Publications of Roger S. Goody

Nguyen, U. T. T.; Guo, Z.; Delon, C.; Wu, Y.; Deraeve, C.; Fränzel, B.; Bon, R. S.; Blankenfeldt, W.; Goody, R. S.; Waldmann, H. et al.; Wolters, D.; Alexandrov, K.: Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chemical Biology 5 (4), 1, pp. 227 - 237 (2009)

Bergbrede, T.; Chuky, N.; Schoebel, S.; Blankenfeldt, W.; Geyer, M.; Fuchs, E.; Goody, R. S.; Barr, F.; Alexandrov, K.: Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains. Journal of Biological Chemistry 284 (5), 1, pp. 2628 - 2635 (2009)

Tan, K.-T.; Guiu-Rozas, E.; Bon, R. S.; Guo, Z.; Delon, C.; Wetzel, S.; Arndt, S.; Alexandrov, K.; Waldmann, H.; Goody, R. S. et al.; Wu, Y.-W.; Blankenfeldt, W.: Design, Synthesis, and Characterization of Peptide-Based Rab Geranylgeranyl Transferase Inhibitors. Journal of Medicinal Chemistry 52 (24), 1, pp. 8025 - 8037 (2009)

Itzen, A.; Goody, R. S.: Key Determinants of Rab Specificity. Structure 16 (10), 1, pp. 1437 - 1439 (2008)

Kulharia, M.; Goody, R. S.; Jackson, R. M.: Information Theory-Based Scoring Function for the Structure-Based Prediction of Protein-Ligand Binding Affinity. Journal of Chemical Information and Modeling 48 (10), 1, pp. 1990 - 1998 (2008)

Guo, Z.; Wu, Y.-W.; Das, D.; Delon, C.; Cramer, J.; Yu, S.; Thuns, S.; Lupilova, N.; Waldmann, H.; Brunsveld, L. et al.; Goody, R. S.; Alexandrov, K.; Blankenfeldt, W.: Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. The EMBO Journal 27 (18), 1, pp. 2444 - 2456 (2008)

Mannherz, H. G.; Ballweber, E.; Hegyi, G.; Goody, R. S.: Cross-Linked Long-Pitch Actin Dimer Forms Stoichiometric Complexes with Gelsolin Segment 1 and/or Deoxyribonuclease I that Nonproductively Interact with Myosin Subfragment 1. Biochemistry 47, 1, pp. 9335 - 9343 (2008)

Ignatev, A.; Kravchenko, S.; Rak, A.; Goody, R. S.; Pylypenko, O.: A Structural Model of the GDP Dissociation Inhibitor Rab Membrane Extraction Mechanism. Journal of Biological Chemistry 283 (26), 1, pp. 18377 - 18384 (2008)

Pylypenko, O.; Schönichen, A.; Ludwig, D.; Ungermann, C.; Goody, R. S.; Rak, A.; Geyer, M.: Farnesylation of the SNARE Protein Ykt6 Increases Its Stability and Helical Folding. Journal of Molecular Biology 377 (5), 1, pp. 1334 - 1345 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie International Edition 47 (20), 1, pp. 3747 - 3750 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu-Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie 120 (20), 1, pp. 3807 - 3810 (2008)

Milic, J.; Seidel, R.; Becker, C. F. W.; Goody, R. S.; Engelhard, M.: Semisynthesis of H-Ras with a glutamic acid methylester at position 61. Peptide Science 90 (3), 1, pp. 399 - 405 (2008)

Wu, Y.-W.; Tan, K.-T.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators. Proceedings of the National Academy of Sciences of the United States of America 104 (30), 1, pp. 12294 - 12299 (2007)

Nguyen, U. T. T.; Cramer, J.; Gomis, J.; Reents, R.; Gutierrez-Rodriguez, M.; Goody, R. S.; Alexandrov, K.; Waldmann, H.: Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization. ChemBioChem 8 (4), 1, pp. 408 - 423 (2007)

Itzen, A.; Rak, A.; Goody, R. S.: Sec2 is a Highly Efficient Exchange Factor for the Rab Protein Sec4. Journal of Molecular Biology 365, 1, pp. 1359 - 1367 (2007)

Becker, C. F. W.; Marsac, Y.; Hazarika, P.; Moser, J.; Goody, R. S.; Niemeyer, C. M.: Functional Immobilization of the Small GTPase Rab6A on DNA-Gold Nanoparticles by Using a Site-Specifically Attached Poly(ethylene glycol) Linker and Thiol Place-Exchange Reaction. ChemBioChem 8 (1), 1, pp. 32 - 36 (2007)

Budde, B. S.; Binner, P.; Waldmüller, S.; Höhne, W.; Blankenfeldt, W.; Hassfeld, S.; Brömsen, J.; Dermintzoglou, A.; Wieczorek, M.; May, E. et al.; Kirst, E.; Selignow, C.; Rackebrandt, K.; Müller, M.; Goody, R. S.; Vosberg, H.-P.; Nürnberg, P.; Scheffold, T.: Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the β-Myosin Heavy Chain Gene. PLoS One 2 (12), e1362, pp. 1 - 9 (2007)

Wu, Y.-W.; Waldmann, H.; Reents, R.; Ebetino, F. H.; Goody, R. S.; Alexandrov, K.: A Protein Fluorescence Amplifier: Continuous Fluorometric Assay for Rab Geranylgeranyltransferase. ChemBioChem 7 (12), 1, pp. 1859 - 1861 (2006)

Brunsveld, L.; Kuhlmann, J.; Alexandrov, K.; Wittinghofer, A.; Goody, R. S.; Waldmann, H.: Lipidated Ras and Rab Peptides and Proteins - Synthesis, Structure, and Function. Angewandte Chemie International Edition 45 (40), 1, pp. 6622 - 6646 (2006)

Brunsveld, L.; Kuhlmann, J.; Alexandrov, K.; Wittinghofer, A.; Goody, R. S.; Waldmann, H.: Lipidierte Ras- und Rab-Peptide und -Proteine: Synthese, Struktur und Funktion. Angewandte Chemie 118 (40), 1, pp. 6774 - 6798 (2006)