Publikationen von Petra Janning

Goebel, L.; Kirschner, T.; Koska, S.; Rai, A.; Janning, P.; Maffini, S.; Vatheuer, H.; Czodrowski, P.; Goody, R. S.; Müller, M. et al.; Rauh, D.: Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife (2023)

Flegel, J.; Shaaban, S.; Jia, Z.-J.; Schulte, B.; Lian, Y.; Krzyzanowski, A.; Metz, M.; Schneidewind, T.; Wesseler , F.; Flegel, A. et al.; Reich, A.; Brause, A.; Xue, G.; Zhang, M.; Dötsch, L.; Stender, I. D.; Hoffmann, J.-E.; Scheel, R.; Janning, P.; Rastinejad, F.; Schade, D.; Strohmann, C.; Antonchick, A. P.; Sievers, S.; Alves, P.; Ziegler, S.; Waldmann, H.: The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. European Journal of Medicinal Chemistry (2022)

Grethe, C.; Schmidt, M.; Kipka, G.-M.; O'Dea, R.; Gallant, K.; Janning, P.; Gersch, M.: Structural basis for specific inhibition of the deubiquitinase UCHL1. Nature Communications 13 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie International Edition, S. 1 - 27 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie, S. 1 - 27 (2022)

Carnero Corrales, M. A.; Zinken, S.; Konstantinidis, G.; Rafehi, M.; Abdelrahman, A.; Wu, Y.-W.; Janning, P.; Müller, C. E.; Laraia, L.; Waldmann, H.: Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin. Cell Chemical Biology 28 (12), S. 1750 - 1757 (2021)

Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), S. 1780 - 1794 (2021)

Rousova, D.; Nivsarkar, V.; Altmannova, V.; Raina, V. B.; Funk, S. K.; Liedtke, D.; Janning, P.; Müller, F.; Reichle, H.; Vader, G. et al.; Weir , J. R.: Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation. eLife 10, 10:e72330, S. 1 - 75 (2021)

Huis in´t Veld, P. J.; Wohlgemuth, S.; Koerner, C.; Müller, F.; Janning, P.; Musacchio, A.: Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes. Protein Science 31 (2), S. 528 - 537 (2021)

Wolffgramm, J.; Buchmuller, B.; Palei, S.; Muñoz-López, Á.; Kanne, J.; Janning, P.; Schweiger, M. R.; Summerer, D.: Light-Activation of DNA-Methyltransferases. Angewandte Chemie International Edition 60 (24), S. 13507 - 13512 (2021)

Nöcker, C.; Kaiser, N.; Foley, D. J.; Sievers, S.; Janning, P.; Waldmann, H.; Laraia, L.: Thermal proteome profiling efficiently identifies ribosome destabilizing oxazolidinones. Tetrahedron 87, 132118, S. 1 - 7 (2021)

Wolffgramm, J.; Buchmuller, B.; Palei, S.; Muñoz-López, Á.; Kanne, J.; Janning, P.; Schweiger, M. R.; Summerer, D.: Light-Activation of DNA-Methyltransferases. Angewandte Chemie 133 (24), S. 13619 - 13624 (2021)

Witte, A.; Munoz-López, Á.; Metz, M.; Schweiger, M. R.; Janning, P.; Summerer, D.: Encoded, click-reactive DNA-binding domains for programmable capture of specific chromatin segments. Chemical Science 11 (46), S. 12506 - 12511 (2020)

Kawamura, T.; Futamura, Y.; Shang, E.; Muroi , M.; Janning, P.; Ueno, M.; Wilke, J.; Takeda, S.; Kondoh , Y.; Ziegler, S. et al.; Watanabe , N.; Waldmann, H.; Osada , H.: Discovery of small-molecule modulator of heterotrimeric G i-protein by integrated phenotypic profiling and chemical proteomics. BioScience, Biotechnology & Biochemistry, S. 1 - 7 (2020)

Swart, A.L.; Steiner, B.; Gomez-Valero, L.; Schütz, S.; Hannemann, M.; Janning, P.; Irminger, M.; Rothmeier, E.; Buchrieser, C.; Itzen, A. et al.; Panse, V. G.; Hilbi, H.: Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets. mBio 11 (2), e00405-20, S. 1 - 19 (2020)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEδ targeting PROTAC that impairs lipid metabolism. Angewandte Chemie, International Edition 59 (14), S. 5595 - 5601 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), S. 5721 - 5729 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), S. 5770 - 5778 (2019)

Lam, M. T.; Coppola, S.; Krumbach, O. H.F.; Prencipe, G.; Insalaco, A.; Cifaldi, C.; Brigida, I.; Zara, E.; Scala, S.; Di Cesare, S. et al.; Martinelli, S.; Di Rocco, M.; Pascarella, A.; Niceta, M.; Pantaleoni, F.; Ciolfi, A.; Netter, P.; Carisey, A. F.; Diehl, M.; Akbarzadeh, M.; Conti, F.; Merli, P.; Pastore, A.; Levi Mortera, S.; Camerini, S.; Farina, L.; Buchholzer, M.; Pannone, L.; Cao, T. N.; Coban-Akdemir, Z. H.; Jhangiani, S. N.; Muzny, D. M.; Gibbs, R. A.; Basso-Ricci, L.; Chiriaco, M.; Dvorsky, R.; Putignani, L.; Carsetti, R.; Janning, P.; Stray-Pedersen, A.; Erichsen, H. C.; Horne, A.; Bryceson, Y. T.; Torralba-Raga, L.; Ramme, K.; Rosti, V.; Bracaglia, C.; Messia, V.; Palma, P.; Finocchi, A.; Locatelli, F.; Chinn, I. K.; Lupski, J. R.; Mace, E. M.; Cancrini, C.; Aiuti, A.; Ahmadian, M. R.; Orange, J. S.; De Benedetti, F.; Tartaglia, M.: A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. Journal of Experimental Medicine, S. 1 - 22 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, S. 1 - 28 (2019)