Publications of Kirill Alexandrov

Dursina, B.; Reents, R.; Delon, C.; Wu, Y.; Kulharia, M.; Thutewohl, M.; Veligodsky, A.; Kalinin, A.; Evstifeev, V.; Ciobanu, D. et al.; Szedlacsek, S. E.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Identification and Specificity Profiling of Protein Prenyltransferase Inhibitors Using New Fluorescent Phosphoisoprenoids. Journal of the American Chemical Society 128 (9), 1, pp. 2822 - 2835 (2006)

Watzke, A.; Köhn, M.; Gutierrez-Rodriguez, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody, R. S. et al.; Waldmann, H.: Site-Selective Protein Immobilization by Staudinger Ligation. Angewandte Chemie International Edition 45 (9), 1, pp. 1408 - 1412 (2006)

Watzke, A.; Köhn, M.; Gutierrez-Rodriguez, M.; Wacker, R.; Schröder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody, R. S. et al.; Waldmann, H.: Site-Selective Protein Immobilization by Staudinger Ligation. Angewandte Chemie 118 (9), 1, pp. 1436 - 1440 (2006)

Pylypenko, O.; Rak, A.; Durek, T.; Kushnir, S.; Dursina, B. E.; Thomae, N. H.; Constantinescu, A. T.; Brunsveld, L.; Watzke, A.; Waldmann, H. et al.; Goody, R. S.; Alexandrov, K.: Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling. EMBO Journal 25, 1, pp. 13 - 23 (2006)

De Araújo, A. D.; Palomo, J. M.; Cramer, J.; Köhn, M.; Schröder, H.; Wacker, R.; Niemeyer, C.; Alexandrov, K.; Waldmann, H.: Diels-Alder Ligation and Surface Immobilization of Proteins. Angewandte Chemie International Edition 45 (2), 1, pp. 296 - 301 (2006)

de Araújo, A. D.; Palomo, J. M.; Cramer, J.; Köhn, M.; Schröder, H.; Wacker, R.; Niemeyer, C.; Alexandrov, K.; Waldmann, H.: Diels-Alder Ligation and Surface Immobilization of Proteins. Angewandte Chemie 118 (2), 1, pp. 302 - 307 (2006)

Goody, R. S.; Rak, A.; Alexandrov, K.: The structural and mechanistic basis for recycling of Rab proteins between membrane compartments. Cellular and Molecular Life Sciences 62 (15), 1, pp. 1657 - 1670 (2005)

Kushnir, S.; Gase, K.; Breitling, R.; Alexandrov, K.: Development of an inducible protein expression system based on the protozoan host Leishmania tarentolae. Protein Expression & Purification 42 (1), 1, pp. 37 - 46 (2005)

Brunsveld, L.; Watzke, A.; Durek, T.; Alexandrov, K.; Goody, R. S.; Waldmann, H.: Synthesis of Functionalized Rab GTPases by a Combination of Solution- or Solid-Phase Lipopeptide Synthesis with Expressed Protein Ligation. Chemistry - A European Journal 11 (9), 1, pp. 2756 - 2772 (2005)

Watzke, A.; Brunsveld, L.; Durek, T.; Alexandrov, K.; Rak, A.; Goody, R. S.; Waldmann, H.: Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases. Organic & Biomolecular Chemistry 3 (7), 1, pp. 1157 - 1164 (2005)

Bergbrede, T.; Pylypenko, O.; Rak, A.; Alexandrov, K.: Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8Å resolution. Journal of Structural Biology 152, 1, pp. 235 - 238 (2005)

Dursina, B.-E.; Reents, R.; Niculae, A.; Veligodsky, A.; Breitling, R.; Pyatkov, K.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: A genetically encodable microtag for chemo-enzymatic derivatization and purification of recombinant proteins. Protein Expression and Purification 39 (1), 1, pp. 71 - 81 (2005)

Goody, R. S.; Durek, T.; Waldmann, H.; Brunsveld, L.; Alexandrov, K.: Application of Protein Semisynthesis for the Construction of Functionalized Posttranslationally modified Rab GTPases. GTPases Regulating Membrane Targeting and Fusion, 4, pp. 29 - 42 (2005)

Durek, T.; Alexandrov, K.; Goody, R. S.; Hildebrand, A.; Heinemann, I.; Waldmann, H.: Synthesis of Fluorescently Labeled Mono- and Diprenylated Rab7 GTPase. 50, 1, pp. 16368 - 16378 (2004)

Rak, A.; Pylypenko, O.; Niculae, A.; Pyatkov, K.; Goody, R. S.; Alexandrov, K.: Structure of the Rab7: REP-1 complex: Insights into the mechanism of rab prenylation and choroideremia disease. Cell 117 (6), 1, pp. 749 - 760 (2004)

Durek, T.; Goody, R. S.; Alexandrov, K.: In Vitro Semisynthesis and Applications of C-terminally Modified Rab Proteins. Bioconjugation Protocols - Strategies and Methods, 17, pp. 233 - 244 (2004)

Goody, R. S.; Alexandrov, K.; Engelhard, M.: Herstellung modifizierter Proteine durch kombinierte Synthese und Biosynthese. BIOspektrum 9 (1), 1, pp. 42 - 45 (2003)

Pylypenko, O.; Rak, A.; Reents, R.; Niculae, A.; Sidorovitch, V.; Cioaca, M.-D.; Bessolitsyna, E.; Thomä, N. H.; Waldmann, H.; Schlichting, I. et al.; Goody, R. S.; Alexandrov, K.: Structure of rab escort protein-1 in complex with Rab geranylgeranyltransferase. Molecular Cell 11 (2), 1, pp. 483 - 494 (2003)

Rak, A.; Pylypenko, O.; Durek, T.; Watzke, A.; Kushnir, S.; Brunsveld, L.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase. Science 302 (5645), 1, pp. 646 - 650 (2003)

Rak, A.; Pylypenko, O.; Niculae, A.; Goody, R. S.; Alexandrov, K.: Crystallization and preliminary X-ray diffraction analysis of monoprenylated Rab7 GTPase in complex with Rab escort protein 1. Journal of Structural Biology 141 (1), 1, pp. 93 - 95 (2003)