Publikationen von Petra Janning

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi , H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, S. 1 - 37 (2019)

Laraia, L.; Friese, A.; Corkery, D. P.; Konstantinidis, G.; Erwin, N.; Hofer, W.; Karatas, H.; Klewer, L.; Brockmeyer, A.; Metz, M. et al.; Schölermann, B.; Dwivedi, M.; Li, L.; Rios-Munoz, P.; Köhn, M.; Winter, R.; Vetter, I. R.; Ziegler, S.; Janning, P.; Wu, Y.-W.; Waldmann, H.: The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature Chemical Biology 15 (7), S. 710 - 720 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie International Edition, S. 1 - 14 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie, S. 1 - 14 (2019)

Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, S. 1 - 12 (2019)

Uhlenbrock, N.; Smith, S.; Weisner, J.; Landel, I.; Lindemann, M.; Le, T. A.; Hardick, J.; Gontla, R.; Scheinpflug, R.; Czodrowski, P. et al.; Janning, P.; Depta, L.; Quambusch, L.; Müller, M. P.; Engels, B.; Rauh, D.: Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chemical Science 10 (12), S. 3573 - 3585 (2019)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEd targeting PROTAC that impairs lipid metabolism. Angewandte Chemie 132 (14), S. 5644 - 5650 (2019)

Schulte-Zweckel, J.; Schneidewind, T.; Abad, J. L.; Brockmeyer, A.; Janning, P.; Triola, G.: Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins. Chemical Communications 54 (97), S. 13742 - 13745 (2018)

Kaiser, N.; Mejuch, T.; Fedoryshchak, R.; Janning, P.; Tate, E. W.; Waldmann, H.: Photoactivatable Myristic Acid Probes for UNC119-Cargo Interactions. Chembiochem 20 (2), S. 134 - 139 (2018)

Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), S. 1095 - 1106 (2018)

Ulbrich, S.; Janning, P.; Seidel, R.; Matschke, J.; Gonsberg, A.; Jung, S.; Glatzel, M.; Engelhard, M.; Winklhofer, K. F.; Tatzelt, J.: Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease. PLoS One 13 (5), e0197659, S. 1 - 15 (2018)

Koos, B.; Christmann, J.; Plettenberg, S.; Käding, D.; Becker, J.; Keteku, M.; Klein, C.; Imtiaz, S.; Janning, P.; Bastiaens, P. I. H. et al.; Wehner, F.: Hypertonicity-induced cation channels (HICCs) in HepG2 cells: architecture and role in proliferation vs. apoptosis. The Journal of Physiology - London, S. 1 - 35 (2018)

Küchler, P.; Zimmermann, G.; Winzker, M.; Janning, P.; Waldmann, H.; Ziegler, S.: Identification of novel PDEd interacting proteins. Bioorganic & Medicinal Chemistry 26 (8), S. 1426 - 1434 (2017)

Martín-Gago, P.; Fansa, E. K.; Winzker, M.; Murarka, S.; Janning, P.; Schultz-Fademrecht, C.; Baumann, M.; Wittinghofer, A.; Waldmann, H.: Covalent Protein Labeling at Glutamic Acids. Cell chemical biology 24 (5), S. 589 - 597 (2017)

Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie International Edition 56 (9), S. 2423 - 2428 (2017)

Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6d-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie 129 (9), S. 2463 - 2468 (2017)

Stiller, C.; Krüger, D. M.; Brauckhoff, N.; Schmidt, M.; Janning, P.; Salamon, H.; Grossmann, T.: Translocation of an Intracellular Protein via Peptide-Directed Ligation. ACS Chemical Biology, S. 1 - 6 (2016)

Qian, Y.; Schürmann, M.; Janning, P.; Hedberg, C.; Waldmann, H.: Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity. Angewandte Chemie 128 (27), S. 7897 - 7902 (2016)

Qian, Y.; Schürmann, M.; Janning, P.; Hedberg, C.; Waldmann, H.: Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity. Angewandte Chemie International Edition 55 (27), S. 7766 - 7771 (2016)

Schürmann, M.; Janning, P.; Ziegler, S.; Waldmann, H.: Small-Molecule Target Engagement in Cells. Cell Chemical Biology 23 (4), S. 435 - 441 (2016)