Publications of Christian Ottmann

Journal Article (41)

Journal Article
Joo, Y.; Schumacher, B.; Landrieu, I.; Bartel, M.; Smet-Nocca, C.; Jang, A.; Choi, H. S.; Jeon, N. L.; Chang, K.-A.; Kim, H.-S. et al.; Ottmann, C.; Suh, Y.-H.: Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau. The FASEB Journal 29 (10), pp. 4133 - 4144 (2015)
Journal Article
Menzel, M.; Meckbach, D.; Weide, B.; Toussaint, N. C.; Schilbach, K.; Noor, S.; Eigentler, T.; Ikenberg, K.; Busch, C.; Quintanilla-Martinez, L. et al.; Kohlhofer, U.; Göke, A.; Göke, F.; Handgretinger, R.; Ottmann, C.; Bastian, B. C.; Garbe, C.; Röcken, M.; Perner, S.; Kohlbacher, O.; Bauer, J.: In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient surviva. Pigment Cell & Melanoma Research 27 (4), pp. 671 - 673 (2014)
Journal Article
Novakova, J.; Izsakova, A.; Grivalsky, T.; Ottmann, C.; Farkasovsky, M.: Improved method for high-efficiency electrotransformation of Escherichia coli with the large BAC plasmids. Folia Microbiologica 59 (1), pp. 53 - 61 (2014)
Journal Article
Molzan, M.; Kasper, S.; Röglin, L.; Skwarczynska, M.; Sassa, T.; Inoue, T.; Breitenbuecher, F.; Ohkanda, J.; Kato, N.; Schuler, M. et al.; Ottmann, C.: Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. ACS Chemical Biology 8 (9), 1, pp. 1869 - 1875 (2013)
Journal Article
Ottmann, C.; Robinson, J.: Inhibition and stabilization of protein-protein interactions. Preface. Bioorganic & Medicinal Chemistry 21 (14), 1, p. 3981 - 3981 (2013)
Journal Article
De Vries-van Leeuwen, I. J.; Pereira, D. d. C.; Flach, K. D.; Piersma, S. R.; Haase, C.; Bier, D.; Yalcin, Z.; Michalides, R.; Feenstra, K. A.; Jiménez, C. R. et al.; de Greef, T. F. A.; Brunsveld, L.; Ottmann, C.; Zwart, W.; de Boer, A. H.: Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface. Proceedings of the National Academy of Sciences of the United States of America 110 (22), 1, pp. 8894 - 8899 (2013)
Journal Article
Anders, C.; Higuchi, Y.; Koschinsky, K.; Bartel, M.; Schumacher, B.; Thiel, P.; Nitta, H.; Preisig-Müller, R.; Schlichthörl, G.; Renigunta, V. et al.; Ohkanda, J.; Daut, J.; Kato, N.; Ottmann, C.: A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface. Chemistry & Biology 20 (4), 1, pp. 583 - 593 (2013)
Journal Article
Fuchs, S.; Nguyen, H. D.; Phan, T. T. P.; Burton, M. F.; Nieto, L.; De Vries-van Leeuwen, I. J.; Schmidt, A.; Goodarzifard, M.; Agten, S. M.; Rose, R. et al.; Ottmann, C.; Milroy, L.-G.; Brunsveld, L.: Proline Primed Helix Length as a Modulator of the Nuclear Receptor-Coactivator Interaction. Journal of the American Chemical Society 135 (11), 1, pp. 4364 - 4371 (2013)
Journal Article
Bier, D.; Rose, R.; Bravo-Rodriguez, K.; Bartel, M.; Ramirez-Anguita, J. M.; Dutt, S.; Wilch, C.; Klärner, F.-G.; Sánchez-García, E.; Schrader, T. et al.; Ottmann, C.: Molecular tweezers modulate 14-3-3 protein-protein interactions. Nature Chemistry 5 (3), 1, pp. 234 - 239 (2013)
Journal Article
Molzan, M.; Ottmann, C.: Subcellular localization of full-length human myeloid leukemia factor 1 (MLF1) is independent of 14-3-3 proteins. Cellular & Molecular Biology Letters 18 (1), 1, pp. 137 - 148 (2013)
Journal Article
Skwarczynska, M.; Molzan, M.; Ottmann, C.: Activation of NF-κB signalling by fusicoccin-induced dimerization. Proceedings of the National Academy of Sciences of the United States of America 110 (5), 1, pp. E377 - E386 (2013)
Journal Article
Arens, J.; Engels, B.; Klopries, S.; Jennewein, S.; Ottmann, C.; Schulz, F.: Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family. Chemical Communications 49 (39), 1, pp. 4337 - 4339 (2013)
Journal Article
Milroy, L.-G.; Brunsveld, L.; Ottmann, C.: Stabilization and Inhibition of Protein–Protein Interactions: The 14-3-3 Case Study. ACS Chemical Biology 8 (1), 1, pp. 27 - 35 (2013)
Journal Article
Ottmann, C.: Small-molecule modulators of 14-3-3 protein–protein interactions. Bioorganic & Medicinal Chemistry, Article in press, online ahead of print, pp. 1 - 5 (2012)
Journal Article
Molzan, M.; Ottmann, C.: Synergistic Binding of the Phosphorylated S233- and S259-Binding Sites of C-RAF to One 14-3-3ζ Dimer. Journal of Molecular Biology 423 (4), 1, pp. 486 - 495 (2012)
Journal Article
Bier, C.; Knauer, S. K.; Wünsch, D.; Kunst, L.; Scheiding, S.; Kaiser, M.; Ottmann, C.; Krämer, O. H.; Stauber, R. H.: Allosteric inhibition of Taspase1’s pathobiological activity by enforced dimerization in vivo. FASEB Journal 26 (8), 1, pp. 3421 - 3429 (2012)
Journal Article
Richter, A.; Rose, R.; Hedberg, C.; Waldmann, H.; Ottmann, C.: An Optimised Small-Molecule Stabiliser of the 14-3-3–PMA2 Protein–Protein Interaction. Chemistry - A European Journal 18 (21), 1, pp. 6520 - 6527 (2012)
Journal Article
Röglin, L.; Thiel, P.; Kohlbacher, O.; Ottmann, C.: Covalent attachment of pyridoxalphosphate derivatives to 14-3-3 proteins. Proceedings of the National Academy of Sciences of the United States of America 109 (18), 1, pp. E1051 - E1053 (2012)
Journal Article
Kaiser, M.; Ottmann, C.: In Silico Identification of an Interferon Inhibitor. ChemMedChem 7 (4), 1, pp. 555 - 557 (2012)
Journal Article
Molzan, M.; Weyand, M.; Rose, R.; Ottmann, C.: Structural insights of the MLF1/14-3-3 interaction. FEBS Journal 279 (4), 1, pp. 563 - 571 (2012)
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