Publications of Aymelt Itzen

Roland, J. T.; Bryant, D. M.; Datta, A.; Itzen, A.; Mostov, K. E.; Goldenring, J. R.: Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization. Proceedings of the National Academy of Sciences of the United States of America 108 (7), 1, pp. 2789 - 2794 (2011)

Itzen, A.; Goody, R. S.: GTPases involved in vesicular trafficking: Structures and mechanisms. Seminars in Cell & Developmental Biology 22 (1), 1, pp. 48 - 56 (2011)

Goody, R. S.; Müller, M. P.; Schoebel, S.; Oesterlin, L. K.; Blümer, J.; Peters, H.; Blankenfeldt, W.; Itzen, A.: The versatile Legionella effector protein DrrA. Communicative & Integrative Biology 4 (1), 1, pp. 72 - 74 (2011)

Hou, X.; Hagemann, N.; Schoebel, S.; Blankenfeldt, W.; Goody, R. S.; Erdmann, K. S.; Itzen, A.: A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1. The EMBO Journal 30 (8), 1, pp. 1659 - 1670 (2011)

Müller, M. P.; Peters, H.; Blümer, J.; Blankenfeldt, W.; Goody, R. S.; Itzen, A.: The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b. Science 329 (5994), 1, pp. 946 - 949 (2010)

Schoebel, S.; Blankenfeldt, W.; Goody, R. S.; Itzen, A.: High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. EMBO Reports 11 (8), 1, pp. 598 - 604 (2010)

Schoebel, S.; Oesterlin, L. K.; Blankenfeldt, W.; Goody, R. S.; Itzen, A.: RabGDI Displacement by DrrA from Legionella Is a Consequence of Its Guanine Nucleotide Exchange Activity. Molecular Cell 36 (6), 1, pp. 1060 - 1072 (2009)

Bleimling, N.; Alexandrov, K.; Goody, R.; Itzen, A.: Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli. Protein Expression and Purification 65 (2), 1, pp. 190 - 196 (2009)

Itzen, A.; Goody, R. S.: Key Determinants of Rab Specificity. Structure 16 (10), 1, pp. 1437 - 1439 (2008)

Itzen, A.; Rak, A.; Goody, R. S.: Sec2 is a Highly Efficient Exchange Factor for the Rab Protein Sec4. Journal of Molecular Biology 365, 1, pp. 1359 - 1367 (2007)

Itzen, A.; Pylypenko, O.; Goody, R. S.; Alexandrov, K.; Rak, A.: Nucleotide exchange via local protein unfolding - structure of Rab8 in complex with MSS4. The EMBO Journal 25 (7), 1, pp. 1445 - 1455 (2006)

Itzen, A.; Bleimling, N.; Ignatev, A.; Pylypenko, O.; Rak, A.: Purification, crystallization and preliminary X-ray crystallographic analysis of mammalian MSS4-Rab8 GTPase protein complex. Acta Crystallographica Section F - Structural Biology and Crystallization Communications 62 (2), 1, pp. 113 - 116 (2006)

Goody, R. S.; Itzen, A.: Modulation of Small GTPases by Legionella. In: Molecular Mechanisms in Legionella Pathogenesis, pp. 117 - 133 (Ed. Hilbi, H.). Springer, Berlin [u.a.] (2013)

Blümer, J.: Membranlokalisation von Rab-Proteinen durch RabGEFs. Dissertation, Technische Universität Dortmund, Dortmund (2013)

Müller, M.: Mechanismen der reversiblen enzymatischen Adenylylierung von Rab-Proteinen. Dissertation, Technische Universität Dortmund, Dortmund (2013)

Schöbel, S.: Molekulare Grundlagen der Rab-Manipulation der Proteine DrrA und LidA aus Legionella pneumophila. Dissertation, Technische Universität Dortmund, Dortmund (2012)

Itzen, A.: Strukturelle und biochemische Einblicke in Mechanismen des Nukleotidaustauschs von Rab-Proteinen. Dissertation, Universität Dortmund, Dortmund (2007)

Itzen, A.: Construction of semisynthetic fluorescent Rab GTPases, analysis of their interaction with cellular membranes in vivo and kinetic analysis of their prenylation in vitro. Diploma, Universität Hannover, Hannover (2003)

Friese, T.: Entwicklung eines Verfahrens zur selektiven Anreicherung und Identifizierung von Rab-GEFs. Master, Technische Universität Dortmund, Dortmund (2013)

Vieweg, S.: Charakterisierung kovalenter Addukte zwischen kleinen GTPasen und dem Nukleotidderivat AcrylGTP. Master, Technische Universität München, München (2012)