Publikationen von Slava Ziegler

Reckzeh, E. S.; Karageorgis, G.; Schwalfenberg, M.; Ceballos, J.; Nowacki, J.; Stroet, M. C.M.; Binici, A.; Knauer, L.; Brand, S.; Choidas, A. et al.; Strohmann, C.; Ziegler, S.; Waldmann, H.: Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth. Cell Chemical Biology 26, S. 1 - 41 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, S. 1 - 28 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3. Angewandte Chemie, S. 1 - 28 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi, H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, International Edition, S. 1 - 37 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi , H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, S. 1 - 37 (2019)

Furuta, T.; Mizukami, Y.; Asano, L.; Kotake, K.; Ziegler, S.; Yoshida, H.; Watanabe, M.; Sato, S.-i.; Waldmann, H.; Nishikawa, M. et al.; Uesugi, M.: Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators. ACS Chemical Biology, S. 1 - 6 (2019)

Laraia, L.; Friese, A.; Corkery, D. P.; Konstantinidis, G.; Erwin, N.; Hofer, W.; Karatas, H.; Klewer, L.; Brockmeyer, A.; Metz, M. et al.; Schölermann, B.; Dwivedi, M.; Li, L.; Rios-Munoz, P.; Köhn, M.; Winter, R.; Vetter, I. R.; Ziegler, S.; Janning, P.; Wu, Y.-W.; Waldmann, H.: The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature Chemical Biology 15 (7), S. 710 - 720 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie International Edition, S. 1 - 14 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie, S. 1 - 14 (2019)

Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, S. 1 - 12 (2019)

Schneidewind, T.; Kapoor, S.; Garivet, G.; Karageorgis, G.; Narayan, R.; Vendrell Navarro, G.; Antonchick, A. P.; Ziegler, S.; Waldmann, H.: The Pseudo Natural Product Myokinasib Is a Myosin Light Chain Kinase 1 Inhibitor with Unprecedented Chemotype. Cell Chemical Biology 26 (4), S. 512 - 523 (2019)

Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie International Edition 58 (4), S. 1062 - 1066 (2019)

Nemec, V.; Hylsová, M.; Maier, L.; Flegel, J.; Sievers, S.; Ziegler, S.; Schröder, M.; Berger, B.-T.; Chaikuad, A.; Valcíková, B. et al.; Uldrijan, S.; Drápela, S.; Soucek, K.; Waldmann, H.; Knapp, S.; Paruch, K.: Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway. Angewandte Chemie 131 (4), S. 1074 - 1078 (2019)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEd targeting PROTAC that impairs lipid metabolism. Angewandte Chemie 132 (14), S. 5644 - 5650 (2019)

Li, H.; Gontla, R.; Flegel, J.; Merten , C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie International Edition 58 (1), S. 307 - 311 (2018)

Xin, X.; Zimmermann, S.; Flegel, J.; Otte, F.; Knauer, L.; Strohmann, C.; Ziegler, S.; Kumar, K.: Unravelling Synthesis and Chemistry of Stable, Acyclic and Double-Deficient 1,3-Butadienes: An endo-selective Diels-Alder Route to Hedgehog Pathway Inhibitors. Chemistry – A European Journal 25 (11), S. 2717 - 2722 (2018)

Karageorgis, G.; Reckzeh, E. S.; Ceballos, J.; Schwalfenberg, M.; Sievers, S.; Ostermann, C.; Pahl, A.; Ziegler, S.; Waldmann, H.: Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3. Nature Chemistry 10, S. 1103 - 1111 (2018)

Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie International Edition 57 (43), S. 14250 - 14254 (2018)

Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie 130 (43), S. 14446 - 14450 (2018)

Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), S. 1095 - 1106 (2018)