Publikationen von Slava Ziegler

Zeitschriftenartikel (81)

Zeitschriftenartikel
Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie, S. 1 - 14 (2019)
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Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, S. 1 - 12 (2019)
Zeitschriftenartikel
Schneidewind, T.; Kapoor, S.; Garivet, G.; Karageorgis, G.; Narayan, R.; Vendrell Navarro, G.; Antonchick, A. P.; Ziegler, S.; Waldmann, H.: The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype. Cell Chemical Biology 26 (4), S. 512 - 523 (2019)
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Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie International Edition 58 (4), S. 1062 - 1066 (2019)
Zeitschriftenartikel
Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie 131 (4), S. 1074 - 1078 (2019)
Zeitschriftenartikel
Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEd targeting PROTAC that impairs lipid metabolism. Angewandte Chemie 132 (14), S. 5644 - 5650 (2019)
Zeitschriftenartikel
Li, H.; Gontla, R.; Flegel, J.; Merten , C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie International Edition 58 (1), S. 307 - 311 (2018)
Zeitschriftenartikel
Xin, X.; Zimmermann, S.; Flegel, J.; Otte, F.; Knauer, L.; Strohmann, C.; Ziegler, S.; Kumar, K.: Unravelling Synthesis and Chemistry of Stable, Acyclic and Double-Deficient 1,3-Butadienes: An endo-selective Diels-Alder Route to Hedgehog Pathway Inhibitors. Chemistry – A European Journal 25 (11), S. 2717 - 2722 (2018)
Zeitschriftenartikel
Karageorgis, G.; Reckzeh, E. S.; Ceballos, J.; Schwalfenberg, M.; Sievers, S.; Ostermann, C.; Pahl, A.; Ziegler, S.; Waldmann, H.: Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3. Nature Chemistry 10, S. 1103 - 1111 (2018)
Zeitschriftenartikel
Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie International Edition 57 (43), S. 14250 - 14254 (2018)
Zeitschriftenartikel
Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie 130 (43), S. 14446 - 14450 (2018)
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Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), S. 1095 - 1106 (2018)
Zeitschriftenartikel
Sankar, M. G.; Roy, S.; Tran, T. T. N.; Wittstein, K.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Kumar, K.: Scaffold Diversity Synthesis Delivers Complex, Structurally, and Functionally Distinct Tetracyclic Benzopyrones. ChemistryOpen 7 (4), S. 302 - 309 (2018)
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Pries, V.; Nöcker, C.; Khan, D.; Johnen, P.; Hong, Z.; Tripathi, A.; Keller, A.-L.; Fitz, M.; Perruccio, F.; Filipuzzi, I. et al.; Thavam, S.; Aust, T.; Riedl, R.; Ziegler, S.; Bono, F.; Schaaf, G.; Bankaitis, V. A.; Waldmann, H.; Hoepfner, D.: Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties. Cell Chemical Biology 25 (3), S. 279 - 290 (2018)
Zeitschriftenartikel
Höing, S.; Yeh, T.-Y.; Baumann, M.; Martinez, N. E.; Habenberger , P.; Kremer, L.; Drexler, H. C. A.; Küchler, P.; Reinhardt, P.; Choidas, A. et al.; Zischinsky, M.-L.; Zischinsky, G.; Nandini, S.; Ledray, A. P.; Ketcham, S. A.; Reinhardt, L.; Abo-Rady, M.; Glatza, M.; King, S. J.; Nussbaumer, P.; Ziegler, S.; Klebl, B.; Schroer, T. A.; Schöler, H. R.; Waldmann, H.; Sterneckert, J.: Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein. Cell Chemical Biology 25, S. 1 - 13 (2018)
Zeitschriftenartikel
Li, H.; Gontla, R.; Flegel, J.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie 131 (1), S. 313 - 317 (2018)
Zeitschriftenartikel
Wilke, J.; Kawamura, T.; Watanabe, N.; Osada, H.; Ziegler, S.; Waldmann, H.: Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion. Bioorganic & Medicinal Chemistry 26 (8), S. 1453 - 1461 (2017)
Zeitschriftenartikel
Kremer, L.; Schultz-Fademrecht, C.; Baumann, M.; Habenberger, P.; Choidas, A.; Klebl, B.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Ziegler, S. et al.; Schneider, G.; Waldmann, H.: Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction. Angewandte Chemie International Edition 56 (42), S. 13021 - 13025 (2017)
Zeitschriftenartikel
Sheremet, M.; Kapoor, S.; Schröder, P.; Kumar, K.; Ziegler, S.; Waldmann, H.: Small Molecules Inspired by the Natural Product Withanolides as Potent Inhibitors of Wnt Signaling. ChemBioChem: A European Journal of Chemical Biology 18 (18), S. 1797 - 1806 (2017)
Zeitschriftenartikel
Kremer, L.; Schultz-Fademrecht, C.; Baumann, M.; Habenberger, P.; Choidas, A.; Klebl, B.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Ziegler, S. et al.; Schneider, G.; Waldmann, H.: Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction. Angewandte Chemie 129, S. 1 - 6 (2017)
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