Publikationen von Yao-Wen Wu

Yi, L.; Sun, H.; Itzen, A.; Triola, G.; Waldmann, H.; Goody, R. S.; Wu, Y.-W.: One-Pot Dual-Labeling of a Protein by Two Chemoselective Reactions. Angewandte Chemie International Edition 50 (36), 1, S. 8287 - 8290 (2011)

Yi, L.; Sun, H.; Wu, Y.-W.; Triola, G.; Waldmann, H.; Goody, R. S.: A Highly Efficient Strategy for Modification of Proteins at the C Terminus. Angewandte Chemie International Edition 49 (49), 1, S. 9417 - 9421 (2010)

Yi, L.; Sun, H.; Wu, Y.-W.; Triola, G.; Waldmann, H.; Goody, R. S.: A Highly Efficient Strategy for Modification of Proteins at the C Terminus. Angewandte Chemie 122 (49), 1, S. 9607 - 9611 (2010)

Wu, Y.-W.; Goody, R. S.: Probing protein function by chemical modification. Journal of Peptide Science 16 (10), 1, S. 514 - 523 (2010)

Wu, Y.-W.; Oesterlin, L. K.; Tan, K.-T.; Waldmann, H.; Alexandrov, K.; Goody, R. S.: Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes. Nature Chemical Biology 6 (7), 1, S. 534 - 540 (2010)

Wu, Y.-W.; Goody, R. S.; Abagyan, R.; Alexandrov, K.: Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation. Journal of Biological Chemistry 284 (19), 1, S. 13185 - 13192 (2009)

Nguyen, U. T. T.; Guo, Z.; Delon, C.; Wu, Y.; Deraeve, C.; Fränzel, B.; Bon, R. S.; Blankenfeldt, W.; Goody, R. S.; Waldmann, H. et al.; Wolters, D.; Alexandrov, K.: Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chemical Biology 5 (4), 1, S. 227 - 237 (2009)

Tan, K.-T.; Guiu-Rozas, E.; Bon, R. S.; Guo, Z.; Delon, C.; Wetzel, S.; Arndt, S.; Alexandrov, K.; Waldmann, H.; Goody, R. S. et al.; Wu, Y.-W.; Blankenfeldt, W.: Design, Synthesis, and Characterization of Peptide-Based Rab Geranylgeranyl Transferase Inhibitors. Journal of Medicinal Chemistry 52 (24), 1, S. 8025 - 8037 (2009)

Guo, Z.; Wu, Y.-W.; Das, D.; Delon, C.; Cramer, J.; Yu, S.; Thuns, S.; Lupilova, N.; Waldmann, H.; Brunsveld, L. et al.; Goody, R. S.; Alexandrov, K.; Blankenfeldt, W.: Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. The EMBO Journal 27 (18), 1, S. 2444 - 2456 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie International Edition 47 (20), 1, S. 3747 - 3750 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu-Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie 120 (20), 1, S. 3807 - 3810 (2008)

Wu, Y.-W.; Alexandrov, K.; Brunsveld, L.: Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase. Nature Protocols 2 (11), 1, S. 2704 - 2711 (2007)

Wu, Y.-W.; Tan, K.-T.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators. Proceedings of the National Academy of Sciences of the United States of America 104 (30), 1, S. 12294 - 12299 (2007)

Zhang, L.; Wu, Y.; Brunsveld, L.: A Synthetic Supramolecular Construct Modulating Protein Assembley in Cells. Angewandte Chemie International Edition 46 (11), 1, S. 1798 - 1802 (2007)

Zhang, L.; Wu, Y.; Brunsveld, L.: A Synthetic Supramolecular Construct Modulating Protein Assembley in Cells. Angewandte Chemie 119 (11), 1, S. 1830 - 1834 (2007)

Wu, Y.-W.; Waldmann, H.; Reents, R.; Ebetino, F. H.; Goody, R. S.; Alexandrov, K.: A Protein Fluorescence Amplifier: Continuous Fluorometric Assay for Rab Geranylgeranyltransferase. ChemBioChem 7 (12), 1, S. 1859 - 1861 (2006)

Dursina, B.; Reents, R.; Delon, C.; Wu, Y.; Kulharia, M.; Thutewohl, M.; Veligodsky, A.; Kalinin, A.; Evstifeev, V.; Ciobanu, D. et al.; Szedlacsek, S. E.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Identification and Specificity Profiling of Protein Prenyltransferase Inhibitors Using New Fluorescent Phosphoisoprenoids. Journal of the American Chemical Society 128 (9), 1, S. 2822 - 2835 (2006)

Alexandrov, K.; Goody, R.; Waldmann, H.; Wu, Y.: The Study of Rab GTPase Recycling Using Semi-synthetic Prenylated Proteins. In: Chemical Biology - Learning through Case Studies, 14, S. 189 - 205 (Hg. Herbert Waldmann, P. J.). Wiley-VCH, Weinheim (2009)

Yi, L.: Development of site-specific labeling strategies for protein modification and synthesis of Rab probes. Dissertation, Technische Universität Dortmund, Dortmund (2013)

Wu, Y.: Identification of RabGGTase inhibitors and mechanistic studies of Rab GTPase prenylation and recyling using fluorescent sensors. Dissertation, Technische Universität, Dortmund (2008)