Publikationen von Andrea Musacchio

Polley, S.; Müschenborn, H.; Terbeck, M.; De Antoni, A.; Vetter, I. R.; Dogterom, M.; Musacchio, A.; Volkov, V. A.; Huis in´t Veld, P. J.: Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding. EMBO Journal (2023)

Chen, C.; Piano, V.; Alex, A.; Hahn, S. J.; Huis in´t Veld, P. J.; Roy, B.; Fergle, D.; Musacchio, A.; Joglekar, A. P.: The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex. Nature Communications 14 (1) (2023)

d'Amico, E.; Ud Din Ahmad, M.; Cmentowski, V.; Girbig, M.; Müller, F.; Wohlgemuth, S.; Brockmeyer, A.; Maffini, S.; Vetter, I. R.; Carter, A. P. et al.; Perrakis, A.; Musacchio, A.: Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin. The Journal of Cell Biology: JCB 221 (2022)

Schwietert, F.; Volkov, V. A.; Huis in´t Veld, P. J.; Dogterom, M.; Musacchio, A.; Kierfeld, J.: Strain stiffening of Ndc80 complexes attached to microtubule plus ends. Biophysical Journal (2022)

Celestino, R.; Gama, J. B.; Castro-Rodrigues, A. F.; Barbosa, D. B.; Rocha, H.; d'Amico, E.; Musacchio, A.; Carvalho, A. X.; Morais-Cabral, J. H.; Gassmann, R.: JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport. The Journal of Cell Biology: JCB (2022)

Pesenti, M.; Raisch, T.; Conti, D.; Walstein, K.; Hoffmann, I.; Vogt, D.; Prumbaum, D.; Vetter, I. R.; Raunser, S.; Musacchio, A.: Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization. Molecular Cell 82, S. 1 - 19 (2022)

Raisch, T.; Ciossani, G.; d'Amico, E.; Cmentowski, V.; Carmignani, S.; Maffini, S.; Merino, F.; Wohlgemuth, S.; Vetter, I. R.; Raunser, S. et al.; Musacchio, A.: Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. The EMBO Journal, e110411, S. 1 - 22 (2022)

Musacchio, A.: On the role of phase separation in the biogenesis of membraneless compartments. The EMBO Journal, e109952, S. 1 - 20 (2022)

Martin, I. M.; Aponte-Santamaría , C.; Schmidt, L.; Hedtfeld, M.; Iusupov, A.; Musacchio, A.; Gräter, F.: Phosphorylation tunes elongation propensity and cohesiveness of INCENP's intrinsically disordered region. Journal of Molecular Biology (London) 434 (1), 167387, S. 1 - 37 (2021)

van den Boom, J.; Kueck, A. F.; Kravic, B.; Müschenborn, H.; Giesing, M.; Pan, D.; Kaschani, F.; Kaiser, M.; Musacchio, A.; Meyer, H.: Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly. Nature Structural and Molecular Biology 28 (12), S. 964 - 971 (2021)

Huis in´t Veld, P. J.; Wohlgemuth, S.; Koerner, C.; Müller, F.; Janning, P.; Musacchio, A.: Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes. Protein Science 31 (2), S. 528 - 537 (2021)

Walstein, K.; Petrovic, A.; Pan, D.; Hagemeier, B.; Vogt, D.; Vetter, I. R.; Musacchio, A.: Assembly principles and stoichiometry of a complete human kinetochore module. Science Advances 7 (27), eabg1037, S. 1 - 22 (2021)

Müller, F.; Friese, A.; Pathe, C.; Cardoso da Silva, R.; Bravo Rodriguez, K.; Musacchio, A.; Bange, T.: Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization. Science Advances 7 (3), eabc8590, S. 1 - 13 (2021)

Piano, V.; Alex, A.; Stege, P.; Maffini, S.; Stoppiello, G. A.; Huis in´t Veld, P. J.; Vetter, I. R.; Musacchio, A.: CDC20 assists its catalytic incorporation in the mitotic checkpoint complex. Science 371 (6524), S. 67 - 71 (2021)

Singh, P.; Pesenti, M.; Maffini, S.; Carmignani, S.; Hedtfeld, M.; Petrovic, A.; Srinivasamani, A.; Bange, T.; Musacchio, A.: BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis. Molecular Cell 81 (1), S. 67 - 87 (2020)

Kong, M.; Cutts, E. E.; Pan, D.; Beuron, F.; Kaliyappan, T.; Xue, C.; Morris, E. P.; Musacchio, A.; Vannini, A.; Greene, E. C.: Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA. Molecular Cell 79 (1), S. 99 - 114 (2020)

Allan, L. A.; Camacho Reis, M.; Ciossani, G.; Huis in´t Veld, P. J.; Wohlgemuth, S.; Kops, G. J.; Musacchio, A.; Saurin, A. T.: Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint. The EMBO Journal 39 (12), e103180, S. 1 - 16 (2020)

Huis in´t Veld, P. J.; Volkov, V. A.; Stender, I. D.; Musacchio, A.; Dogterom, M.: Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling. eLife 8:e49539, e49539, S. 1 - 29 (2019)

Pan, D.; Walstein, K.; Take, A.; Bier, D.; Kaiser, N.; Musacchio, A.: Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing. Nature Communications 10 (1), 4046, S. 1 - 18 (2019)

Alex, A.; Piano, V.; Polley, S.; Stuiver, M.; Voss, S.; Ciossani, G.; Overlack, K.; Voss, B.; Wohlgemuth, S.; Petrovic, A. et al.; Wu, Y.-W.; Selenko, P.; Musacchio, A.; Maffini, S.: Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology. eLife 8, e48287, S. 1 - 50 (2019)