Publikationen von Felipe Merino

Gomez, S. M.; Visco, I.; Merino, F.; Bieling, P.; Linser, R.: Transient Structural Properties of the Rho GDP-Dissociation Inhibitor. Angewandte Chemie, International Edition in English (2024)

Raisch, T.; Ciossani, G.; d'Amico, E.; Cmentowski, V.; Carmignani, S.; Maffini, S.; Merino, F.; Wohlgemuth, S.; Vetter, I. R.; Raunser, S. et al.; Musacchio, A.: Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. The EMBO Journal, e110411, S. 1 - 22 (2022)

Belyy, A.; Merino, F.; Mechold, U.; Raunser, S.: Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nature Communications 12 (1), 6628, S. 1 - 9 (2021)

Funk, J.; Merino, F.; Schaks, M.; Rottner, K.; Raunser, S.; Bieling, P.: A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. Nature Communications 12 (1), 5329, S. 1 - 17 (2021)

Vinayagam, D.; Quentin, D.; Yu-Strzelczyk, J.; Sitsel, O.; Merino, F.; Stabrin, M.; Hofnagel, O.; Yu, M.; Ledeboer, M. W.; Nagel, G. et al.; Malojcic, G.; Raunser, S.: Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. eLife 9, e60603, S. 1 - 58 (2020)

Belyy, A.; Merino, F.; Sitsel, O.; Raunser, S.: Structure of the Lifeact-F-actin complex. PLoS Biology 18 (11), e3000925, S. 1 - 18 (2020)

Pospich, S.; Merino, F.; Raunser, S.: Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure 28 (4), S. 437 - 449 (2020)

Merino, F.; Pospich, S.; Raunser, S.: Towards a structural understanding of the remodeling of the actin cytoskeleton. Seminars in Cell & Developmental Biology 102 (SI), S. 51 - 64 (2019)

Funk, J.; Merino, F.; Venkova, L.; Heydenreich, L.; Kierfeld, J.; Vargas, P.; Raunser, S.; Piel, M.; Bieling, P.: Profilin and formin constitute a pacemaker system for robust actin filament growth. eLife (e50963), e50963, S. 1 - 74 (2019)

Gatsogiannis, C.; Balogh, D.; Merino, F.; Sieber, S. A.; Raunser, S.: Cryo-EM structure of the ClpXP protein degradation machinery. Nature Structural and Molecular Biology 26 (10), S. 946 - 954 (2019)

Wagner, T.; Merino, F.; Stabrin, M.; Moriya, T.; Antoni, C.; Apelbaum, A.; Hagel, P.; Sitsel, O.; Raisch, T.; Prumbaum, D. et al.; Quentin, D.; Roderer, D.; Tacke, S.; Siebolds, B.; Schubert, E.; Shaikh, T. R.; Lill, P.; Gatsogiannis, C.; Raunser, S.: SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM. Communications Biology 2, 218, S. 1 - 13 (2019)

Herrera-Morande, A.; Castro-Fernández, V.; Merino, F.; Ramírez-Sarmiento, C. A.; Fernández , F. J.; Vega, M. C.; Guixé, V.: Protein topology determines substrate-binding mechanism in homologous enzymes. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (12), S. 2869 - 2878 (2018)

Gatsogiannis, C.; Merino, F.; Roderer, D.; Balchin, D.; Schubert, E.; Kuhlee, A.; Hayer-Hartl, M.; Raunser, S.: Tc toxin activation requires unfolding and refolding of a β-propeller. Nature, S. 1 - 25 (2018)

Merino, F.; Pospich, S.; Funk, J.; Wagner, T.; Küllmer, F.; Arndt, H.-D.; Bieling, P.; Raunser, S.: Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nature Structural Molecular Biology 25 (6), S. 528 - 537 (2018)

Vinayagam, D.; Mager, T.; Apelbaum, A.; Bothe, A.; Merino, F.; Hofnagel, O.; Gatsogiannis, C.; Raunser, S.: Electron cryo-microscopy structure of the canonical TRPC4 ion channel. eLife 7:e36615, S. 1 - 46 (2018)

Merino, F.; Raunser, S.: The complex simplicity of the bacterial cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America 115 (13), S. 3205 - 3206 (2018)

Castro-Fernandez, V.; Herrera-Morande, A.; Zamora, R.; Merino, F.; Gonzalez-Ordenes, F.; Padilla-Salinas, F.; Pereira, H. M.; Brandão-Neto , J.; Garratt, R. C.; Guixe, V.: Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. Journal of Biological Chemistry 292 (38), S. 15598 - 15610 (2017)

Moriya, T.; Saur, M.; Stabrin, M.; Merino, F.; Voicu, H.; Huang, Z.; Penczek, P. A.; Raunser, S.; Gatsogiannis, C.: High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE. Journal of Visualized Experiments (123), e55448, S. e55448:1 - e55448:11 (2017)

Merino, F.; Raunser, S.: The mother of all actins? eLife 5, S. e23354:1 - e23354:3 (2016)

Merino, F.; Raunser, S.: Cryo-EM as a tool for structure-based drug development. Angewandte Chemie International Edition, S. 1 - 29 (2016)