Publications of Sonja Sievers

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell‐Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie International Edition 60 (18), pp. 9869 - 9874 (2021)

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell-Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie 133 (18), pp. 9957 - 9962 (2021)

Grigalunas, M.; Burhop, A.; Zinken, S.; Pahl, A.; Gally, J.-M.; Wild, N.; Mantel, Y.; Sievers, S.; Foley, D. J.; Scheel, R. et al.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Natural product fragment combination to performance-diverse pseudo-natural products. Nature Communications 12 (1), 1883, pp. 1 - 11 (2021)

Ziegler, S.; Sievers, S.; Waldmann, H.: Morphological profiling of small molecules. Cell Chemical Biology 28 (3), pp. 300 - 319 (2021)

Liu, J.; Cremosnik, G. S.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie International Edition 60 (9), pp. 4648 - 4656 (2020)

Schneidewind, T.; Brause, A.; Pahl, A.; Burhop, A.; Mejuch, T.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological profiling enables the identification of common mode of action for small molecules with different targets. Chembiochem 21 (22), pp. 3197 - 3207 (2020)

Liu, J.; Cremosnik, G. S.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie 133 (9), pp. 4698 - 4706 (2020)

Karatas, H.; Akbarzadeh, M.; Adihou, H.; Hahne, G.; Pobbati, A. V.; Yihui Ng, E.; Guéret, S. M.; Sievers, S.; Pahl, A.; Metz, M. et al.; Zinken, S.; Dötsch, L.; Nowak, C.; Thavam, S.; Friese, A.; Kang, C.; Hong, W.; Waldmann, H.: Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket. Journal of Medicinal Chemistry 63 (20), pp. 11972 - 11989 (2020)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), pp. 5721 - 5729 (2019)

Pobbati, A. V.; Mejuch, T.; Chakraborty, S.; Karatas, H.; Bharath, S. R.; Guéret, S. M.; Goy, P.-A.; Hahne, G.; Pahl, A.; Sievers, S. et al.; Guccione, E.; Song, H.; Waldmann, H.; Hong, W.: Identification of Quinolinols as Activators of TEAD-dependent Transcription. ACS Chemical Biology, pp. 1 - 35 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), pp. 5770 - 5778 (2019)

Zimmermann, S.; Akbarzadeh, M.; Otte, F.; Strohmann, C.; Sankar, M. G.; Ziegler, S.; Pahl, A.; Sievers, S.; Kumar, K.: A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides. Chemistry – A European Journal 25, pp. 1 - 7 (2019)

Christoforow, A.; Wilke, J.; Binici, A.; Pahl, A.; Ostermann, C.; Sievers, S.; Waldmann, H.: Design, Synthesis and Phenotypic Profiling of Pyrano-Furo-Pyridone Pseudo Natural Products. Angewandte Chemie International Edition 58 (41), pp. 14715 - 14723 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, pp. 1 - 28 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3. Angewandte Chemie, pp. 1 - 28 (2019)

Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, pp. 1 - 12 (2019)

Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie International Edition 58 (4), pp. 1062 - 1066 (2019)

Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie 131 (4), pp. 1074 - 1078 (2019)

Christoforow, A.; Wilke, J.; Binici, A.; Pahl, A.; Ostermann, C.; Sievers, S.; Waldmann, H.: Design, Synthesis and Phenotypic Profiling of Pyrano-Furo-Pyridone Pseudo Natural Products. Angewandte Chemie 131 (41), pp. 14857 - 14865 (2019)

Karageorgis, G.; Reckzeh, E. S.; Ceballos, J.; Schwalfenberg, M.; Sievers, S.; Ostermann, C.; Pahl, A.; Ziegler, S.; Waldmann, H.: Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3. Nature Chemistry 10, pp. 1103 - 1111 (2018)