 (8), S. 1619 - 1629 (2015)
Zeitschriftenartikel
Bravo-Rodriguez, K.; Ismail-Ali, A. F.; Klopries, S.; Kushnir, S.; Ismail, S.; Fansa, E. K.; Wittinghofer, A.; Schulz, F.; Sanchez-Garcia, E.: Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives. ChemBioChem: A European Journal of Chemical Biology 15 (13), S. 1991 - 1997 (2014)
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