Publications of Herbert Waldmann

Xu, H.; Golz, C.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition. Angewandte Chemie International Edition 55 (27), pp. 7761 - 7765 (2016)

Xu, H.; Golz, C.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition. Angewandte Chemie 128 (27), pp. 7892 - 7896 (2016)

Tschapalda, K.; Zhang, Y.-Q.; Liu, L.; Golovnina, K.; Schlemper, T.; Eichmann, T. O.; Lal-Nag, M.; Sreenivasan, U.; McLenithan, J.; Ziegler, S. et al.; Sztalryd, C.; Lass, A.; Auld, D.; Oliver, B.; Waldmann, H.; Li, Z.; Shen, M.; Boxer, M. B.; Beller, M.: A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics. EBioMedicine 8, pp. 49 - 59 (2016)

Qian, Y.; Schürmann, M.; Janning, P.; Hedberg, C.; Waldmann, H.: Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity. Angewandte Chemie International Edition 55 (27), pp. 7766 - 7771 (2016)

Illich, D. J.; Zhang, M.; Ursu, A.; Osorno, R.; Kim, K.-P.; Yoon, J.; Araúzo-Bravo, M. J.; Wu, G.; Esch, D.; Sabour, D. et al.; Colby, D.; Grassme, K. S.; Chen, J.; Greber, B.; Höing, S.; Herzog, W.; Ziegler, S.; Chambers, I.; Gao, S.; Waldmann, H.; Schöler, H. R.: Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Reports 15 (4), pp. 787 - 800 (2016)

Schürmann, M.; Janning, P.; Ziegler, S.; Waldmann, H.: Small-Molecule Target Engagement in Cells. Cell Chemical Biology 23 (4), pp. 435 - 441 (2016)

Ursu, A.; Illich, D. J.; Takemoto, Y.; Porfetye, A. T.; Zhang, M.; Brockmeyer, A.; Janning, P.; Watanabe, N.; Osada, H.; Vetter, I. R. et al.; Ziegler, S.; Schöler, H. R.; Waldmann, H.: Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chemical Biology 23 (4), pp. 494 - 507 (2016)

Papke, B.; Murarka, S.; Vogel, H. A.; Martín-Gago, P.; Kovacevic, M.; Truxius, D.; Fansa, E. K.; Ismail, S.; Zimmermann, G.; Heinelt, K. et al.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.; Bastiaens, P. I. H.: Identification of pyrazolopyridazinones as PDEδ inhibitors. Nature Communications 7, 11360, pp. 1 - 9 (2016)

Cromm, P. M.; Schaubach, S.; Spiegel, J.; Fürstner, A.; Grossmann, T.; Waldmann, H.: Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides. Nature Communications 7, 11300, pp. 1 - 7 (2016)

Erwin, N.; Sperlich, B.; Garivet, G.; Waldmann, H.; Weise, K.; Winter, R.: Lipoprotein insertion into membranes of various complexity: lipid sorting, interfacial adsorption and protein clustering. Physical Chemistry Chemical Physics 18 (13), pp. 8954 - 8962 (2016)

Kapoor, S.; Waldmann, H.; Ziegler, S.: Novel approaches to map small molecule–target interactions. Bioorganic & Medicinal Chemistry, pp. 1 - 14 (2016)

Murarka, S.; Martín-Gago, P.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Fansa, E. K.; Ismail, S.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.: Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site. Chemistry – A European Journal 23 (25), pp. 6083 - 6093 (2016)

Pahl, A.; Lakemeyer, M.; Vielberg, M.-T.; Hackl, M. W.; Vomacka, J.; Korotkov, V. S.; Stein, M. L.; Fetzer, C.; Lorenz-Baath, K.; Richter, K. et al.; Waldmann, H.; Groll, M.; Sieber, S. A.: Reversible Inhibitors Arrest ClpP in a Defined Conformational State that Can Be Revoked by ClpX Association. Angewandte Chemie, International Edition 54 (52), pp. 15892 - 15896 (2015)

Pahl, A.; Lakemeyer, M.; Vielberg, M.-T.; Hackl, M. W.; Vomacka, J.; Korotkov, V. S.; Stein, M. L.; Fetzer, C.; Lorenz-Baath, K.; Richter, K. et al.; Waldmann, H.; Groll, M.; Sieber, S. A.: Reversible Inhibitoren arretieren ClpP in einer definierten Konformation, die durch Bindung von ClpX aufgehoben wird. Angewandte Chemie 127 (52), pp. 16121 - 16126 (2015)

Sellstedt, M.; Schwalfenberg, M.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection. Organic & Biomolecular Chemistry 14 (1), pp. 50 - 54 (2015)

Mejuch, T.; Van Hattum, H.; Triola, G.; Jaiswal, M.; Waldmann, H.: Specificity of Lipoprotein Chaperones for the Characteristic Lipidated Structural Motifs of their Cognate Lipoproteins. ChemBioChem: A European Journal of Chemical Biology 16 (17), pp. 2460 - 2465 (2015)

Cromm, P. M.; Spiegel, J.; Grossmann, T.; Waldmann, H.: Direct Modulation of Small GTPase Activity and Function. Angewandte Chemie, International Edition 54 (46), pp. 13516 - 13537 (2015)

Cromm, P. M.; Spiegel, J.; Grossmann, T.; Waldmann, H.: Direkte Modulation von Aktivität und Funktion kleiner GTPasen. Angewandte Chemie 127 (46), pp. 13718 - 13741 (2015)

Schröder, P.; Förster, T.; Kleine, S.; Becker, C.; Richters, A.; Ziegler, S.; Rauh, D.; Kumar, K.; Waldmann, H.: Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. Angewandte Chemie International Edition 54 (42), pp. 12398 - 12403 (2015)

Schröder, P.; Förster, T.; Kleine, S.; Becker, C.; Richters, A.; Ziegler, S.; Rauh, D.; Kumar, K.; Waldmann, H.: Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. Angewandte Chemie 127 (42), pp. 12575 - 12580 (2015)