Publikationen von Christian Ottmann

Möcklinghoff, S.; Van Otterlo, W. A. L.; Rose, R.; Fuchs, S.; Zimmermann, T. J.; Dominguez Seoane, M.; Waldmann, H.; Ottmann, C.; Brunsveld, L.: Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold- Detection Approach. Journal of Medicinal Chemistry 54 (7), 1, S. 2005 - 2011 (2011)

Molzan, M.; Schumacher, B.; Ottmann, C.; Baljuls, A.; Polzien, L.; Weyand, M.; Thiel, P.; Rose, R.; Rose, M.; Kuhenne, P. et al.; Kaiser, M.; Rapp, U. R.; Kuhlmann, J.; Ottmann, C.: Impaired Binding of 14-3-3 to C-Raf in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling. Molecular and Cellular Biology 30 (19), 1, S. 4698 - 4711 (2010)

Schumacher, B.; Skwarczynska, M.; Rose, R.; Ottmann, C.: Structure of a 14-3-3σ-YAP phosphopeptide complex at 1.15 A resolution. Acta Crystallographica Section F-Structural Biology and Crystallization Communications F66 (9), 1, S. 978 - 984 (2010)

Schumacher, B.; Mondry, J.; Thiel, P.; Weyand, M.; Ottmann, C.: Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer. FEBS Letters 584 (8), 1, S. 1443 - 1448 (2010)

Kaiser, M.; Ottmann, C.: The First Small-Molecule Inhibitor of 14-3-3s: Modulating the Master Regulator. ChemBioChem 11 (15), 1, S. 2085 - 2087 (2010)

Möcklinghoff, S.; Rose, R.; Carraz, M.; Visser, A.; Ottmann, C.; Brunsveld, L.: Synthesis and Crystal Structure of a Phosphorylated Estrogen Receptor Ligand Binding Domain. ChemBioChem 11 (16), 1, S. 2251 - 2254 (2010)

Ottmann, C.; Hauske, P.; Kaiser, M.: Activation Instead of Inhibition: Targeting Proenzymes for Small-Molecule Intervention. ChemBioChem 11 (5), 1, S. 637 - 639 (2010)

Rose, R.; Erdmann, S.; Bovens, S.; Wolf, A.; Rose, M.; Hennig, S.; Waldmann, H.; Ottmann, C.: Identification and Structure of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions. Angewandte Chemie International Edition 49 (24), 1, S. 4129 - 4132 (2010)

Rose, R.; Erdmann, S.; Bovens, S.; Wolf, A.; Rose, M.; Hennig, S.; Waldmann, H.; Ottmann, C.: Identifizierung und Struktur von niedermolekularen Substanzen als Stabilisatoren von 14-3-3-Protein-Protein-Wechselwirkungen. Angewandte Chemie 122 (24), 1, S. 4223 - 4226 (2010)

Ottmann, C.; Rose, R.; Huttenlocher, F.; Cedzich, A.; Hauske, P.; Kaiser, M.; Huber, R.; Schaller, A.: Structural basis for Ca²⁺-independence and activation by homodimerization of tomato subtilase 3. Proceedings of the National Academy of Sciences of the United States of America 106 (40), 1, S. 17223 - 17228 (2009)

Küfner, I.; Ottmann, C.; Oecking, C.; Nürnberger, T.: Cytolytic toxins as triggers of plant immune response. Plant Signaling & Behavior 4 (10), 1, S. 977 - 979 (2009)

Rose, R.; Huttenlocher, F.; Cedzich, A.; Kaiser, M.; Schaller, A.; Ottmann, C.: Purification, crystallization and preliminary X-ray diffration analysis of a plant subtilase. Acta Crystallographica Section F. Structural Biology and Crystallization Communications F65 (5), 1, S. 522 - 525 (2009)

Ottmann, C.; Weyand, M.; Sassa, T.; Inoue, T.; Kato, N.; Wittinghofer, A.; Oecking, C.: A Structural Rationale for Selective Stabilization of Anti-tumor Interactions of 14-3-3 proteins by Cotylenin A. Journal of Molecular Biology 386 (4), 1, S. 913 - 919 (2009)

Hauske, P.; Mamant, N.; Hasenbein, S.; Nickel, S.; Ottmann, C.; Clausen, T.; Ehrmann, M.; Kaiser, M.: Peptidic small molecule activators of the stress sensor DegS. Molecular BioSystems 5, 1, S. 980 - 985 (2009)

Hauske, P.; Meltzer, M.; Ottmann, C.; Krojer, T.; Clausen, T.; Ehrmann, M.; Kaiser, M.: Selectivity profiling of DegP substrates and inhibitors. Bioorganic & Medicinal Chemistry 17, 1, S. 2920 - 2924 (2009)

Ottmann, C.; Weyand, M.; Wolf, A.; Kuhlmann, J.; Ottmann, C.: Applicability of superfolder YFP bimolecular fluorescence complementation in vitro. Biological Chemistry 390 (1), 1, S. 81 - 90 (2009)

Simard, J. R.; Grütter, C.; Pawar, V.; Aust, B.; Wolf, A.; Rabiller, M.; Wulfert, S.; Robubi, A.; Klüter, S.; Ottmann, C. et al.; Rauh, D.: High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38α. Journal of American Chemical Society 131 (51), 1, S. 18478 - 18488 (2009)

Luberacki, B.; Weyand, M.; Seitz, U.; Koch, W.; Oecking, C.; Ottmann, C.: Purification, crystallization and preliminary X-ray diffraction analysis of an oomycete-derived Nep1-like protein. Acta Crystallographica Section F, Structural Biology and Crystallization Communications F64 (12), 1, S. 1178 - 1180 (2008)

Hauske, P.; Ottmann, C.; Meltzer, M.; Ehrmann, M.; Kaiser, M.: Allosteric Regulation of Proteases. ChemBioChem 9 (18), 1, S. 2920 - 2928 (2008)

Ottmann, C.; Marco, S.; Jaspert, N.; Marcon, C.; Schauer, N.; Weyand, M.; Vandermeeren, C.; Duby, G.; Boutry, M.; Wittinghofer, A. et al.; Rigaud, J.-L.; Oecking, C.: Structure of a 14-3-3 Coordinated Hexamer of the Plant Plasma Membrane H⁺-ATPase by Combining X-Ray Crystallography and Electron Cryomicroscopy. Molecular Cell 25 (3), 1, S. 427 - 440 (2007)