Publications of Petra Janning

Führer , S.; Gallant, K.; Kaschani, F.; Kaiser, M.; Janning, P.; Waldmann, H.; Gersch, M.: Small Molecule-Induced Alterations of Protein Polyubiquitination Revealed by Mass-Spectrometric Ubiquitome Analysis. Angewandte Chemie, International Edition in English (2025)

Rezaei Adariani, S.; Agne, D.; Koska, S.; Burhop, A.; Seitz, C.; Warmers, J.; Janning, P.; Metz, M.; Pahl, A.; Sievers, S. et al.; Waldmann, H.; Ziegler, S.: Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of Medicinal Chemistry (2024)

Patil, S.; Cremosnik, G. S.; Dötsch, L.; Flegel, J.; Schulte, B.; Maier, K. C.; Zumer, K.; Cramer, P.; Janning, P.; Sievers, S. et al.; Waldmann, H.: Tafbromin selectively targets the TAF1 bromodomain. Angewandte Chemie, International Edition in English (2024)

Dötsch, L.; Davies, C.; Hennes, E.; Schönfeld, J.; Kumar, A.; Da Cruz Lopes Guita, C.; Ehrler, J. H.; Hiesinger, K.; Thavam, S.; Janning, P. et al.; Sievers, S.; Knapp, S.; Proschak, E.; Ziegler, S.; Waldmann, H.: Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of Medicinal Chemistry (2024)

Sitsel, O.; Wang, Z.; Janning, P.; Kroczek, L.; Wagner, T.; Raunser, S.: Yersinia entomophaga Tc toxin is released by T10SS-dependent lysis of specialized cell subpopulations. Nature Microbiology (2024)

O'Dea, R.; Kazi, N.; Hoffmann-Benito, A.; Zhao, Z.; Rechnagel, S.; Wendrich, K.; Janning, P.; Gersch, M.: Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36. Nature Chemical Biology (2023)

Goebel, L.; Kirschner, T.; Koska, S.; Rai, A.; Janning, P.; Maffini, S.; Vatheuer, H.; Czodrowski, P.; Goody, R. S.; Müller, M. et al.; Rauh, D.: Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. eLife (2023)

Flegel, J.; Shaaban, S.; Jia, Z.-J.; Schulte, B.; Lian, Y.; Krzyzanowski, A.; Metz, M.; Schneidewind, T.; Wesseler , F.; Flegel, A. et al.; Reich, A.; Brause, A.; Xue, G.; Zhang, M.; Dötsch, L.; Stender, I. D.; Hoffmann, J.-E.; Scheel, R.; Janning, P.; Rastinejad, F.; Schade, D.; Strohmann, C.; Antonchick, A. P.; Sievers, S.; Alves, P.; Ziegler, S.; Waldmann, H.: The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. European Journal of Medicinal Chemistry (2022)

Grethe, C.; Schmidt, M.; Kipka, G.-M.; O'Dea, R.; Gallant, K.; Janning, P.; Gersch, M.: Structural basis for specific inhibition of the deubiquitinase UCHL1. Nature Communications 13 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie International Edition, pp. 1 - 27 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie, pp. 1 - 27 (2022)

Carnero Corrales, M. A.; Zinken, S.; Konstantinidis, G.; Rafehi, M.; Abdelrahman, A.; Wu, Y.-W.; Janning, P.; Müller, C. E.; Laraia, L.; Waldmann, H.: Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin. Cell Chemical Biology 28 (12), pp. 1750 - 1757 (2021)

Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), pp. 1780 - 1794 (2021)

Rousova, D.; Nivsarkar, V.; Altmannova, V.; Raina, V. B.; Funk, S. K.; Liedtke, D.; Janning, P.; Müller, F.; Reichle, H.; Vader, G. et al.; Weir , J. R.: Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation. eLife 10, 10:e72330, pp. 1 - 75 (2021)

Huis in´t Veld, P. J.; Wohlgemuth, S.; Koerner, C.; Müller, F.; Janning, P.; Musacchio, A.: Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes. Protein Science 31 (2), pp. 528 - 537 (2021)

Wolffgramm, J.; Buchmuller, B.; Palei, S.; Muñoz-López, Á.; Kanne, J.; Janning, P.; Schweiger, M. R.; Summerer, D.: Light-Activation of DNA-Methyltransferases. Angewandte Chemie International Edition 60 (24), pp. 13507 - 13512 (2021)

Nöcker, C.; Kaiser, N.; Foley, D. J.; Sievers, S.; Janning, P.; Waldmann, H.; Laraia, L.: Thermal proteome profiling efficiently identifies ribosome destabilizing oxazolidinones. Tetrahedron 87, 132118, pp. 1 - 7 (2021)

Wolffgramm, J.; Buchmuller, B.; Palei, S.; Muñoz-López, Á.; Kanne, J.; Janning, P.; Schweiger, M. R.; Summerer, D.: Light-Activation of DNA-Methyltransferases. Angewandte Chemie 133 (24), pp. 13619 - 13624 (2021)

Witte, A.; Munoz-López, Á.; Metz, M.; Schweiger, M. R.; Janning, P.; Summerer, D.: Encoded, click-reactive DNA-binding domains for programmable capture of specific chromatin segments. Chemical Science 11 (46), pp. 12506 - 12511 (2020)

Kawamura, T.; Futamura, Y.; Shang, E.; Muroi , M.; Janning, P.; Ueno, M.; Wilke, J.; Takeda, S.; Kondoh , Y.; Ziegler, S. et al.; Watanabe , N.; Waldmann, H.; Osada , H.: Discovery of small-molecule modulator of heterotrimeric G i-protein by integrated phenotypic profiling and chemical proteomics. BioScience, Biotechnology & Biochemistry, pp. 1 - 7 (2020)