Publications of Herbert Waldmann

Spiegel, J.; Cromm, P. M.; Zimmermann, G.; Grossmann, T.; Waldmann, H.: Small-molecule modulation of Ras signaling. Nature Chemical Biology 10 (8), pp. 613 - 622 (2014)

Vogel, A.; Nikolaus, J.; Weise, K.; Triola, G.; Waldmann, H.; Winter, R.; Herrmann, A.; Huster, D.: Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity. Biological Chemistry 395 (7-8), pp. 779 - 789 (2014)

Köhnke, M.; Delon, C.; Hastie, M. L.; Nguyen, U. T. T.; Wu, Y.-W.; Waldmann, H.; Goody, R. S.; Gorman, J. J.; Alexandrov, K.: Rab GTPase Prenylation Hierarchy and Its Potential Role in Choroideremia Disease. PLoS One 8 (12), pp. e81758:1 - e81758:11 (2013)

Narayan, R.; Bauer, J. O.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling. Angewandte Chemie - International Edition 52 (49), pp. 12892 - 12896 (2013)

Narayan, R.; Bauer, J. O.; Strohmann, C.; Antonchick, A. P.; Waldmann, H.: Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling. Angewandte Chemie 125 (49), pp. 13130 - 13134 (2013)

Takayama, H.; Jia, Z.-J.; Kremer, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection. Angewandte Chemie - International Edition 52 (47), pp. 12404 - 12408 (2013)

Takayama, H.; Jia, Z.-J.; Kremer, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection. Angewandte Chemie 125 (47), Epub ahead of print; no final pagination, pp. 12630 - 12634 (2013)

Werkmüller, A.; Triola, G.; Waldmann, H.; Winter, R.: Rotational and Translational Dynamics of Ras Proteins upon Binding to Model Membrane Systems. ChemPhysChem 14 (16), pp. 3698 - 3705 (2013)

Dakas, P.-Y.; Parga, J. A.; Höing, S.; Schöler, H. R.; Sterneckert, J.; Kumar, K.; Waldmann, H.: Discovery of Neuritogenic Compound Classes Inspired by Natural Products. Angewandte Chemie 125 (36), pp. 9755 - 9760 (2013)

Potowski, M.; Antonchick, A. P.; Waldmann, H.: Catalytic asymmetric exo-selective [6+3] cycloaddition of iminoesters with fulvenes. Chemical Communications 49 (71), pp. 7800 - 7802 (2013)

Zimmermann, G.; Papke, B.; Ismail, S.; Vartak, N.; Chandra, A.; Hoffmann, M.; Hahn, S. A.; Triola, G.; Wittinghofer, A.; Bastiaens, P. I. H. et al.; Waldmann, H.: Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature 497 (7451), 1, pp. 638 - 642 (2013)

Kapoor, S.; Werkmüller, A.; Goody, R. S.; Waldmann, H.; Winter, R.: Pressure Modulation of Ras-Membrane Interactions and Intervesicle Transfer. Journal of the American Chemical Society 135 (16), 1, pp. 6149 - 6156 (2013)

Antonchick, A. P.; Lopez Tosco, S.; Parga, J.; Sievers, S.; Schürmann, M.; Preut, H.; Höing, S.; Schöler, H. R.; Sterneckert, J.; Rauh, D. et al.; Waldmann, H.: Highly Enantioselective Catalytic Synthesis of Neurite Growth-Promoting Secoyohimbanes. Chemistry & Biology 20 (4), 1, pp. 500 - 509 (2013)

Gersch, M.; Gut, F.; Korotkov, V. S.; Lehmann, J.; Böttcher, T.; Rusch, M.; Hedberg, C.; Waldmann, H.; Klebe, G.; Sieber, S. A.: The Mechanism of Caseinolytic Protease (ClpP) Inhibition. Angewandte Chemie International Edition 52 (10), 1, pp. 3009 - 3014 (2013)

Gersch, M.; Gut, F.; Korotkov, V. S.; Lehmann, J.; Böttcher, T.; Rusch, M.; Hedberg, C.; Waldmann, H.; Klebe, G.; Sieber, S. A.: Der Inhibitionsmechanismus der caseinolytischen Protease (ClpP). Angewandte Chemie 125 (10), 1, pp. 3083 - 3088 (2013)

Ziegler, S.; Pries, V.; Hedberg, C.; Waldmann, H.: Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack. Angewandte Chemie International Edition 52 (10), 1, pp. 2744 - 2792 (2013)

Ziegler, S.; Pries, V.; Hedberg, C.; Waldmann, H.: Identifizierung der Zielproteine bioaktiver Verbindungen: Die Suche nach der Nadel im Heuhaufen. Angewandte Chemie 125 (10), 1, pp. 2808 - 2859 (2013)

Eschenbrenner-Lux, V.; Dückert, H.; Khedkar, V.; Bruss, H.; Waldmann, H.; Kumar, K.: Cascade Syntheses Routes to the Centrocountins. Chemistry - A European Journal 19 (7), 1, pp. 2294 - 2304 (2013)

Zimmermann, T. J.; Roy, S.; Martinez, N. E.; Ziegler, S.; Hedberg, C.; Waldmann, H.: Biology-oriented synthesis of a tetrahydroisoquinoline-based compound collection targeting microtubule polymerization. ChemBioChem 14 (3), 1, pp. 295 - 300 (2013)

Voigt, T.; Gerding-Reimers, C.; Tran, T. T. N.; Bergmann, S.; Lachance, H.; Schölermann, B.; Brockmeyer, A.; Janning, P.; Ziegler, S.; Waldmann, H.: A Natural Product Inspired Tetrahydropyran Collection Yields Mitosis Modulators that Synergistically Target CSE1L and Tubulin. Angewandte Chemie International Edition 52 (1), 1, pp. 410 - 414 (2013)