Publikationen von Axel Pahl

Schneidewind, T.; Brause, A.; Pahl, A.; Burhop, A.; Mejuch, T.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological profiling enables the identification of common mode of action for small molecules with different targets. Chembiochem 21 (22), S. 3197 - 3207 (2020)

Liu, J.; Cremosnik, G. S.; Otte, F.; Pahl, A.; Sievers, S.; Strohmann, C.; Waldmann, H.: Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products. Angewandte Chemie 133 (9), S. 4698 - 4706 (2020)

Karatas, H.; Akbarzadeh, M.; Adihou, H.; Hahne, G.; Pobbati, A. V.; Yihui Ng, E.; Guéret, S. M.; Sievers, S.; Pahl, A.; Metz, M. et al.; Zinken, S.; Dötsch, L.; Nowak, C.; Thavam, S.; Friese, A.; Kang, C.; Hong, W.; Waldmann, H.: Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket. Journal of Medicinal Chemistry 63 (20), S. 11972 - 11989 (2020)

Foley, D. J.; Zinken, S.; Corkery, D.; Laraia, L.; Pahl, A.; Wu, Y.-W.; Waldmann, H.: Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor. Angewandte Chemie, International Edition 59 (11), S. 1 - 17 (2020)

Foley, D. J.; Zinken, S.; Corkery, D.; Laraia, L.; Pahl, A.; Wu, Y.-W.; Waldmann, H.: Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor. Angewandte Chemie 132 (11), S. 1 - 17 (2020)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), S. 5721 - 5729 (2019)

Pobbati, A. V.; Mejuch, T.; Chakraborty, S.; Karatas, H.; Bharath, S. R.; Guéret, S. M.; Goy, P.-A.; Hahne, G.; Pahl, A.; Sievers, S. et al.; Guccione, E.; Song, H.; Waldmann, H.; Hong, W.: Identification of Quinolinols as Activators of TEAD-dependent Transcription. ACS Chemical Biology, S. 1 - 35 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), S. 5770 - 5778 (2019)

Zimmermann, S.; Akbarzadeh, M.; Otte, F.; Strohmann, C.; Sankar, M. G.; Ziegler, S.; Pahl, A.; Sievers, S.; Kumar, K.: A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides. Chemistry – A European Journal 25, S. 1 - 7 (2019)

Christoforow, A.; Wilke, J.; Binici, A.; Pahl, A.; Ostermann, C.; Sievers, S.; Waldmann, H.: Design, Synthesis and Phenotypic Profiling of Pyrano-Furo-Pyridone Pseudo Natural Products. Angewandte Chemie International Edition 58 (41), S. 14715 - 14723 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, S. 1 - 28 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3. Angewandte Chemie, S. 1 - 28 (2019)

Christoforow, A.; Wilke, J.; Binici, A.; Pahl, A.; Ostermann, C.; Sievers, S.; Waldmann, H.: Design, Synthesis and Phenotypic Profiling of Pyrano-Furo-Pyridone Pseudo Natural Products. Angewandte Chemie 131 (41), S. 14857 - 14865 (2019)

Karageorgis, G.; Reckzeh, E. S.; Ceballos, J.; Schwalfenberg, M.; Sievers, S.; Ostermann, C.; Pahl, A.; Ziegler, S.; Waldmann, H.: Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3. Nature Chemistry 10, S. 1103 - 1111 (2018)

Pahl, A.; Waldmann, H.; Kumar, K.: Exploring Natural Product Fragments for Drug and Probe Discovery. Chimia 71 (10), S. 653 - 660 (2017)

Firth, J. D.; Craven, P. G. E.; Lilburn, M.; Pahl, A.; Marsden, S. P.; Nelson, A.: A biosynthesis-inspired approach to over twenty diverse natural product-like scaffolds. Chemical Communications 52 (63), S. 9837 - 9840 (2016)

Pahl, A.; Sievers, S.: The Cell Painting Assay as a Screening Tool for the Discovery of Bioactivities in New Chemical Matter. In: Systems Chemical Biology; Methods in Molecular Biology, Vol. 1888, S. 115 - 126. Springer Verlag Humana Press, New York, NY (2019)

Gally, J.-M.; Pahl, A.; Waldmann, H.: Identifying bioactivity of pseudo-natural products using the Cell Painting assay, Arkivoc, S. 89 - 104 (2021)