Publikationen von Kirill Alexandrov

Zeitschriftenartikel (77)

Zeitschriftenartikel
Tnimov, Z.; Guo, Z.; Gambin, Y.; Nguyen, U. T.T.; Wu, Y.-W.; Abankwa, D.; Stigter, A.; Collins, B. M.; Waldmann, H.; Goody, R. S. et al.; Alexandrov, K.: Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI. Journal of Biological Chemistry 287 (32), 1, S. 26549 - 26562 (2012)
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Deraeve, C.; Guo, Z.; Bon, R. S.; Blankenfeldt, W.; DiLucrezia, R.; Wolf, A.; Menninger, S.; Stigter, E. A.; Wetzel, S.; Choidas, A. et al.; Alexandrov, K.; Waldmann, H.; Goody, R. S.; Wu, Y.-W.: Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase. Journal of the American Chemical Society 134 (17), 1, S. 7384 - 7391 (2012)
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Das, D.; Tnimov, Z.; Nguyen, U. T. T.; Thimmaiah, G.; Lo, H.; Abankwa, D.; Wu, Y.; Goody, R. S.; Waldmann, H.; Alexandrov, K.: Flexible and General Synthesis of Functionalized Phosphoisoprenoids for the Study of Prenylation in vivo and in vitro. ChemBioChem 13 (5), 1, S. 674 - 683 (2012)
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Wu, Y.-W.; Goody, R. S.; Alexandrov, K.: Intein-Mediated Construction of a Library of Fluorescent Rab GTPase Probes. ChemBioChem 12 (18), 1, S. 2813 - 2821 (2011)
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Bon, R. S.; Guo, Z.; Stigter, E. A.; Wetzel, S.; Menninger, S.; Wolf, A.; Choidas, A.; Alexandrov, K.; Blankenfeldt, W.; Goody, R. S. et al.; Waldmann, H.: Structure-Guided Development of Selective RabGGTase Inhibitors. Angewandte Chemie International Edition 50 (21), 1, S. 4957 - 4961 (2011)
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Bon, R. S.; Guo, Z.; Stigter, E. A.; Wetzel, S.; Menninger, S.; Wolf, A.; Choidas, A.; Alexandrov, K.; Blankenfeldt, W.; Goody, R. S. et al.; Waldmann, H.: Structure-Guided Development of Selective RabGGTase Inhibitors. Angewandte Chemie 123 (21), 1, S. 5059 - 5063 (2011)
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Kushnir, S.; Cirstea, I. C.; Basiliya, L.; Lupilova, N.; Breitling, R.; Alexandrov, K.: Artificial linear episome-based protein expression system for protozoon Leishmania tarentolae. Molecular & Biochemical Parasitology 176 (2), 1, S. 69 - 79 (2011)
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Gazdag, E. M.; Cirstea, I. C.; Breitling, R.; Lukes, J.; Blankenfeldt, W.; Alexandrov, K.: Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae. Acta Crystallographica Section F - Structural Biology and Crystallization Communications F66 (8), 1, S. 871 - 877 (2010)
Zeitschriftenartikel
Wu, Y.-W.; Oesterlin, L. K.; Tan, K.-T.; Waldmann, H.; Alexandrov, K.; Goody, R. S.: Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. Nature Chemical Biology 6 (7), 1, S. 534 - 540 (2010)
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Nguyen, U. T. T.; Goody, R. S.; Alexandrov, K.: Understanding and Exploiting Protein Prenyltransferases. ChemBioChem 11 (9), 1, S. 1194 - 1201 (2010)
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Weinrich, D.; Lin, P.-C.; Jonkheijm, P.; Nguyen, U. T. T.; Schröder, H.; Niemeyer, C. M.; Alexandrov, K.; Goody, R.; Waldmann, H.: Oriented Immobilization of Farnesylated Proteins by the Thiol-Ene Reaction. Angewandte Chemie International Edition 49 (7), 1, S. 1252 - 1257 (2010)
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Weinrich, D.; Lin, P.-C.; Jonkheijm, P.; Nguyen, U. T. T.; Schröder, H.; Niemeyer, C. M.; Alexandrov, K.; Goody, R.; Waldmann, H.: Oriented Immobilization of Farnesylated Proteins by the Thiol-Ene Reaction. Angewandte Chemie 122 (7), 1, S. 1274 - 1279 (2010)
Zeitschriftenartikel
Mureev, S.; Kovtun, O.; Nguyen, U. T. T.; Alexandrov, K.: Species-independent translational leaders facilitate cell-free expression. Nature Biotechnology 27 (8), 1, S. 747 - 752 (2009)
Zeitschriftenartikel
Rucktäschel, R.; Thoms, S.; Sidorovitch, V.; Halbach, A.; Pechlivanis, M.; Volkmer, R.; Alexandrov, K.; Kuhlmann, J.; Rottensteiner, H.; Erdmann, R.: Farnesylation of Pex19p is required for its structural integrity and function in peroxisome biogenesis. Journal of Biological Chemistry 284 (31), 1, S. 20885 - 20896 (2009)
Zeitschriftenartikel
Bleimling, N.; Alexandrov, K.; Goody, R.; Itzen, A.: Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli. Protein Expression and Purification 65 (2), 1, S. 190 - 196 (2009)
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Foldynová-Trantírková, S.; Matulová, J.; Dötsch, V.; Löhr, F.; Cirstea, I.; Alexandrov, K.; Breitling, R.; Lukeš, J.; Trantírek, L.: A Cost-effective Amino-acid-type Selective Isotope Labeling of Proteins Expressed in Leishmania tarentolae. Journal of Biomolecular Structure & Dynamics 26 (6), 1, S. 755 - 762 (2009)
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Wu, Y.-W.; Goody, R. S.; Abagyan, R.; Alexandrov, K.: Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation. Journal of Biological Chemistry 284 (19), 1, S. 13185 - 13192 (2009)
Zeitschriftenartikel
Nguyen, U. T. T.; Guo, Z.; Delon, C.; Wu, Y.; Deraeve, C.; Fränzel, B.; Bon, R. S.; Blankenfeldt, W.; Goody, R. S.; Waldmann, H. et al.; Wolters, D.; Alexandrov, K.: Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chemical Biology 5 (4), 1, S. 227 - 237 (2009)
Zeitschriftenartikel
Bergbrede, T.; Chuky, N.; Schoebel, S.; Blankenfeldt, W.; Geyer, M.; Fuchs, E.; Goody, R. S.; Barr, F.; Alexandrov, K.: Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains. Journal of Biological Chemistry 284 (5), 1, S. 2628 - 2635 (2009)
Zeitschriftenartikel
Tan, K.-T.; Guiu-Rozas, E.; Bon, R. S.; Guo, Z.; Delon, C.; Wetzel, S.; Arndt, S.; Alexandrov, K.; Waldmann, H.; Goody, R. S. et al.; Wu, Y.-W.; Blankenfeldt, W.: Design, Synthesis, and Characterization of Peptide-Based Rab Geranylgeranyl Transferase Inhibitors. Journal of Medicinal Chemistry 52 (24), 1, S. 8025 - 8037 (2009)
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